Hideo Nishitani

Affiliation and department：

Research field (1)： Molecular biology

Research theme for competitive and other funds (22)：

2020 - 2023 Mechanism of DNA synthesis-activated proteolysis for genome integrity
2014 - 2018 Regulation of DNA replication through proteolysis coupled with PCNA cycle
2014 - 2017 Coupling of spindle checkpoint with initiation of DNA replication
2013 - 2015 修復と複製時に機能するCul4-DDB1-Cdt2によるゲノム維持機構
2011 - 2013 M期DNA損傷の修復系とDNA複製開始制御の連係機構の解析

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Papers (86)：

Muadz Ahmad Mazian, Kumpei Yamanishi, Mohd Zulhilmi Abdul Rahman, Menega Ganasen, Hideo Nishitani. CRL4Cdt2 Ubiquitin Ligase, A Genome Caretaker Controlled by Cdt2 Binding to PCNA and DNA. Genes. 2022. 13. 2. 266-266
Andreas Panagopoulos, Stavros Taraviras, Hideo Nishitani, Zoi Lygerou. CRL4Cdt2: Coupling Genome Stability to Ubiquitination. Trends in Cell Biology. 2020. 30. 4. 290-302
Mazian M, Suenaga N, Ishii T, Hayashi A, Shiomi Y, Nishitani H. A DNA-binding domain in the C-terminal region of Cdt2 enhances the DNA synthesis-coupled CRL4Cdt2 ubiquitin ligase activity for Cdt1. J Biochem. 2019. 65. 6. 505-516
Gareth S. A. Wright, Akane Saeki, Takaaki Hikima, Yoko Nishizono, Tamao Hisano, Misaki Kamaya, Kohei Nukina, Hideo Nishitani, Hiro Nakamura, Masaki Yamamoto, et al. Architecture of the complete oxygen-sensing FixL-FixJ two-component signal transduction system. Science Signaling. 2018. 11. 525
Kohei Nukina, Akiyo Hayashi, Yasushi Shiomi, Kaoru Sugasawa, Motoaki Ohtsubo, Hideo Nishitani. Mutations at multiple CDK phosphorylation consensus sites on Cdt2 increase the affinity of CRL4Cdt2 for PCNA and its ubiquitination activity in S phase. Genes to Cells. 2018. 23. 3. 200-213

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MISC (7)：

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Education (3)：

Professional career (1)：

Work history (6)：

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