Rchr
J-GLOBAL ID：201801017563929195
Update date: Feb. 27, 2024
Li Wei
リ ギ | Li Wei
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
https://www.lab.toho-u.ac.jp/phar/npcnm/
Research field (1)：
Environmental and pharmaceutical development resources
Research theme for competitive and other funds (9)：
- 2021 - 2024 Structure-Activity Relationship Study of Macrocyclic Daphnane Diterpenoids Towards Drug discovery for HIV Cure
- 2018 - 2021 Study on effectiveness of Kampo medicines for "negative" surrounding symptoms of dementia
- 2017 - 2020 Study on bioactive diterpenoids from medicinal plants of Thymelaeaceae and Euphorbiaceae families
- 2015 - 2018 Evaluation of Kampo Prescriptions as Therapeutic Agents for Glucose Metabolism Disorders
- 2014 - 2017 Phytochemical investigation of Daphnane-type diterpenoids aiming to discover next generation anti-HIV drugs
- 2013 - 2016 Investigation of new anti-cancer agents with selective anti-proliferative activities
- 2012 - 2015 Investigation of triterpenoid saponins from Ardisia plants with selective anti-proliferative activities against liver cancer cells
- 2011 - 2014 Discovery of novel natural PTP1B inhibitors as antidiabetes drug seeds
- 2006 - 2008 Chemical study on endangered medicinal plants in northeastern Region of China
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Papers (198)：
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Xueni Zhang, Xiaoyan Wen, Di Zhou, Yuhang Liang, Zhengqun Zhou, Gang Chen, Wei Li, Hao Gao, Ning Li. Lycibarbarspermidine L from the fruit of Lycium barbarum L. recovers intestinal barrier damage via regulating miR-195-3p. Journal of Ethnopharmacology. 2024
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Lingjian Tan, Kouharu Otsuki*, Mi Zhang, Takashi Kikuchi, Di Zhou, Ning Li, Li Huang, Chin-Ho Chen, Wei Li*. Daphnepedunins G and H, Anti-HIV Macrocyclic 3,4-seco-Daphnane Orthoesters from Daphne pedunculata. Journal of Natural Medicines. 2024. 78. 1
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Kouharu Otsuki*, Tsubasa Kobayashi, Kazuki Nakamura, Takashi Kikuchi, Li Huang, Chin-Ho Chen, Kazuo Koike, Wei Li*. LC-MS Identification, Isolation, and Structural Elucidation of Anti-HIV Macrocyclic Daphnane Orthoesters from Edgeworthia chrysantha. Fitoterapia. 2024. 172. 105731
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Mi Zhang, Kouharu Otsuki*, Reo Takahashi, Takashi Kikuchi, Di Zhou, Ning Li, Wei Li*. Identification of Daphnane Diterpenoids from Wikstroemia indica Using Liquid Chromatography with Tandem Mass Spectrometry. Plants. 2023. 12. 20. 3620
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Mi-xue Zhao, Jing Cai, Ying Yang, Jian Xu, Wen-yuan Liu, Toshihiro Akihisa, Wei Li, Takashi Kikuchi, Feng Feng, Jie Zhang. Traditional uses, chemical composition and pharmacological activities of Alstonia R. Br. (Apocynaceae): A review. Arabian Journal of Chemistry. 2023. 16. 8. 104857-104857
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MISC (8)：
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中瀬古 寛子, 李 巍, 長澤 美帆子, 田中 耕一郎, Gotov Choijamts, Purevjav Batkhuyag, Chultemsuren Yeruult, Nyambayar Khaliun, Dorjsuren Narantungalag, 内藤 篤彦, et al. モンゴル薬用植物Adonis mongolicaの心血管系に対する薬理作用. 応用薬理. 2018. 94. 5-6. 111-111
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W. Li, T. Sasaki, T. Onoda, K. Higai, K. Koike. Discovery of novel protein tyrosine phosphatase 1B inhibitors from medicinal plant resources. PLANTA MEDICA. 2016. 82
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李 巍, 菅野 裕一朗, 谷津 智史, 今井 美由紀, 鹿島 真奈美, 井上 義雄, 根本 清光, 小池 一男. 生薬沢瀉由来のプロトスタン型トリテルペンの核内受容体PXRアゴニスト活性. 日本生薬学会年会講演要旨集. 2015. 62回. 67-67
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谷津 智史, 菅野 裕一朗, 鹿島 真奈美, 劉 洋華, 李 巍, 小池 一男, 井上 義雄. Alisma plantagoaquatica含有成分のpregnane X receptor(PXR)アゴニスト作用. 日本薬学会年会要旨集. 2014. 134年会. 3. 118-118
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Chemical Components, Bioactivities, and Utilization of Health Foods from Lycium species. 2013. 218. 2. 166-172
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Books (2)：
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実践漢方生薬学
京都廣川書店 2020 ISBN:9784909197665
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資源天然物化学
共立出版 2017 ISBN:9784320044524
Lectures and oral presentations (52)：
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Anti-HIV macrocyclic daphnane orthoesters from <I>Edgeworthia chrysantha</I>
(The IUPAC 31st International Symposium on the Chemistry of Natural Products and the 11th International Congress on Biodiversity (ISCNP31 and ICOB11) 2023)
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ヒラタケ属キノコ由来の変形型ステロイドの探索研究
(第24回 天然薬物の開発と応用シンポジウム 2023)
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LC-MSを用いたジンチョウゲ科植物<I>Daphne pedunculata</I>に含まれるダフナン型ジテルペノイドの成分解析
(第69回日本生薬学会 2023)
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LC-MS を用いたマコモ根茎の化学成分解明
(第69回日本生薬学会 2023)
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LC-MSによるジンチョウゲ科アオガンピ属植物<I>Wikstroemia stenophylla</I>に含まれるジテルペノイドの解析
(第69回日本生薬学会 2023)
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Work history (3)：
- 2021/04 - 現在 Toho University Faculty of Pharmaceutical Sciences Faculty of Pharmaceutical Sciences Professor
- 2009/03 - 2021/03 Toho University Faculty of Pharmaceutical Sciences Faculty of Pharmaceutical Sciences Associate Professor
- 2004/04 - 2009/02 Toho University Faculty of Pharmaceutical Sciences Faculty of Pharmaceutical Sciences Lecturer
Committee career (3)：
- 2014/04 - 現在 日本生薬学会 学会誌編集委員
- 2023/03 - 2024/03 日本薬学会 代議員
- 2020/04 - 2023/03 日本薬学会 学会誌編集委員
Awards (4)：
- 2022/02 - 一般財団法人イスクラワクチン・医療基金 第46回「漢方研究」イスクラ奨励賞 「温故知新」伝統薬物の化学成分研究
- 2018/09 - 東邦大学 東邦大学教育賞
- 2016/09 - 日本生薬学会 日本生薬学会2016年学術振興賞
- 2009/09 - 日本生薬学会2009年学術奨励賞
Association Membership(s) (3)：
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