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J-GLOBAL ID：201801019343895772   Update date: Feb. 25, 2025

Matsumoto Sakiko

マツモト サキコ | Matsumoto Sakiko
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Affiliation and department：
Osaka Metropolitan University Graduate School of Medicine Department of Basic Medical Science

About Osaka Metropolitan University Graduate School of Medicine Department of Basic Medical Science


Job title： Lecturer
Research field  (1)： Medical biochemistry
Research keywords  (1)： 神経科学、神経発生、神経変性、微小管
Research theme for competitive and other funds  (3)：
  • 2019 - 2022 脱リン酸化酵素PP4c欠損による中枢神経変性のメカニズム解明
  • 2017 - 2019 微小管モータータンパク質制御因子NudCの神経系における機能解析
  • 2012 - 2015 神経再生関連分子の機能解析
Papers (11)：
  • Jin M, Matsumoto S, Ayaki T, Yamakado H, Taguchi T, Togawa N, Konno A, Hirai H, Nakajima H, Komai S, et al. DOPAnization of tyrosine in α-synuclein by tyrosine hydroxylase leads to the formation of oligomers. Nature communications. 2022. 13. 1. 6880
  • Shengming Wang, Yu Fu, Takaki Miyata, Sakiko Matsumoto, Tomoyasu Shinoda, Kyoko Itoh, Akihiro Harada, Shinji Hirotsune, Mingyue Jin. Functional Cooperation of α-Synuclein and Tau Is Essential for Proper Corticogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022. 42. 37. 7031-7046
  • Kaneko A, Kiryu-Seo S, Matsumoto S, Kiyama H. Correction: Damage-induced neuronal endopeptidase (DINE) enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury. Cell death & disease. 2020. 11. 7. 541
  • Shiori Toba, Mingyue Jin, Masami Yamada, Kanako Kumamoto, Sakiko Matsumoto, Takuo Yasunaga, Yuko Fukunaga, Atsuo Miyazawa, Sakiko Fujita, Kyoko Itoh, et al. Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport. Scientific Reports. 2017. 8. 1. 8019
  • Shiori Toba, Mingyue Jin, Masami Yamada, Kanako Kumamoto, Sakiko Matsumoto, Takuo Yasunaga, Yuko Fukunaga, Atsuo Miyazawa, Sakiko Fujita, Kyoko Itoh, et al. Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport. SCIENTIFIC REPORTS. 2017. 7. 1. 16386
ｍore...
MISC (1)：
Lectures and oral presentations  (12)：
  • チロシンヒドロキシラーゼによるαシヌクレインのドーパ化修飾は中脳黒質ニューロンの細胞死を促進する
    (2025)
  • α-synuclein is post-translationally modified by tyrosine hydroxylase in Parkinson’s disease, leading to a dopaminergic neurodegeneration.
    (Neuro2024 2024)
  • パーキンソン病において形成されるDOPA化αシヌクレインの高感度検出法の確立
    (日本生化学会大会プログラム・講演要旨集 2023)
  • ドーパミン作動性ニューロンに発現するチロシンヒドロキシラーゼは、αシヌクレインを翻訳後修飾してオリゴマーの形成を促進する
    (第45回 日本分子生物学会 2022)
  • New posttranslational modification of α-synuclein by tyrosine hydroxylase is a potential pathogenesis of Parkinson’s disease.
    (2022)
ｍore...
Professional career (3)：
  • PhD (Nagoya University)
  • 学士(人間科学) (大阪大学)
  • 修士(医科学) (大阪市立大学)
Work history (5)：
  • 2023/04 - 現在 Osaka Metropolitan University School of Medicine Department of Medical Science Lecturer
  • 2023/04 - 現在 Osaka Metropolitan University Graduate School of Medicine Department of Basic Medical Science Lecturer
  • 2016/07/01 - 現在 Osaka City University Graduate School of Medicine Basic Medicine Course Assistant Professor
  • 2022/04 - 2023/03 Osaka Metropolitan University Graduate School of Medicine Department of Basic Medical Science Assistant Professor
  • 2015/04 - 2016/06 名古屋大学大学院 医学系研究科 研究員(非常勤)
Awards (2)：
  • 2023/06 - 公益財団法人大阪難病研究財団 第5回藪本秀雄賞
  • 2023/03 - 大阪公立大学医学部 医学部長賞奨励賞
Association Membership(s) (4)：
日本解剖学会 ,  日本神経化学会 ,  日本分子生物学会 ,  日本生化学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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