Iizasa Ei'ichi

イイザサエイイチ | Iizasa Ei'ichi

Affiliation and department：
Homepage URL (1)： http://www2.kufm.kagoshima-u.ac.jp/field/health-research/f003/02.html

Research field (3)： Molecular biology , Plants: molecular biology and physiology , Immunology

Research keywords (4)： Gap repair cloning , yeast homologous recombination , pattern recognition receptor , immunology

Research theme for competitive and other funds (16)：

2024 - 2027 がん悪液質における視床下部炎症の新規分子基盤解明
2024 - 2026 IL-3, IL-5受容体下流におけるITAM分子シグナルの機能解明とアレルギー喘息へのその寄与
2024 - 2026 鹿児島特産シナモンと白麹の抗ストレス・肥満効果の分子基盤解明とヒトでの効果検証
2024 - 2025 サンケイ科学振興財団研究助成
2020 - 2023 Elucidation of the role of ITAM-Card9 pathway in beta c cytokine receptor signaling

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Papers (22)：

Hideo Mitsuyama, Ei'ichi Iizasa, Akiko Kukita, Shuji Toda, Hiroki Yoshida, Hiromasa Inoue, Hiromitsu Hara. Deletion of Card9 eliminates the detrimental facets of mycobacterial adjuvants. Heliyon. 2024
Ei’ichi Iizasa, Haruki Iwai, Youki Oyamada, Kaori Hamashima, Ryusei Nishi, Koji Ataka, Haruka Amitani, Kousaku Ohinata, Ikuo Kato, Akihiro Asakawa. A plant-derived δ opioid receptor agonist rubiscolin-6 ameliorates sickness behavior in mice with cancer cachexia. Journal of Functional Foods. 2024
Youki Oyamada, Ei'ichi Iizasa, Amane Usa, Konosuke Otomaru. 1,25-Dihydroxyvitamin D₃ potentiates the innate immune response of peripheral blood mononuclear cells from Japanese Black cattle. Animal Science Journal. 2023. 94. 1
Ei'ichi Iizasa, Yasushi Chuma, Takayuki Uematsu, Mio Kubota, Hiroaki Kawaguchi, Masayuki Umemura, Kenji Toyonaga, Hideyasu Kiyohara, Ikuya Yano, Marco Colonna, et al. TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation. Nature communications. 2021. 12. 1. 2299-2299
Mio Kubota, Ei'ichi Iizasa, Yasushi Chuuma, Hideyasu Kiyohara, Hiromitsu Hara, Hiroki Yoshida. Adjuvant activity of Mycobacteria-derived mycolic acids. Heliyon. 2020. 6. 5. e04064

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MISC (7)：

飯笹英一. 大学から地域へ。学びの意欲と科学リテラシーを育む教育ーサイエンスカフェを通してー. 教育研究情報. 2018. 50. 76-81
原博満, 飯笹英一, 清原秀泰, 中馬康志, 梅村正幸, 山崎晶, 松崎吾朗, 吉田裕樹. アルツハイマー病脳内炎症の中核機構に迫る ITAM共役型受容体による抗酸菌脂質の認識と自然免疫応答の制御. Dementia Japan. 2017. 31. 4. 505-505
Toyonaga K, Iizasa E, Hara H. Ligand-recognition and innate immune response through ITAM/ITIM-coupled pattern recognition receptors. Clinical immunology & allergology. 2016. 66. 3. 274-282
永野幸生, 飯笹英一. 相同組換えで色々できちゃうDNAクローニング. 生物工学会誌. 2015. 93. 10. 623-626
Mio Kubota, Ei'ichi Iizasa, Hideyasu Kiyohara, Yasushi Nakama, Hiromitsu Hara, Hiroki Yoshida. Mycobacterium tuberculosis-derived mycolic acid shows an adjuvant activity by activation of the ITAM receptor/CARD9-mediated innate immunity. CYTOKINE. 2014. 70. 1. 78-78

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Patents (1)：

Books (1)：

Lectures and oral presentations (26)：

FcRγ-Card9 signaling activated by GM-CSF facilitates the differentiation of bone marrow-derived macrophages induced by GM-CSF
(The 1st Annual Meeting of Japanese Cytokine Society 2024)
Card9 is crucial for bone marrow-derived inflammatory macrophage differentiation induced by GM-CSF
(The 50th Annual Meeting of the Japanese Society for Immunology 2021)
TREM2は非糖鎖付加ミコール酸を認識し、抗結核免疫応答を抑制する
(第32回日本生体防御学会学術総会 2021)
TREM2は非糖鎖付加ミコール酸を認識し、マクロファージの抗酸菌免疫応答を抑制する
(第85回日本インターフェロン・サイトカイン学会 2021)
結核菌脂質ミコール酸を認識するパターン認識受容体とその免疫制御
(第43回蛋白質と酵素の構造と機能に関する九州シンポジウム 2019)

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Education (3)：

2007 - 2010 Kagoshima University United Graduate School of Agricultural Sciences
2005 - 2007 Saga University Master Course of Agriculture
2001 - 2005 Saga University Faculty of Agriculture

Professional career (1)：

Work history (5)：

2015/01 - 現在 Kagoshima University Graduate School of Medical and Dental Sciences
2014/04 - 2014/12 Saga University Faculty of Medicine
2011/04 - 2014/03 日本学術振興会特別研究員(PD)
2010/04 - 2011/03 佐賀大学健康プロジェクト博士研究員
2007/04 - 2010/03 日本学術振興会特別研究員(DC1)

Awards (10)：

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Association Membership(s) (5)：

日本抗体学会 , 日本生体防御学会 , 日本インターフェロン・サイトカイン学会 , JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY , THE JAPANESE SOCIETY FOR IMMUNOLOGY

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