Rchr
J-GLOBAL ID：201801018597124060
Update date: May. 04, 2024
Hashimoto Koji
ハシモト コウジ | Hashimoto Koji
Affiliation and department：
Job title：
Assistant Professor
Research field (2)：
Molecular biology
, Applied biochemistry
Research keywords (4)：
Antibody Engineering
, Biotechnolgy
, Nucleic acid chemistry
, Synthetic biology
Research theme for competitive and other funds (2)：
- 2023 - 2025 修飾RNAに応答する合成大腸菌系の作製とそれを利用した修飾mRNA転写酵素の創製
- 2021 - 2024 細胞内人工核酸複製系の開発
Papers (6)：
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Koji Hashimoto, Emil C. Fischer, Floyd E. Romesberg. Efforts toward Further Integration of an Unnatural Base Pair into the Biology of a Semisynthetic Organism. Journal of the American Chemical Society. 2021. 143. 23. 8603-8607
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Emil C. Fischer, Koji Hashimoto, Yorke Zhang, Aaron W. Feldman, Vivian T. Dien, Rebekah J. Karadeema, Ramkrishna Adhikary, Michael P. Ledbetter, Ramanarayanan Krishnamurthy, Floyd E. Romesberg. New codons for efficient production of unnatural proteins in a semisynthetic organism. Nature Chemical Biology. 2020. 16. 5. 570-576
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Hashimoto K, Kurosawa K, Seo H, Ohta K. Rapid Chimerization of Antibodies. Methods in molecular biology (Clifton, N.J.). 2019. 1904. 307-317
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Takashi Hashimoto, Kwesi Teye, Koji Hashimoto, Katarzyna Wozniak, Daisuke Ueo, Sakuhei Fujiwara, Kazuhiro Inafuku, Yorihisa Kotobuki, Ines Lakos Jukic, Branka Marinović, et al. Clinical and Immunological Study of 30 Cases With Both IgG and IgA Anti-Keratinocyte Cell Surface Autoantibodies Toward the Definition of Intercellular IgG/IgA Dermatosis. Frontiers in immunology. 2018. 9. 994-994
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Kwesi Teye, Koji Hashimoto, Sanae Numata, Kunihiro Ohta, Marek Haftek, Takashi Hashimoto. Multimerization is required for antigen binding activity of an engineered IgM/IgG chimeric antibody recognizing a skin-related antigen. Scientific Reports. 2017. 7. 1
ｍore...
MISC (3)：
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橋本講司. 領域展開の合成生物学. 生物工学会誌. 2023. 101. 8. 450
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橋本講司, 黒澤恒平, 村山晃歩, 瀬尾秀宗, 太田邦史. 免疫系培養細胞を利用した抗体の分子進化工学. 日本生化学会大会(Web). 2017. 2017年度. [1P-1361]
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瀬尾秀宗, 橋本講司, 村山晃歩, 黒澤恒平, 太田邦史. 染色体弛緩による相同組換え活性化を利用した新規抗体作製技術ADLibシステム. 日本生化学会大会(Web). 2017. 2017年度. [2PW03-6]
Patents (1)：
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COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES
Lectures and oral presentations (8)：
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Expanding the Genetic Code: Characterization and Application of Unnatural Codons in Semisynthetic Organisms
(2023)
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人工塩基対で大腸菌をプログラムする
(2023)
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Bicoastal Research
(2022 Annual Meeting of The Japan Scripps Society East Division 2022)
-
人工核酸適応型大腸菌システムの構築
(第16回バイオ関連化学シンポジウム 2022)
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Engineering Semisynthetic Organisms using Unnatural Base Pairs
(ISNAC2021 2021)
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Education (2)：
- 2012 - 2017 The University of Tokyo Graduate School of Arts and Sciences Multi-Disciplinary Sciences Life Sciences
- 2008 - 2012 The University of Tokyo College of Arts and Sciences Department of Life and Cognitive Sciences
Professional career (1)：
- PhD (The University of Tokyo)
Work history (5)：
- 2022/09 - 現在 The University of Tokyo Graduate School of Arts and Sciences Assistant Professor
- 2021/06 - 2022/08 Nagoya University Graduate School of Science JSPS Postdoctoral Fellow
- 2020/02 - 2021/05 The Scripps Research Institute Department of Immunology and Microbiology Postdoctoral Fellow
- 2018/04 - 2020/01 The Scripps Research Institute Department of Chemistry Postdoctoral Fellow
- 2017/04 - 2018/03 The University of Tokyo Graduate School of Arts and Sciences Project Researcher
Committee career (1)：
- 2023/09 - 現在 Young Researchers Committee for Biotechnology Homepage and Forum
Awards (5)：
- 2021/04 - 日本学術振興会 特別研究員(PD)
- 2019/07 - 最優秀ポスター賞 生物工学若手会
- 2019/02 - 日本学術振興会 海外特別研究員
- 2018/02 - 東洋紡バイオテクノロジー研究財団 平成29年度長期研究助成
- 2016/11 - 第39回日本分子生物学会年会 ポスター賞
Association Membership(s) (4)：
The Antibody Society of Japan
, 日本化学会
, ケミカルバイオロジー学会
, 日本化学会生体機能関連化学部会
