Rchr
J-GLOBAL ID：201901000185929227   Update date: May. 28, 2024

Ohara Hiroki

Ohara Hiroki
Affiliation and department：
Shimane University

About Shimane University


Research field  (1)： Laboratory animal science
Research theme for competitive and other funds  (7)：
  • 2023 - 2026 ダブルコンジェニックSHRSP/Izmを用いた河内晩柑果皮の脳血管障害防御機構の解析
  • 2023 - 2026 Exploration of immunogenetic and molecular basis of hypertensive disease aiming at establishment of novel preventive and therapeutic strategies
  • 2017 - 2020 Dysfunction of STIM1 and Hypertesnion: evaluation using a novel genome-edited SHRSP
  • 2015 - 2018 Is the Blood-Brain Barrier Weakened in Genetic Stroke Model Rats? A Study Utilizing in vitro Models System
  • 2014 - 2016 Identification of stroke susceptible genes in the stroke-spontaneously hypertensive rats and evaluation of its molecular pathogenesis
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Papers (31)：
  • Hiroki Ohara, Fumihiko Takeuchi, Norihiro Kato, Toru Nabika. Genotypes of Stim1 and the proximal region on chromosome 1 exert opposite effects on stroke susceptibility in stroke-prone spontaneously hypertensive rat. Journal of hypertension. 2023
  • Hiroyuki Matsuo, Kohei Kawakami, Hiroki Ohara, Takehito Kaneko, Tomoji Mashimo, Takaya Yamada, Toru Nabika. Apolipoprotein E-depletion accelerates arterial fat deposition in the spontaneously hypertensive rat. Experimental animals. 2023
  • Hiroki Ohara, Toru Nabika. Genetic Modifications to Alter Blood Pressure Level. Biomedicines. 2022. 10. 8
  • Zinat Mahal, Hiroyuki Matsuo, Hasan M Zahid, Yoshitomo Notsu, Hiroki Ohara, Kenji Okamoto, Toru Nabika. Milk Fermented with Mushrooms Prevents Stroke in the Stroke-Prone Spontaneously Hypertensive Rats Independently of Blood Pressure. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2022. 31. 5. 106421-106421
  • Mei Wang, Hiroki Ohara, Masahiro Egawa, Shohei Fukunaga, Hiroyuki Matsuo, Zhi-Ru Ge, Toru Nabika. A 3-Mbp fragment on rat chromosome 1 affects susceptibility both to stroke and kidney injury under salt loading in the stroke-prone spontaneously hypertensive rat: a genetic approach using multiple congenic strains. Experimental animals. 2022
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MISC (15)：
  • Hiroyuki Matsuo, Takehito Kaneko, Koichi Fujikawa, Hiroki Ohara, Tomoji Mashimo, Toru Nabika. DEVELOPMENT OF A NEW MODEL FOR COMBINED ATHEROSCLEROSIS AND HYPERTENSION: APOE-KNOCKOUT SPONTANEOUSLY HYPERTENSIVE RAT. ATHEROSCLEROSIS. 2017. 263. E86-E86
  • Xiao Bing, Liu Fan, Ohara Hiroki, Nabika Toru. Identification of Stim1 as a Candidate Gene for Exaggerated Sympathetic Response to Stress in the Stroke-Prone Spontaneously Hypertensive Rat. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2014. 64. 16. C76-C76
  • 岡崎 泰昌, 胡 茜, 赤塚 慎也, 山下 享子, 舟橋 諭美, 山下 依子, 蒋 麗, 大原 浩貴, 周 珊瑚, 永井 裕崇, et al. 鉄化合物による高悪性度肉腫型中皮腫の表現型に関与するmicroRNAの検出と機能解析(Detection and functional analyses of microRNA in high-grade phenotype of iron-induced sarcomatoid mesothelioma in rats). 日本癌学会総会記事. 2011. 70回. 266-267
  • 岡崎 泰昌, 胡 茜, 赤塚 慎也, 山下 依子, 大原 浩貴, 蒋 麗, 永井 裕崇, 高橋 隆, 豊國 伸哉. CDKN2A/2Bのホモ欠損は鉄誘発高悪性度ラット中皮腫の特徴である(Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced hieh-grade rat mesothelioma). 日本癌学会総会記事. 2010. 69回. 218-218
  • 岡崎 泰昌, 胡 茜, 赤塚 慎也, 山下 依子, 大原 浩貴, 永井 裕崇, 高橋 隆, 豊國 伸哉. CDKN2A/2Bのホモ欠損は鉄誘発高悪性度ラット中皮腫の特徴である. 日本病理学会会誌. 2010. 99. 1. 298-298
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