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J-GLOBAL ID:201801017899801707   Update date: Mar. 30, 2025

Ooe Kazuhiro

オオエ カズヒロ | Ooe Kazuhiro
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Affiliation and department:
Research theme for competitive and other funds  (8):
  • 2024 - 2027 Development of innovative alpha therapy targeting cancer-associated fibroblasts
  • 2022 - 2025 加速器製造可能な新規セラノスティクス核種の開発
  • 2022 - 2025 悪性黒色腫の標的α線治療を指向するAt-211標識薬剤開発
  • 2019 - 2022 Development of At-211-labeled agents targeting the tumor hypoxia region
  • 2019 - 2022 Development of accelerator produced radionuclides for radioisotope therapy application
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Papers (88):
  • Hiroyuki Suzuki, Saki Yamashita, Shoko Tanaka, Kento Kannaka, Ichiro Sasaki, Yasuhiro Ohshima, Shigeki Watanabe, Kazuhiro Ooe, Tadashi Watabe, Noriko S. Ishioka, et al. An 211At-labeled alpha-melanocyte stimulating hormone peptide analog for targeted alpha therapy of metastatic melanoma. European Journal of Nuclear Medicine and Molecular Imaging. 2025
  • Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Kentaro Hisada, Sifan Feng, Yuichiro Kadonaga, Kazuhiro Ooe, Tadashi Watabe, Yoshiyuki Manabe, Atsushi Shimoyama, Masashi Murakami, et al. Development of LAT1-Selective Nuclear Medicine Therapeutics Using Astatine-211. International journal of molecular sciences. 2024. 25. 22
  • Kentaro Hisada, Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuichiro Kadonaga, Atsuko Saito, Tadashi Watabe, Sifan Feng, Kazuhiro Ooe, Xiaojie Yin, Hiromitsu Haba, et al. Comparison Length of Linker in Compound for Nuclear Medicine Targeting Fibroblast Activation Protein as Molecular Target. International journal of molecular sciences. 2024. 25. 22
  • Kaori Abe, Tadashi Watabe, Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuichiro Kadonaga, Sadahiro Naka, Kazuhiro Ooe, Atsushi Toyoshima, Frederik Giesel, Takeshi Usui, et al. Evaluation of Targeted Alpha Therapy Using [211At]FAPI1 in Triple-Negative Breast Cancer Xenograft Models. International journal of molecular sciences. 2024. 25. 21
  • Tadashi Watabe, Kazuko Kaneda-Nakashima, Yuichiro Kadonaga, Kazuhiro Ooe, Thosapol Sampunta, Naoki Hirose, Xiaojie Yin, Hiromitsu Haba, Yukiyoshi Kon, Atsushi Toyoshima, et al. Preclinical Evaluation of Biodistribution and Toxicity of [211At]PSMA-5 in Mice and Primates for the Targeted Alpha Therapy against Prostate Cancer. International journal of molecular sciences. 2024. 25. 11
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MISC (74):
  • 島本博彰, 加藤弘樹, 片山大輔, 角永悠一郎, 大江一弘, HUANG Xuhao, 下山敦史, 下山敦史, 樺山一哉, 樺山一哉, et al. Intratumoral administration of astatine-211-labeled gold nanoparticles for alpha-particle therapy: Antitumor effect for a mouse model of tongue cancer. 歯科放射線. 2024. 64
  • 大江一弘, 吉村崇. Analysis of iodine with a capillary electrophoresis method for speciation of astatine. 日本放射化学会討論会(Web). 2023. 67th
  • HUANG Xuhao, KATO Hiroki, KADONAGA Yuichiro, SHIMOYAMA Atsushi, KABAYAMA Kazuya, KATAYAMA Daisuke, OOE Kazuhiro, TOYOSHIMA Atsushi, SHINOHARA Atsushi, FUKASE Koichi. Synthesis and evaluation of astatine-211 labeled gold nanoparticles for alpha nano-brachytherapy. 日本化学会春季年会講演予稿集(Web). 2021. 101st
  • HUANG Xuhao, 加藤弘樹, 角永悠一郎, 下山敦史, 樺山一哉, 片山大輔, 大江一弘, 豊嶋厚史, 羽場宏光, WANG Yang, et al. Synthesis and Evaluation of At-211 Labeled Gold Nanoparticles for Alpha Brachytherapy. 日本放射化学会討論会(Web). 2021. 65th
  • 加藤弘樹, 片山大輔, 大江一弘, 角永悠一郎, 黄栩昊, 下山敦史, 樺山一哉, 深瀬浩一, 畑澤順. 局所投与による癌増殖抑制のためのアスタチン標識金ナノ粒子の最適化. 核医学(Web). 2021. 58. Supplement
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