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J-GLOBAL ID：201801018254201027 Update date: Jan. 25, 2025

Ito Junya

イトウジュンヤ | Ito Junya

Affiliation and department：

Research field (3)： Food sciences , Applied biochemistry , Applied molecular and cellular biology

Research keywords (6)：食品機能分析学 , 過酸化脂質 , 食品化学 , 脂質生化学 , Ferroptosis , γ-オリザノール

Research theme for competitive and other funds (7)：

2024 - 2027 Molecular mechanisms of plant redox signaling that are mediated by reactive carbonyl species
2023 - 2026 生体・植物におけるトリテルペン関連化合物の代謝・生合成経路の解明
2022 - 2024 Identification of responsible oxidized lipids in ferroptosis triggering and development of the prevention with food functional ingredients
2021 - 2023 Elucidation of the mechanisms of oxidative modification of skin lipids using LC-MS/MS and the development of control method by food functional ingredients
2019 - 2021 Elucidation of the in vivo absorption and metabolism of g-oryzanol (OZ) and the biosynthetic pathway of OZ in plants

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Papers (78)：

Junya Ito, Naoko Kumagai, Ayaka Suzuki, Naoki Shoji, Isabella Supardi Parida, Mamoru Takahashi, Kiyotaka Nakagawa. Effect of microemulsion system on water dispersibility and bioavailability of γ-oryzanol. Bioscience, biotechnology, and biochemistry. 2025
Yusuke Hirata, Yuto Yamada, Soma Taguchi, Ryota Kojima, Haruka Masumoto, Shinnosuke Kimura, Takuya Niijima, Takashi Toyama, Ryoji Kise, Emiko Sato, et al. Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondria. Cell death & disease. 2024. 15. 12. 884-884
Junya Ito, Toshitaka Nakamura, Takashi Toyama, Deng Chen, Carsten Berndt, Gereon Poschmann, André Santos Dias Mourão, Sebastian Doll, Mirai Suzuki, Weijia Zhang, et al. PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization. Molecular cell. 2024. 84. 23. 4629-4644
Isabella Supardi Parida, Soo Takasu, Junya Ito, Takahiro Eitsuka, Kiyotaka Nakagawa. 1-Deoxynojirimycin attenuates pathological markers of Alzheimer's disease in the in vitro model of neuronal insulin resistance. The FASEB Journal. 2024. 38. 13
Naoya Yamada, Tadayoshi Karasawa, Junya Ito, Daisuke Yamamuro, Kazushi Morimoto, Toshitaka Nakamura, Takanori Komada, Chintogtokh Baatarjav, Yuma Saimoto, Yuka Jinnouchi, et al. Inhibition of 7-dehydrocholesterol reductase prevents hepatic ferroptosis under an active state of sterol synthesis. Nature communications. 2024. 15. 1. 2195-2195

MISC (125)：

中溝莉緒, 高須蒼生, PARIDA Isabella Supardi, 伊藤隼哉, 鈴木誠一郎, 須藤圭一, 江坂幸宏, 木村俊之, 仲川清隆. Isolation and identification of aza-sugars in a mulberry family leaf by LC-MS/MS. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
高須蒼生, 中溝莉緒, SUPARDI Parida Isabella, 伊藤隼哉, 鈴木誠一郎, 須藤圭一, 江坂幸宏, 江坂幸宏, 木村俊之, 仲川清隆. イオンモビリティー質量分析でのイミノ糖立体異性体の分析. 日本分析化学会年会講演要旨集(Web). 2023. 72nd
重松孝暢, 高田朋之, 乙木百合香, 伊藤隼哉, 加藤俊治, 横山光子, 松本哲哉, 江藤淳, 仲川清隆. Relationship between water activity and lipid oxidation: Involvement of Maillard reaction or not. 日本メイラード学会年会プログラム・抄録集. 2023. 33rd
PARIDA Isabella Supardi, 高須蒼生, 伊藤隼哉, 永塚貴弘, 仲川清隆. 1-Deoxynojirimycin alleviates neuronal insulin resistance and tau hyperphosphorylation in-vitro. 日本食品科学工学会大会講演集. 2022. 69th
手嶋琢, 中沢威人, 内海俊彦, 伊藤隼哉, 向井裕美, 仲川清隆, 本田与一, 松井健二. Basidiomycete dioxygenase is essential for forming 1-octen-3-ol, a major volatile of mushrooms. 日本きのこ学会大会講演要旨集. 2022. 25th

Patents (2)：

Books (3)：

Lectures and oral presentations (246)：

Study of the acidic compounds derived from triacylglycerol that contribute to acid value increment
(22nd IUNS-International Congress of Nutrition 2022)
Elucidation of novel γ-oryzanol species in rice bran oil and processed foods containing rice bran oil
(22nd IUNS-International Congress of Nutrition 2022)
Water in oil emulsion system modifies absorption profile of green tea catechins in the body and also masks their bitter taste: Evaluation in human subjects
(22nd IUNS-International Congress of Nutrition 2022)
The absorption and metabolism of γ-oryzanol, a functional compound characteristic of rice bran, is different depending on its molecular species
(22nd IUNS-International Congress of Nutrition 2022)
Bioactive iminosugar 1-deoxynojirimycin reverses neuronal insulin resistance and alleviates tau hyperphosphorylation: an in vitro study using insulin-resistant neuroblastoma
(22nd IUNS-International Congress of Nutrition 2022)

Professional career (1)：

Work history (5)：

Association Membership(s) (10)：

日本食品科学工学会 , 日本香粧品学会 , 日本ビタミン学会 , 日本メイラード学会 , 日本脂質栄養学会 , 日本脂質生化学会 , 日本生化学会 , 日本油化学会 , 日本栄養・食糧学会 , 日本農芸化学会

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