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J-GLOBAL ID:201801017657794196   Update date: Feb. 18, 2025

Hideo Nishitani

Hideo Nishitani
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Affiliation and department:
Research field  (1): Molecular biology
Research theme for competitive and other funds  (22):
  • 2020 - 2023 Mechanism of DNA synthesis-activated proteolysis for genome integrity
  • 2014 - 2018 Regulation of DNA replication through proteolysis coupled with PCNA cycle
  • 2014 - 2017 Coupling of spindle checkpoint with initiation of DNA replication
  • 2013 - 2015 修復と複製時に機能するCul4-DDB1-Cdt2によるゲノム維持機構
  • 2011 - 2013 M期DNA損傷の修復系とDNA複製開始制御の連係機構の解析
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Papers (87):
  • Yasushi Shiomi, Akiyo Hayashi, Yuichiro Saito, Masato T Kanemaki, Hideo Nishitani. The Depletion of TRAIP Results in the Retention of PCNA on Chromatin During Mitosis Leads to Inhibiting DNA Replication Initiation. Genes to cells : devoted to molecular & cellular mechanisms. 2025. 30. 2. e70006
  • Muadz Ahmad Mazian, Kumpei Yamanishi, Mohd Zulhilmi Abdul Rahman, Menega Ganasen, Hideo Nishitani. CRL4Cdt2 Ubiquitin Ligase, A Genome Caretaker Controlled by Cdt2 Binding to PCNA and DNA. Genes. 2022. 13. 2. 266-266
  • Andreas Panagopoulos, Stavros Taraviras, Hideo Nishitani, Zoi Lygerou. CRL4Cdt2: Coupling Genome Stability to Ubiquitination. Trends in Cell Biology. 2020. 30. 4. 290-302
  • Mazian M, Suenaga N, Ishii T, Hayashi A, Shiomi Y, Nishitani H. A DNA-binding domain in the C-terminal region of Cdt2 enhances the DNA synthesis-coupled CRL4Cdt2 ubiquitin ligase activity for Cdt1. J Biochem. 2019. 65. 6. 505-516
  • Gareth S. A. Wright, Akane Saeki, Takaaki Hikima, Yoko Nishizono, Tamao Hisano, Misaki Kamaya, Kohei Nukina, Hideo Nishitani, Hiro Nakamura, Masaki Yamamoto, et al. Architecture of the complete oxygen-sensing FixL-FixJ two-component signal transduction system. Science Signaling. 2018. 11. 525
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MISC (7):
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Education (3):
  • Kyushu University
  • Kyushu University
  • Kyoto University Faculty of Science
Professional career (1):
  • Doctor of Science (Kyushu University)
Work history (6):
  • 2020/04 - 現在 兵庫県立大学大学院理学研究科
  • 2007/04 - 現在 University of Hyogo of Life Science, Graduate School
  • 1997 - 2007/03 Kyushu University
  • 1993 - 1997 英国ガン研究基金研究所(ICRF) Cell Cycle lab 博士研究員
  • 1991 - 1992 日本学術振興会 特別研究員
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