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J-GLOBAL ID：201901002330217330 Update date: Feb. 26, 2025

Ishizaki Toshimasa

イシザキトシマサ | Ishizaki Toshimasa

Affiliation and department：

Research field (1)： Pharmacology

Research theme for competitive and other funds (22)：

2021 - 2026 Development of innovative AI methods for predicting therapeutic targets for intractable diseases from medical big data
2022 - 2025 皮膚恒常性維持シグナルを標的とした慢性炎症性皮膚疾患治療基盤構築
2020 - 2023 molecular design and action mechanism of peptidomimetics using natural products-like cubic scaffolds
2020 - 2023 Development and validation of novel methods for designing small molecule peptidomimetics
2019 - 2022 Investigation of skin homeostasis based on the regulation of actin cytoskeleton

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Papers (96)：

Takeshi Terabayashi, Takako Sasaki, Toshimasa Ishizaki, Tadashi Tomo, Yoshihiro Nishida, Katsuhiro Hanada. Analysis of accumulation of DNA double-strand breaks in mouse tissues by pulsed-field gel electrophoresis. Toxicology and Applied Pharmacology. 2025. 497. 117278-117278
Takeshi Terabayashi, Daisuke Takezaki, Katsuhiro Hanada, Shigeru Matsuoka, Takako Sasaki, Takahiro Akamine, Akira Katoh, Toshimasa Ishizaki. Timosaponin AIII Disrupts Cell-Extracellular Matrix Interactions through the Inhibition of Endocytic Pathways. Biological and Pharmaceutical Bulletin. 2024. 47. 10. 1648-1656
Takahiro Akamine, Takeshi Terabayashi, Takako Sasaki, Riku Hayashi, Ichitaro Abe, Fumihiro Hirayama, Shin-ichi Nureki, Masahito Ikawa, Haruhiko Miyata, Akinori Tokunaga, et al. Conditional deficiency of Rho-associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice. FEBS Open Bio. 2024
Kazuhiro Sumida, Tomomitsu Doi, Kunie Obayashi, Yosuke Chiba, Shohei Nagasaka, Noriyoshi Ogino, Koichiro Miyagawa, Ryoko Baba, Hiroyuki Morimoto, Hideki Hara, et al. Caspase-4 has a role in cell division in epithelial cells through actin depolymerization. Biochemical and Biophysical Research Communications. 2023. 149394-149394
Masahiro Nishida, Takeshi Terabayashi, Shigeru Matsuoka, Tomoko Okuma, Sawako Adachi, Tadashi Tomo, Masanori Kawano, Kazuhiro Tanaka, Hiroshi Tsumura, Hirofumi Anai, et al. Mechanism of action of non-camptothecin inhibitor Genz-644282 in topoisomerase I inhibition. Communications Biology. 2022. 5. 1

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MISC (96)：

西澤俊哉, 寺林健, 佐々木隆子, 山西芳裕, 石崎敏理. 神経伝達物質シグナルはシスプラチン誘発急性腎障害に対して保護効果を示す. 日本腎臓学会誌. 2024. 66. 4. 611-611
寺林健, 小迫英尊, 花田克浩, 佐々木隆子, 赤嶺孝祐, 石崎敏理. アクチン細胞骨格の生物学・疾患における多面性と普遍性皮膚恒常性維持に果たすROCKを介したアクチン再編成の役割. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [1S08e-05]
赤嶺孝祐, 寺林健, 佐々木隆子, 石崎敏理. ROCKシグナリングから迫る新規肺血管透過性制御機構の解明. 日本薬学会年会要旨集. 2022. 142年会. 28N-pm18
上大介, 石崎敏理, 加藤明良, 小路弘行, 五條理志. RNA分解をターゲットにした新規化合物の探索と脂肪分化誘導抑制. 生体機能と創薬シンポジウム要旨集. 2021. 2021
土井知光, 土井知光, 土井知光, 北條宏徳, 大庭伸介, 大庭伸介, 大林邦衣, 遠藤元誉, 石崎敏理, 加藤明良, et al. Activator protein-1 coordinates coactivator CREB-binding protein and p300 usage for β-catenin. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th

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