Research theme for competitive and other funds (6):
2022 - 2025 Elucidate the regulation mechanism of cardiac fibrosis by the stretch stimulus
2022 - 2025 循環器疾患のサルコペニアとその対策としてのリハビリ法の開発・分子機構の解明
2019 - 2022 Effects and Molecular Mechanisms of WAON Therapy on Cognitive Function and Muscle Strength Improvement in Elderly Heart Failure Patients
2019 - 2022 Development of rehabilitation method applying physical stimulation as countermeasure for sarcopenia and elucidation of its underlying molecular mechanisms
2018 - 2021 Elucidate the regulational mechanism of de-differentiation of cardiac myofibroblast in response to stretch
2014 - 2016 The study about the effect of stretch on the differentiation of cardiac fibroblast
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Papers (41):
Gaku Oguri, Ryo Ikegami, Haruka Ugawa, Manami Katoh, Syotaro Obi, Masashi Sakuma, Norihiko Takeda, Yutaka Kano, Shigeru Toyoda, Toshiaki Nakajima. Muscle Atrophy and mRNA-miRNA Network Analysis of Vascular Endothelial Growth Factor (VEGF) in a Mouse Model of Denervation-Induced Disuse. Cureus. 2024
Takafumi Nakajima, Taira Fukuda, Ikuko Shibasaki, Syotaro Obi, Masashi Sakuma, Shichiro Abe, Hirotsugu Fukuda, Shigeru Toyoda, Toshiaki Nakajima. Pathophysiological roles of the serum acylcarnitine level and acylcarnitine/free carnitine ratio in patients with cardiovascular diseases. International Journal of Cardiology. Heart & Vasculature. 2024. 51. 101386-101386
Serum Adiponectin Levels Correlate with Atrial PPAR γ and TGF β1 mRNA Expression in Cardiac Surgery Patients: Involvement of Atrial Fibrosis. 2024. 88回. OJ04-1
Toshiaki Nakajima, Akiko Haruyama, Taira Fukuda, Kentaro Minami, Suguru Hirose, Hiroko Yazawa, Takafumi Nakajima, Takaaki Hasegawa, Yoshiyuki Kitagawa, Syotaro Obi, et al. Left atrial reservoir strain is a marker of atrial fibrotic remodeling in patients undergoing cardiovascular surgery: Analysis of gene expression. PloS one. 2024. 19. 7. e0306323
Ryoichi Sohma, Masashi Sakuma, Syotaro Obi, Setsu Nishino, Ken-Ichi Inoue, Satoko Kishimoto, Tianyang Lu, Shigeru Toyoda, Teruo Inoue. Effects of the factor Xa inhibitor rivaroxaban on the differentiation of endothelial progenitor cells. BMC cardiovascular disorders. 2023. 23. 1. 282-282