Rchr
J-GLOBAL ID:201801017317654624   Update date: Sep. 09, 2024

Takahashi Masato

タカハシ マサト | Takahashi Masato
Affiliation and department:
Research field  (2): Pharmaceuticals - chemistry and drug development ,  Clinical pharmacy
Research keywords  (5): 複素環 ,  天然物化学 ,  薬物代謝学 ,  プロドラッグ ,  有機合成化学
Research theme for competitive and other funds  (2):
  • 2019 - 2022 親化合物の化学構造に影響されない水溶性プロドラッグ修飾基の開発
  • 2017 - 2019 カルボキシルエステラーゼの基質特異性を考慮した臓器選択的プロドラッグの分子設計
Papers (22):
  • Masato Takahashi, Kohei Takahashi, Taichi Yamaguchi, Takeshi Kohama, Masakiyo Hosokawa. Functional roles and localization of hydrolases in the Japanese mitten crab Eriocheir japonica. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 2024. 270. 110932-110932
  • Daisuke Takani, Masato Takahashi, Masakiyo Hosokawa. Synthesis and evaluation of indomethacin prodrugs with a diester structure that are metabolically activated by human carboxylesterases. Xenobiotica. 2023. 1-11
  • Masato Takahashi, Ibuki Hirota, Tomoyuki Nakano, Tomoyuki Kotani, Daisuke Takani, Kana Shiratori, Yura Choi, Masami Haba, Masakiyo Hosokawa. Effects of steric hindrance and electron density of ester prodrugs on controlling the metabolic activation by human carboxylesterase. Drug Metabolism and Pharmacokinetics. 2021. 100391-100391
  • Masato Takahashi, Yeon Joo Lee, Teruhiko Kanayama, Yusuke Kondo, Kazuki Nishio, Kota Mukai, Masami Haba, Masakiyo Hosokawa. Design, synthesis and biological evaluation of water-soluble phenytoin prodrugs considering the substrate recognition ability of human carboxylesterase 1. European Journal of Pharmaceutical Sciences. 2020. 105455-105455
  • Masato Takahashi, Masakiyo Hosokawa. Recent Advancement in Prodrugs (Chapter 11). 2020
more...
Education (1):
  • 2011 - 2014 千葉大学大学院 医学薬学府 創薬生命科学専攻(博士課程)
Professional career (1):
  • 博士(薬学) (千葉大学)
Work history (2):
  • 2024/04 - 現在 Chiba Institute of Science Faculty of Pharmacy
  • 2014/04 - 現在 Chiba Institute of Science Faculty of Pharmacy
Committee career (2):
  • 2024/09 - 第19回ナノ・バイオメディカル学会大会 運営委員会委員長
  • 2024/09 - 第19回ナノ・バイオメディカル学会サテライトシンポジウム 運営委員会委員長
Association Membership(s) (2):
THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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