SATO Michio

Affiliation and department：

Research field (1)： Bioorganic chemistry

Research theme for competitive and other funds (7)：

2024 - 2027 Natural Products Biology: Physiological significance of plant secondary metabolites
2022 - 2026 Understanding a mechanism of an onset of colorectal cancer by colibactin and finding a inhibitor to the biosynthetic enzymes
2022 - 2025 Identification of target molecules based on self-resistance gene-directed genome mining
2019 - 2022 Integrating Computational and Experimental Approaches for New Paradigms in Molecule Synthesis
2019 - 2022 Compound discovery by target mining using potential target molecules

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Papers (50)：

Sato M, Sakano S, Nakahara M, Tamura Y, Hara K, Hashimoto H, Tang Y, Watanabe K. Uncommon arrangement of self-resistance allows biosynthesis of de novo purine biosynthesis inhibitor that acts as an immunosuppressor. Journal of the American Chemical Society. 2023. 145. 49. 26883-26889
Chiharu Iwasaka, Yuka Ninomiya, Takashi Nakagata, Hinako Nanri, Daiki Watanabe, Harumi Ohno, Kumpei Tanisawa, Kana Konishi, Haruka Murakami, Yuta Tsunematsu, et al. Association between physical activity and the prevalence of tumorigenic bacteria in the gut microbiota of Japanese adults: a cross-sectional study. Scientific reports. 2023. 13. 1. 20841-20841
Kanji Niwa, Masao Ohashi, Kaili Xie, Chen-Yu Chiang, Cooper S. Jamieson, Michio Sato, Kenji Watanabe, Fang Liu, K. N. Houk, Yi Tang. Biosynthesis of Polycyclic Natural Products from Conjugated Polyenes via Tandem Isomerization and Pericyclic Reactions. Journal of the American Chemical Society. 2023
Mai Kato, Momoka Yamaguchi, Akira Ooka, Ryota Takahashi, Takuji Suzuki, Keita Onoda, Yuko Yoshikawa, Yuta Tsunematsu, Michio Sato, Yasukiyo Yoshioka, et al. Non-target GC-MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice. Scientific reports. 2023. 13. 1. 8924-8924
Keita Onoda, Mai Kato, Yuta Tsunematsu, Fumihiro Eto, Michio Sato, Yasukiyo Yoshioka, Takuya Yoshida, Kentaro Tamura, Ikuko Yao, Hideo Dohra, et al. Biosynthetic Gene Expression and Tissue Distribution of Diosgenin in Dioscorea japonica. Journal of agricultural and food chemistry. 2023. 71. 10. 4292-4297

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MISC (24)：

佐藤道大, 渡辺賢二. ゲノム情報に基づく新規生合成システムのリデザイン. 月刊ファインケミカル. 2021. 50. 4. 40-46
佐藤道大, 渡辺賢二. ディールス-アルダラーゼとはどういった酵素なのか?. 月刊化学. 2021. 76. 72-72
岩崎基, 金原里恵子, 山地太樹, 片桐諒子, 武藤倫弘, 恒松雄太, 佐藤道大, 渡辺賢二, 細見晃司, 國澤純, et al. コリバクチン産生大腸菌の有無と大腸腫瘍との関連. がん予防学術大会プログラム・抄録集. 2021. 2021 (CD-ROM)
岸本真治, 佐藤道大, JAMIESON Cooper, 横山葵, 成田一仁, 前田直哉, 恒松雄太, 原幸大, 橋本博, HOUK Kendall. N., et al. Mechanism of CghA, Diels-Alderase from Chaetomium globosum. 日本農芸化学会大会講演要旨集(Web). 2020. 2020
佐藤道大, 岸本真治, JAMIESON Cooper S., 原幸大, 橋本博, 恒松雄太, KENDALL Houk N., KENDALL Houk N., TANG Yi, TANG Yi, et al. Diastereoselectivity and product inhibition evasion by Diels-Alderase. 天然有機化合物討論会講演要旨集(Web). 2020. 62nd

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Education (2)：

2006 - 2011 Hokkaido University Graduate School of Agriculture Research Faculty of Agriculture
2002 - 2006 Hokkaido University Faculty of Agriculture Department of Bioscience and Chemistry

Work history (7)：

2023/04 - 現在 University of Shizuoka School of Pharmaceutical Sciences
2017/11 - 2023/03 University of Shizuoka School of Pharmaceutical Sciences
2017/04 - 2017/10 University of Shizuoka School of Pharmaceutical Sciences
2015/08 - 2017/03 University of California, Los Angeles
2014/08 - 2015/07 UC Berkeley Department of Chemical and Biomolecular Engineering Postdoctoral fellow

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Awards (2)：

2021/03 - 2021年度農芸化学奨励賞
2016/10 - 平成28年度日本薬学会生薬・天然物部会奨励研究賞

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