Tsukiji Shinya

ツキジシンヤ | Tsukiji Shinya

Affiliation and department：
Job title： Professor
Homepage URL (2)： http://tsukijilab.web.nitech.ac.jp/index.html , http://tsukijilab.web.nitech.ac.jp/index-e.html

Research field (3)： Molecular biochemistry , Chemical biology , Biochemistry

Research keywords (3)： Chemical Biology , Biomolecular Chemistry , 合成生物学

Research theme for competitive and other funds (14)：

2021 - 2026 超高感度バイオマーカー・ウイルス検出を実現する人工細胞センサーのボトムアップ構築
2021 - 2024 生細胞内メンブレンコンタクトの可視化・操作ツールの開発
2020 - 2022 Development of a versatile chemogenetic protein inactivation method
2020 - 2022 細胞内オルガネラ膜結合分子の拡張とin vivo展開
2018 - 2021 Development of a method to control endogenous proteins by integrating genome editing and chemogenetic techniques

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Papers (86)：

Kai Tahara, Akinobu Nakamura, Xiaotong Wang, Keishi Mitamura, Yuki Ichihashi, Keiko Kano, Emi Mishiro-Sato, Kazuhiro Aoki, Yasuteru Urano, Toru Komatsu, et al. γ-Secretase Cleaves Bifunctional Fatty Acid-Conjugated Small Molecules with Amide Bonds in Mammalian Cells. ACS Chemical Biology. 2024
Eriko Deguchi, Shuhao Lin, Daiki Hirayama, Kimiya Matsuda, Akira Tanave, Kenta Sumiyama, Shinya Tsukiji, Tetsuhisa Otani, Mikio Furuse, Alexander Sorkin, et al. Low-affinity ligands of the epidermal growth factor receptor are long-range signal transmitters during collective cell migration of epithelial cells. Cell Reports. 2024. 43. 11. 114986
Kai Tahara, Akinobu Nakamura, Xiaotong Wang, Keishi Mitamura, Keiko Kano, Emi Mishiro-Sato, Yuki Ichihashi, Kazuhiro Aoki, Yasuteru Urano, Toru Komatsu, et al. γ-Secretase cleavages bifunctional fatty acid-conjugated small molecules with amide bonds in mammalian cells. ACS Chemical Biology. 2024. in press
Miyu Nagatani, Masaru Yoshikawa, Shinya Tsukiji, Masahiro Higuchi, Hitoshi Tamiaki, Shogo Matsubara. Acid-activatable photosensitizers for photodynamic therapy using self-aggregates of chlorophyll-peptide conjugates. Polymer Journal. 2024. in press
Moeka Ajiki, Masaru Yoshikawa, Tomoki Miyazaki, Asami Kawasaki, Kazuhiro Aoki, Fubito Nakatsu, Shinya Tsukiji. ORP9-PH domain-based fluorescent reporters for visualizing phosphatidylinositol 4-phosphate dynamics in living cells. RSC Chemical Biology. 2024

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MISC (38)：

築地真也. 細胞内シグナル分子の活性化を簡便・特異的・可逆的に誘導するSLIPT-PM法. 実験医学. 2024. 42. 11. 1750-1756
築地真也. 細胞内シグナル分子を特異的に活性化する新ツール "SLIPT". 生体の科学. 2023. 74. 6. 595-601
吉井達之, 築地真也. 光-化学遺伝学による細胞内タンパク質の局在操作. ケミカルバイオロジー. 2023. 16. 1. 7-9
築地真也. ケモジェネティクスによる細胞夾雑環境でのタンパク質活性操作. CSJカレントレビュー「生体分子環境の化学ー分子夾雑と1分子で解き明かす生体の挙動ー」. 2023. Part II. 9章. 86-92
築地真也, 鈴木祥央. SLIPT-PMシステムを用いた細胞内シグナル操作. 化学と工業. 2022. 75. 12. 879

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Patents (5)：

Education (3)：

Professional career (1)：

Work history (11)：

2019/10 - 現在名古屋大学, 未来社会創造機構ナノライフシステム研究所, 客員教授
2016/04 - 現在 Nagoya Institute of Technology Graduate School of Engineering
2016/04 - 現在 Nagoya Institute of Technology Graduate School of Engineering
2015/10 - 2016/03 Nagoya Institute of Technology Graduate School of Engineering
2015/04 - 2015/09 Nagaoka University of Technology Graduate School of Engineering, Department of Science of Technology Innovation

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Association Membership(s) (5)：

日本ペプチド学会 , 日本ケミカルバイロジー学会 , 日本化学会生体機能関連化学部会 , アメリカ化学会 , 日本化学会

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