Inaguma Shingo

Affiliation and department：

Research field (2)： Human pathology , Experimental pathology

Research keywords (4)：消化器病理 , 腫瘍免疫 , 分子腫瘍学 , 病理学

Research theme for competitive and other funds (12)：

2023 - 2026 PBKリン酸化標的遺伝子を介した大腸癌悪性形質制御機構の解析と治療応用の可能性
2020 - 2023 Regulation of the tumor malignant potentials and immune evasion by CD70-positive stromal cells.
2016 - 2019 The analysis of the p53 isoforms in hepatocellular carcinoma cells using endogenous gene modification.
2017 - 2019 膵癌細胞におけるPD-L1発現と腫瘍幹細胞性・上皮間葉転換による悪性形質の解析
2015 - 2018 Downstream of newly identified transcriptional repressor and its role in the progression of non-invasive breast cancer.

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Papers (65)：

Maria Aoki, Taku Naiki, Aya Naiki-Ito, Toshiharu Morikawa, Nayuka Matsuyama, Koei Torii, Taiki Kato, Tetsuji Maruyama, Shingo Inaguma, Takahiro Yasui. Successful treatment with enfortumab-vedotin of metastatic signet ring cell cancer expressing nectin-4 and originating from the bladder. IJU Case Reports. 2023
Sunao Ito, Akira Koshino, Masayuki Komura, Shunsuke Kato, Takahiro Otani, Chengbo Wang, Akane Ueki, Hiroki Takahashi, Masahide Ebi, Naotaka Ogasawara, et al. Characterization of colorectal cancer by hierarchical clustering analyses of five immune cell markers. Pathology International. 2023
Shingo Inaguma, Akane Ueki, Jerzy Lasota, Masayuki Komura, Asraful Nahar Sheema, Piotr Czapiewski, Renata Langfort, Janusz Rys, Joanna Szpor, Piotr Waloszczyk, et al. CD70 and PD-L1 (CD274) co-expression predicts poor clinical outcomes in patients with pleural mesothelioma. The journal of pathology. Clinical research. 2023. 9. 3. 195-207
Akane Ueki, Masayuki Komura, Akira Koshino, Chengbo Wang, Kazuhiro Nagao, Mai Homochi, Yuki Tsukada, Masahide Ebi, Naotaka Ogasawara, Toyonori Tsuzuki, et al. Stromal POSTN Enhances Motility of Both Cancer and Stromal Cells and Predicts Poor Survival in Colorectal Cancer. Cancers. 2023. 15. 3
Małgorzata Chłopek, Jerzy Lasota, Lester D R Thompson, Magdalena Szczepaniak, Alina Kuźniacka, Kinga Hińcza, Kamila Kubicka, Maciej Kaczorowski, Michael Newford, Yalan Liu, et al. Alterations in key signaling pathways in sinonasal tract melanoma. A molecular genetics and immunohistochemical study of 90 cases and comprehensive review of the literature. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2022. 35. 11. 1609-1617

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MISC (5)：

伊藤直, 稲熊真悟, 小川了, 小村理行, 加藤寛之, 内木綾, 齋藤正樹, 上野修平, 早川俊輔, 大久保友貴, et al. 膵癌におけるテトラスパニンCD63の発現と臨床的意義. 日本外科学会定期学術集会抄録集. 2023. 123回. SF-1
Anna Felisiak-Golabek, Shingo Inaguma, Artur Kowalik, Bartosz Wasag, Zeng-Feng Wang, Jerzy Lasota, Markku M. Miettinen. SP174 Antibody Lacks Specificity for NRAS Q61R and Cross-Reacts with HRAS- and KRAS-Q61R Mutant Proteins in Malignant Melanoma. MODERN PATHOLOGY. 2017. 30. 128A-129A
Shingo Inaguma, Anna Felisiak-Golabek, Zengfeng Wang, Jerzy Lasota, Markku M. Miettinen. Mismatch Repair System Molecule Immunophenotype and BRAF V600E Genotype of PD-L1-Positive Primary and Metastatic Colorectal Carcinomas. MODERN PATHOLOGY. 2017. 30. 176A-176A
Shingo Inaguma, Kenji Kasai, Hiroshi Ikeda. GLI1 induces the expression of bHLH type transcriptional repressor DEC2 in pancreatic cancer cells. CANCER RESEARCH. 2010. 70
稲熊真悟, 小川久美子, 鈴木周五, 二口充, 白井智之. 18 trisomyに心血管奇形と消化管奇形を合併した一剖検例. 日本病理学会会誌. 2002. 91. 1. 249-249

Professional career (1)：

博士(医学) (名古屋市立大学)

Work history (6)：

2021/04 - 現在名古屋市立大学東部医療センター病理診断科教授
2019/10 - 2021/03 名古屋市立東部医療センター病理診断科部長
2019/10 - 2021/03 Nagoya City University
2011/02 - 2019/09 Aichi Medical University
2015/07 - 2016/09 National Cancer Institute/NIH Laboratory of Pathology Guest Researcher

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Awards (4)：

2016/05 - 日本病理学会学術奨励賞
2014/08 - 瑞友会(名古屋市立大学医学部同窓会) 第8回瑞友会賞
2013/12 - 公益財団法人日本膵臓病研究財団第21回膵臓病研究奨励賞
2011/12 - 財団法人膵臓病研究財団第19回膵臓病研究奨励賞

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