Rchr
J-GLOBAL ID：201801020019724351   Update date: Apr. 22, 2024

Yanagisawa Hiromi

ヤナギサワ ヒロミ | Yanagisawa Hiromi
Affiliation and department：
University of Tsukuba Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)

About University of Tsukuba Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)


Job title： Professor
Homepage URL  (1)： https://www.saggymousehkytsukuba.com
Research field  (4)： Pathobiochemistry ,  Cardiovascular surgery ,  Medical biochemistry ,  Cardiology
Research keywords  (21)： Elastin ,  matricellular proteins ,  fibulins ,  glycans ,  Genetic engineering ,  disease mouse model ,  aging ,  cerebrovascular system ,  tissue stem cell ,  Raman Imaging ,  biomechanics ,  elastic fibers ,  vascular remodeling ,  mechanobiology ,  vascular biology ,  heritable thoracic aortic disease (HTAD) ,  vascular injury and vascular remodeling ,  aortic aneurysm ,  extracellular matrix ,  extracellular microenvironment ,  Aortic Dissection
Research theme for competitive and other funds  (29)：
  • 2023 - 2027 Elucidation of the mechanism of thoracic aortic disease based on extracellular matrix and development of novel therapeutic strategy
  • 2021 - 2025 Elucidation of the pathogenesis of aortic dissection caused by the alteration in microfibrils
  • 2023 - 2024 メカノセンシング機構の破綻による大動脈疾患の病態解明とバイオマーカー診断法の開発
  • 2023 - 2024 新規大動脈解離マウスモデルを用いたマルファン症候群等類縁疾患の大動脈解離発症機序の解明
  • 2020 - 2024 上皮幹細胞コンパートメントを規定する分子機構と生物学的意義の解明
Show all
Papers (114)：
  • Torimoto, Keiichi, Elliott, Katherine, Nakayama, Yuki, Yanagisawa, Hiromi, Eguchi, Satoru. Cardiac and perivascular myofibroblasts, matrifibrocytes, and immune fibrocytes in hypertension; commonalities and differences with myocardial infarction and other cardiovascular diseases. Cardiovascular research. 2024
  • Violette, Deleeuw, Carlson, Eric, Renard, Marjolijn, Zientek, Keith D, Wilmarth, Phillip A, Reddy, Ashok P, Manalo, Elise C, Tufa, Sara F, Keene, Douglas R, Olbinado, Margie, et al. Unraveling the Role of TGFβ Signaling in Thoracic Aortic Aneurysm and Dissection Using Fbn1 Mutant Mouse Models. MATRIX BIOLOGY. 2023. 123. 17-33
  • Raja, Erna, Clarin, Maria Thea, Rane, Dela Cruz, Yanagisawa, Hiromi. Matricellular Proteins in the Homeostasis, Regeneration, and Aging of Skin. Int J Mol Sci. 2023. 24. 18. 14274
  • Nguyen, Tram Anh Vu, Lino, Caroline Antunes, Hang, Huynh Thuy, Alves, Juliano Vilela, Thang, Bui Quoc, Shin, Seung Jae, Sugiyama, Kaori, Matsunaga, Hiroko, Takeyama, Haruko, et al. Protective Role of Endothelial Fibulin-4 in Valvulo-Arterial Integrity. Journal of the American Heart Association. 2023. 12. 1
  • Yamashiro, Yoshito, Ramirez, Karina, Nagayama, Kazuaki, Hattori, Naoko, Liu, Yu-Yu, Matsunaga, Shinji, Tomita, Shuhei, Kubota, Yoshiaki, Yanagisawa, Hiromi. Partial endothelial-to-mesenchymal transition mediated by HIF-induced CD45 in neointima formation upon carotid artery ligation. Cardiovascular research. 2022
ｍore...
MISC (12)：
  • 柳沢裕美, 中邨智之. 血管におけるマトリクスエイジング. バイオマテリアルー生体材料ー. 2020. 38. 3. 172-177
  • 船戸 紀子, Srivastava Deepak, Yanagisawa Hiromi. 転写因子Tbx1はヒト口蓋裂の疾患遺伝子の発現調節により口蓋の発生に関与する. Journal of Oral Biosciences Supplement. 2018. 2018. 407-407
  • Tomoko Okuyama, Jun Shirakawa, Hiromi Yanagisawa, Yasuo Terauchi. Identification of Matricellular Protein Fibulin-5 as a Target Molecule of Glucokinase-Mediated Calcineurin/NFAT Signaling in Pancreatic Islets. DIABETES. 2017. 66. A584-A584
  • Tomoko Okuyama, Jun Shirakawa, Hiromi Yanagisawa, Yasuo Terauchi. Fibulin5 Deficiency Improved Insulin Resistance and Hepatic Steatosis Induced by High-Fat Feeding. DIABETES. 2015. 64. A492-A493
  • Jacopo Ferruzzi, Matthew Bersi, Stuart Campbell, Hiromi Yanagisawa, Jay D. Humphrey. Characterization of central artery stiffness, hemodynamics, and left ventricular function in a mouse model of accelerated aging. ANGIOGENESIS. 2014. 17. 1. 276-276
ｍore...
Books (4)：
  • 血管・リンパ管の機能制御と疾患メカニズム
    化学同人 2022 ISBN:9784759817355
  • 心臓
    日本医学出版 2022
  • 医学のあゆみ
    2019
  • Advances in Stem Cells and their Niches
    2019
Lectures and oral presentations  (101)：
  • Investigation of the molecular pathogenesis of aortic dissection in Fibrillin-1 mutant mice by synchrotron imaging and transcriptomics analysis
    (第7回日本循環器学会 基礎研究フォーラム(BCVR))
  • Cell Lineage Analysis of CD73-Positive Cells in the Bone Marrow Microenvironment
    (第46回日本分子生物学会年会)
  • Maintaining differentiated cell identity during aging -- insights from Drosophila enteroendocrine cells
    (第46回日本分子生物学会年会)
  • A Novel Mutation in the Hybrid1 Domain of the Fibrillin 1 Gene Causes Tight Skin Phenotype
    (第7回エラスチン・関連分子研究会学術集会)
  • A Novel Mutation in the Hybrid1 Domain of the Fibrillin 1 Gene Causes an Abnormal Skin Phenotype
    (Tissue, Matrix, and Pathobiology: Joint Meeting of ASMB, HCS, and ASIP)
ｍore...
Education (2)：
  • 1988 - 1993 Graduate School of University of Tsukuba
  • 1980 - 1986 University of Tsukuba School of Medicine
Professional career (2)：
  • 博士(医学) (筑波大学)
  • Ph.D. (University of Tsukuba)
Work history (9)：
  • 2015/09 - 現在 University of Tsukuba TARA Center Professor
  • 2020/04 - 2022/03 筑波大学学長補佐
  • 2014/09 - 2015/08 University of Tsukuba TARA Center Professor
  • 2011/09 - 2015/08 University of Texas Southwestern Medical Center at Dallas Department of Molecular Biology Associate Professor (Tenured)
  • 2003/09 - 2011/08 University of Texas Southwestern Medical Center at Dallas Department of Molecular Biology Assistant Professor
Show all
Committee career (18)：
  • 2022/01 - 現在 International Society for Matrix Biology Council member
  • 2022/01 - 現在 Matrix Biology and Matrix Biology Plus Editor
  • 2021/12 - 現在 Vascular Pharmacology Editorial Board Member
  • 2021/09 - 現在 Frontiers in Cardiovascular Medicine Associate Editor (Atherosclerosis and Vascular Medicine)
  • 2021/04 - 現在 Frontiers in Cell and Developmental Biology Guest Editor (Extracellular Matrix Dynamics in Biology, Bioengineering and Pathology -Volume II)
Show all
Awards (5)：
  • 2016 - Mizutani Foundation for Glycoscience
  • 2015 - 上原記念生命科学財団研究助成
  • 2015 - 内藤記念科学財団研究助成
  • 2012 - American Heart Association Established Investigator Award (AHA)
  • 2008 - American Society for Matrix Biology Junior Investigator Award (ASMB)
Association Membership(s) (15)：
European Society of Cardiology ,  International Society for Matrix Biology ,  THE JAPANESE SOCIETY FOR CARDIOVASCULAR SURGERY ,  The Japanese Biochemical Society ,  The Molecular Biology Society of Japan ,  日本循環器学会 ,  Japan Elastin Meeting ,  Jananese Society for Matirx Biology and Medicine ,  日本血管生物医学会 ,  日本心血管内分泌代謝学会 ,  North American Vascular Biology Organization ,  American Heart Association (AHA), 2017- FAHA ,  American Society for Matrix Biology ,  JAPAN PEDIATRIC SOCIETY ,  老化促進モデルマウス(SAM)学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM