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J-GLOBAL ID：201901002502176968 Update date: Mar. 13, 2025

Hashimoto Michihiro

ハシモトミチヒロ | Hashimoto Michihiro

Affiliation and department：

Research field (4)： Laboratory animal science , Cell biology , Molecular biology , Pathobiochemistry

Research keywords (7)：がん , 加齢性疾患 , Acidic phospholipid , Lifestyle disease , Brown adipocyte , Aging , Cellular senescence

Research theme for competitive and other funds (14)：

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Papers (18)：

Michihiro Hashimoto, Ayumi Goto, Shanlou Qiao, Hitoshi Yamashita. Aged mice overexpressing cellular repressor of E1A-stimulated genes 1 in adipose tissues exhibited increased liposarcoma incidence and shortened lifespan. Biochemical and Biophysical Research Communications. 2025. 753. 151454-151454
Takayuki Kawaguchi, Michihiro Hashimoto, Reiko Nakagawa, Ryunosuke Minami, Masahito Ikawa, Jun-ichi Nakayama, Jun Ueda. Comprehensive posttranslational modifications in the testis-specific histone variant H3t protein validated in tagged knock-in mice. Scientific Reports. 2024. 14. 1. 21305
Yuki Endo, Michihiro Hashimoto, Tatsuya Kusudo, Tadashi Okada, Tamaki Takeuchi, Ayumi Goto, Hitoshi Yamashita. CREG1 improves diet-induced obesity via uncoupling protein 1-dependent manner in mice. Genes to Cells. 2022. 27. 3. 202-213
Koichiro Kawaguchi, Michihiro Hashimoto, Ryuta Mikawa, Azusa Asai, Tadashi Sato, Masataka Sugimoto. Protocol for assessing senescence-associated lung pathologies in mice. STAR Protocols. 2021. 2. 4. 100993-100993
Tatsuya Kusudo, Tadashi Okada, Michihiro Hashimoto, Tamaki Takeuchi, Yuki Endo, Ayumi Niwa, Hitoshi Yamashita. CREG1 administration stimulates BAT thermogenesis and improves diet-induced obesity in mice. The Journal of Biochemistry. 2021. 171. 1. 63-73

MISC (24)：

Aging research using aP2-CREG1-Tg mice. 2020. 4. 12. 54-60
Michihiro Hashimoto, Jun Ueda, Hitoshi Yamashita. Aging research using aP2-CREG1-Tg mice. The CELL. 2020. 52. 11. 41-45
橋本理尋, 楠堂達也, 竹内環, 遠藤優貴, 山下均. 脂肪組織特異的CREG1トランスジェニックマウスを利用した褐色脂肪化促進と生活習慣病改善の検討. 基礎老化研究. 2016. 40(3). 33-35
Takahiro Seki, Ryota Mineshima, Michihiro Hashimoto, Satoshi Matsuoka, Kouji Matsumoto, Hiroshi Hara. The role of glucolipids in the regulation of ECF sigma factors in Bacillus subtilis. GENES & GENETIC SYSTEMS. 2014. 89. 6. 330-330
関貴洋, 峯島良太, 橋本理尋, 松岡聡, 松本幸次, 原弘志. 枯草菌ECFシグマ因子の活性制御における糖脂質の役割. 日本遺伝学会大会プログラム・予稿集. 2014. 86th

Lectures and oral presentations (43)：

Effects of CREG1 on voluntary exercise and pathology in a mouse model of diabetes mellitus
(2025)
CREG1が糖尿病モデルマウスの自発運動と病態に及ぼす作用の検討
(第78回日本体力医学会大会 2025)
CREG1 enhances glucose uptake via AMPK in C2C12 myotube
(第45回日本基礎老化学会大会 2022)
UCP1 is essential for the anti-obesity effect of CREG1
(2021)
CREG1 enhances muscle function in mice
(第44回日本基礎老化学会大会 2021)

Education (3)：

Professional career (1)：

Work history (8)：

2022/04 - 現在 Asahikawa Medical University School of Medicine, Medical Course
2020/12 - 2022/04 Asahikawa Medical University School of Medicine, Medical Course
2020/09 - 2020/12 旭川医科大学医学部医学科病理学講座腫瘍病理分野助教
2019/06 - 2020/09 Asahikawa Medical University
2015/04 - 2019/05 Chubu University College of Life and Health Sciences

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Committee career (4)：

Awards (5)：

Association Membership(s) (4)：

日本実験動物学会 , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE GENETICS SOCIETY OF JAPAN , JAPAN SOCIETY FOR BIOMEDICAL GERONTOLOGY

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