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J-GLOBAL ID：201801020569292939   Update date: Dec. 24, 2024

Shirota Hidekazu

シロタ ヒデカズ | Shirota Hidekazu
Affiliation and department：
Tohoku University

About Tohoku University


Research field  (1)： Immunology
Research keywords  (1)： Tumor immunology
Research theme for competitive and other funds  (5)：
  • 2022 - 2025 生体内の腫瘍細胞死が及ぼす腫瘍微小環境の変化
  • 2019 - 2022 The role of humoral immunity in tumor microenvironment
  • 2016 - 2018 IL-4をターゲットとした癌免疫療法の開発
  • 2014 - 2017 Development of a novel anti-cancer immune therapy using the synthetic oligonucleotide containing poly-G motif
  • 2013 - 2015 腫瘍環境における慢性炎症・免疫細胞の機能解析と癌治療への応用
Papers (95)：
  • Yuki Kasahara, Ken Saijo, Reio Ueta, Ryunosuke Numakura, Keiju Sasaki, Yuya Yoshida, Sakura Taniguchi, Kota Ouchi, Keigo Komine, Hiroo Imai, et al. Pretreatment neutrophil-lymphocyte ratio as a prognostic factor in recurrent/metastatic head and neck cancer treated with pembrolizumab. Scientific reports. 2024. 14. 1. 28255-28255
  • Yuya Yoshida, Masanobu Takahashi, Keigo Komine, Sakura Taniguchi, Hideharu Yamada, Keiju Sasaki, Sho Umegaki, Yoshifumi Kawamura, Yuki Kasahara, Kota Ouchi, et al. Correlation between Efficacy and Cardiovascular Adverse Events in Patients with Advanced Solid Cancer Who Received VEGF Pathway Inhibitors: Hypertension within the First Eight Weeks is Associated with Favorable Outcomes of Patients Treated with VEGF Pathway Inhibitors. Internal medicine (Tokyo, Japan). 2024
  • Kota Ouchi, Shin Takahashi, Keiju Sasaki, Yuya Yoshida, Sakura Taniguchi, Yuki Kasahara, Keigo Komine, Hiroo Imai, Ken Saijo, Hidekazu Shirota, et al. Genome-wide DNA methylation status is a predictor of the efficacy of anti-EGFR antibodies in the second-line treatment of metastatic colorectal cancer: Translational research of the EPIC trial. International journal of colorectal disease. 2024. 39. 1. 89-89
  • Hiroo Imai, Ken Saijo, Noriko Takenaga, Keigo Komine, Kota Ouchi, Yuki Kasahara, Shiori Ishikawa, Keiju Sasaki, Yuya Yoshida, Hidekazu Shirota, et al. Chylous Ascites Associated with Advanced Pancreatic Cancer That Improved with Appropriate Treatment: A Case Report. Current oncology (Toronto, Ont.). 2024. 31. 3. 1477-1482
  • Sakura Hiraide Taniguchi, Keigo Komine, Noriko Takenaga, Yuya Yoshida, Keiju Sasaki, Yoshifumi Kawamura, Yuki Kasahara, Kota Ouchi, Hiroo Imai, Ken Saijo, et al. FOLFIRI Chemotherapy for Patients With Metastatic Urachal Carcinoma. Anticancer research. 2023. 43. 12. 5699-5704
ｍore...
MISC (56)：
  • 岩崎智行, 菱沼英史, 菱沼英史, 城田英和, 城田英和, 笠原佑記, 笠原佑記, 梅垣翔, 佐々木啓寿, 佐々木啓寿, et al. Characterization of plasma metabolomics and proteomics profiling in patients with CRP-positive squamous cell carcinoma. 日本臨床腫瘍学会学術集会(CD-ROM). 2024. 21st
  • 小峰啓吾, 高橋雅信, 高橋雅信, 岩崎智行, 岩崎智行, 大内康太, 吉田裕也, 吉田裕也, 沼倉龍之助, 沼倉龍之助, et al. Efficacy and safety of DOAC for treatments of VTE in patients undergoing cancer drug treatment. 日本臨床腫瘍学会学術集会(CD-ROM). 2023. 20th
  • 岩崎智行, 菱沼英史, 菱沼英史, 城田英和, 城田英和, 笠原佑記, 笠原佑記, 梅垣翔, 梅垣翔, 佐々木啓寿, et al. Characterization of plasma metabolomics and proteomics profiling in patients with CRP-positive squamous cell carcinoma. 日本癌学会学術総会抄録集(Web). 2023. 82nd
  • 山本貴也, 城田英和, 井上千裕, 松下晴雄, 梅澤玲, 石川陽二郎, 石岡千加史, 神宮啓一. Chemoradiotherapy for metastatic primary cardiac angiosarcoma. 臨床放射線. 2019. 64. 11. 1369-1374
  • Keigo Komine, Masanobu Takahashi, Sakura Hiraide, Hideharu Yamada, Mari Tsubata, Masahiro Takahashi, Shin Takahashi, Hidekazu Shirota, Tetsuya Niihori, Yoko Aoki, et al. Adoption of multigene panel testing for hereditary cancer "CancerNext" in Tohoku University Hospital. ANNALS OF ONCOLOGY. 2019. 30
ｍore...
Patents (1)：
  • Compositions and Methods for the Treatment of Cancer
Books (4)：
  • Immunopotentiators in Modern Vaccines Second Edition
    Science & Technology Books, Life Science Academic Press/Elsevier. 2018
  • Inflammation / From Molecular and Cellular Mechanisms to the Clinic"
    Wiley-VCH Verlag GmbH & Co. KGaA, 2017
  • Nucleic Acids in Innate Immunity
    CRC Press 2008
  • Vaccine Adjuvants and Delivery Systems
    Manmohan Singh. 2006
Lectures and oral presentations  (1)：
  • 東北大学における未来型医療創生とがんゲノム医療への取り組み
    (第16回日本臨床腫瘍学会学術集会 2018)
Education (2)：
  • 1998 - 2002 東北大学大学院 医学系研究科 医科学博士課程
  • 1990 - 1996 Fukushima Medical University School of Medicine
Professional career (1)：
  • Ph. D. (Tohoku University)
Work history (5)：
  • 2017/08 - 現在 東北大学医学系研究科 地域がん医療推進センター 准教授
  • 2012/06 - 2017/07 東北大学医学系研究科 地域がん医療推進センター 講師
  • 2008/04 - 2012/05 米国国立衛生研究所 国立癌研究所 スタッフサイエンティスト
  • 2007/04 - 2008/03 東北大学医学系研究科 感染症・呼吸器内科 助教
  • 2002/04 - 2007/03 米国食品医薬品庁 生物製剤評価研究センター 博士研究員
Awards (1)：
  • 2011 - National Cancer Institute, NIH Technology Transfer Award
Association Membership(s) (6)：
JAPANESE SOCIETY OF ALLERGOLOGY ,  THE JAPANESE CANCER ASSOCIATION ,  JAPAN SOCIETY OF CLINICAL ONCOLOGY ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  JSMO ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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