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J-GLOBAL ID:201901000114636164   Update date: Jan. 15, 2025

KUBOTA Yasushi

クボタ ヤスシ | KUBOTA Yasushi
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Research field  (7): Genomics ,  Genetics ,  Internal medicine - General ,  Hematology and oncology ,  Healthcare management, medical sociology ,  Developmental biology ,  Tumor diagnostics and therapeutics
Research keywords  (11): がんゲノム ,  臨床検査医学 ,  輸血医学 ,  臨床倫理 ,  Hematology & Oncology ,  Leukemia ,  Hematopoietic stem cell ,  Leukemia stem cell ,  環状オリゴ糖シクロデキストリン ,  フローサイトメトリー ,  オートファジー
Research theme for competitive and other funds  (11):
  • 2024 - 2027 Development of a novel therapeutic strategy for leukemia by inducing autophagy with cyclodextrins.
  • 2020 - 2023 Development of new drugs and elucidation of immunity to cure all chronic myeloid leukemia patients
  • 2020 - 2023 新規核酸医薬技術と葉酸修飾シクロデキストリンを用いる白血病治療法の開発
  • 2017 - 2020 Exploring biomarkers concerning NK immunity that favor treatment discontinuation in CML patients
  • 2016 - 2020 Development of a novel therapy targeting intracellular cholesterol for leukemia
Show all
Papers (108):
  • Toshiaki Nagaie, Yasushi Kubota, Ichiro Hanamura, Sivasundaram Karnan, Rika Tomimasu, Michiaki Akashi, Shiho Tsuruda, Akiyoshi Takami, Shinya Kimura, Masaharu Miyahara. Diffuse Large B-Cell Lymphoma with t(1;22)(q21;q11.2) and t(6;18)(p25;q21): A Case Report. Reports. 2025. 8. 1. 5-15
  • Ayano Sugihara, Yasushi Kubota, Toshiaki Nagaie, Mai Fujita, Keitaro Ishii, Sho Okamoto, Hiroshi Ureshino, Hiroo Katsuya, Mai Takeuchi, Keita Kai, et al. Epstein-Barr virus-associated lymphoproliferative disease during remission after induction therapy with dasatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: a case report. Annals of hematology. 2024
  • Yasushi Kubota, Shinya Kimura. Current Understanding of the Role of Autophagy in the Treatment of Myeloid Leukemia. International journal of molecular sciences. 2024. 25. 22
  • Yamada Marie, Yamada Naotomo, Kubota Yasushi, Takahashi Emi, Nakao Mami, Miyazaki Toru, Sato Shinichiro, Nakamura Hideaki, Kimura Shinya, Sueoka Eisaburo. A patient with partial E phenotype expressing alloanti-E antibody after transfusion with platelet concentrates(タイトル和訳中). Laboratory Medicine International. 2024. 3. 3. 66-69
  • Yasushi Kubota, Haruhiko Sano, Yuji Takeda, Kyosuke Yamaguchi, Hideaki Nakamura, Keita Kai, Keisuke Kidoguchi, Kana Kusaba, Masako Yokoo, Toshihiko Ando, et al. Pure Red Cell Aplasia in a Patient with Thymic Hyperplasia, Hypogammaglobulinemia and Adult T-cell Leukemia/Lymphoma. Internal medicine (Tokyo, Japan). 2024
more...
MISC (134):
  • 堀口 博史, 永沼 謙, 松永 洸昂, 平田 公美, 坂田 憲幸, 高橋 康之, 阿南 朋恵, 久保田 寧, 村上 千明, 山下 高久, et al. 脳実質及び脊髄に局在するPrimary central nervous system peripheral T-cell lymphomaの一例. 日本リンパ網内系学会会誌. 2024. 64. 116-116
  • 坂田 憲幸, 松永 洸昂, 平田 公美, 川田 泰輔, 永沼 謙, 高橋 康之, 阿南 朋恵, 久保田 寧, 木崎 昌弘, 山本 晃士, et al. 高齢発症の後天性血友病Aに対してエミシズマブを使用した2症例. 臨床血液. 2024. 65. 4. 307-307
  • 安田 絵理子, 鈴木 康巴, 野呂 光恵, 阿南 昌弘, 久保田 寧, 山本 晃士. 顕著な出血症状に対する止血管理が成功した後天性血友病Aの1例. 日本輸血細胞治療学会誌. 2024. 70. 2. 361-361
  • 安田 絵理子, 鈴木 康巴, 野呂 光恵, 阿南 昌弘, 久保田 寧, 山本 晃士. 顕著な出血症状に対する止血管理が成功した後天性血友病Aの1例. 日本輸血細胞治療学会誌. 2024. 70. 2. 361-361
  • 坂田 憲幸, 松永 洸昂, 平田 公美, 川田 泰輔, 永沼 謙, 高橋 康之, 阿南 朋恵, 久保田 寧, 木崎 昌弘, 山本 晃士, et al. 高齢発症の後天性血友病Aに対してエミシズマブを使用した2症例. 臨床血液. 2024. 65. 4. 307-307
more...
Books (9):
  • EBM 血液疾患の治療 2023-2024 edition
    中外医学社 2022
  • 1.総論-検査の選び方・進め方 1.血液一般検査 c)凝固・線溶異常(凝固異常症の鑑別,凝固亢進型と線溶亢進型の評価と意義)
    2015
  • 1.総論-検査の選び方・進め方 1.血液一般検査 c)凝固・線溶異常(凝固異常症の鑑別,凝固亢進型と線溶亢進型の評価と意義)
    2015
  • Regulators of the Proliferation of Hematopoietic Stem and Progenitor Cells During Hematopoietic Regeneration.
    InTech 2013
  • Regulators of the Proliferation of Hematopoietic Stem and Progenitor Cells During Hematopoietic Regeneration.
    InTech 2013
more...
Lectures and oral presentations  (93):
  • 白血病細胞をオートファジー細胞死に導く葉酸修飾シクロデキストリンの開発
    (第28回 日本がん分子標的治療学会学術集会 2024)
  • An unusual progression of DLBCL accompanied by abundant T cell infiltrations and composite of AITL.
    (第83回日本血液学会学術集会.(完全Web開催) 2021)
  • Two distinct presentation mode of PRCA with thymic hyperplasia, hypogammaglobulinemia and ATL.
    (第83回日本血液学会学術集会.(完全Web開催) 2021)
  • First, second, and third attempts at TKI discontinuation in patients with CML.
    (第83回日本血液学会学術集会.(完全Web開催) 2021)
  • The clinical importance of DNMT3A, NPM1, and FLT3-ITD triple-mutation in Japanese AML.
    (第83回日本血液学会学術集会.(完全Web開催) 2021)
more...
Education (2):
  • 2003 - 2007 Kyoto University Graduate School of Medicine
  • 1991 - 1997 Saga Medical School Faculty of Medicine
Professional career (1):
  • 医学博士 (京都大学)
Work history (5):
  • 2024/04 - 現在 Saga-Ken Medical Centre KOSEIKAN Department of Clinical Laboratory Medicine Department Head
  • 2021/07 - 2024/03 Saitama Medical University, Saitama Medical Center Department of Transfusion Medicine and Cell Therapy Professor
  • 2012/10 - 2021/06 Saga University, Faculty of Medicine Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine Lecturer
  • 2010/04 - 2012/09 Saga University, Faculty of Medicine Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine Assistant professor
  • 2007/04 - 2010/03 RIKEN Center for Developmental Biology Laboratory for Stem Cell Biology Research Associate
Committee career (8):
  • 2025/01 - 現在 Japanese Society of Laboratory Medicine Councilor
  • 2024/12 - 現在 一般社団法人日本輸血・細胞治療学会 九州支部 評議員
  • 2024/11 - 現在 九州遺伝子診断研究会 世話人
  • 2024/03 - 現在 Japanese Society for Transplantation and Cell Therapy Councilor
  • 2022/09 - 現在 Japanese Society of Hematology COI committee
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Awards (3):
  • 2016/11 - 日本白血病研究基金 一般研究賞
  • 2010/06 - European Hematology Association 15th EHA Congress Travel Award Identification of long-term hematopoietic stem cell without negative selection
  • 2007/10 - Japanese Society of Hematology 69th JSH congress Best Poster Award
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