Research field (2):
Physiology
, Neuroscience - general
Research keywords (4):
Sleep
, Orexin
, Narcolepsy
, 加齢
Research theme for competitive and other funds (10):
2022 - 2026 ポジティブな感情を欠損させたマウスの睡眠・覚醒と行動変化
2022 - 2025 REM睡眠開始における扁桃体基底外側核のドーパミンシグナルの役割の解明
2022 - 2025 老化に伴う睡眠異常の解明と免疫変容の神経科学的理解
2022 - 2024 REM睡眠ゲーティングに関わる扁桃体内ドーパミンシグナルの役割の解明
2018 - 2023 報酬系による睡眠制御メカニズムの解明
2018 - 2021 The analysis of neural pathways in arousal maintenance and behavioral alteration under orexin
2015 - 2018 Analysis of sleep-wake regulatory system by optogenetics featuring cone opsins.
2016 - 2017 中枢概日時計のニューロンタイプ特異的な神経生理学的解析
2013 - 2016 オレキシン神経の直接の下流で睡眠・覚醒を制御する神経回路の同定・解析
2013 - 2015 オレキシン神経の直接の下流で睡眠・覚醒を制御する神経回路の同定・解析
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Papers (20):
Emi Hasegawa, Yulong Li, Takeshi Sakurai. Regulation of REM sleep in mice: The role of dopamine and serotonin function in the basolateral amygdala. Neuroscience Research. 2023
Takeshi Sakurai, Emi Hasegawa. Connecting the amygdala and dopamine: exploring the mysteries of rapid-eye movement sleep. SLEEP. 2023. 46. 8
Emi Hasegawa, Yo Oishi, Daniel Kroeger, Tomomi Tsunematsu, Yves Dauvilliers. Editorial: Neurobiology of sleeping behaviors. Frontiers in Behavioral Neuroscience. 2023. 17
Aki Takahashi, Romain Durand-de Cuttoli, Meghan E Flanigan, Emi Hasegawa, Tomomi Tsunematsu, Hossein Aleyasin, Yoan Cherasse, Ken Miya, Takuya Okada, Kazuko Keino-Masu, et al. Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice. Nature communications. 2022. 13. 1. 4039-4039
Tsuyoshi Saitoh, Mao Amezawa, Jumpei Horiuchi, Yasuyuki Nagumo, Naoshi Yamamoto, Noriki Kutsumura, Ryuichiro Ohshita, Akihisa Tokuda, Yoko Irukayama-Tomobe, Yasuhiro Ogawa, et al. Discovery of novel orexin receptor antagonists using a 1,3,5-trioxazatriquinane bearing multiple effective residues (TriMER) library. European journal of medicinal chemistry. 2022. 240. 114505-114505