Rchr
J-GLOBAL ID：201901003715453562   Update date: May. 21, 2024

ISHIHARA Mikiya

イシハラ ミキヤ | ISHIHARA Mikiya
Affiliation and department：
Osaka International Cancer Institute Medical Oncology

About Osaka International Cancer Institute Medical Oncology


Job title： Vice Director
Research field  (1)： Tumor diagnostics and therapeutics
Research keywords  (2)： 腫瘍免疫 ,  腫瘍内科学
Research theme for competitive and other funds  (4)：
  • 2023 - 2026 Aim to eliminate a bottleneck in the practical realization of anticancer immunotherapy with gene-modified allogeneic gammadelta T cells.
  • 2023 - 2026 幹細胞様メモリーT細胞分画に優れるγδ-T細胞の誘導法の検討
  • 2020 - 2023 エネルギー代謝に注目した多機能遺伝子改変γδT細胞の追求
  • 2021 - 2023 MAGE-A4抗原を発現する切除不能進行・再発腫瘍に対するCAR-T細胞療法の医師主導第I相治験
Papers (29)：
  • Mikiya Ishihara, Yoshihiro Nishida, Shigehisa Kitano, Akira Kawai, Naozumi Harada, Yoshihiro Miyahara, Hiroyoshi Hattori, Kohichi Takada, Makoto Emori, Shigeki Kakunaga, et al. O16-2 Phase I trial of NY-ESO-1 TCR-T cell therapy combined with nanoparticulate vaccine but without lymphodepletion for STS. Annals of Oncology. 2023. 34. S1391-S1391
  • Akira Tsunoda, Koshi Sukeno, Hiroki Oka, Yasutaka Tono, Mikiya Ishihara, Kanako Saito, Satoshi Tamaru, Yoshiki Yamashita, Toshiro Mizuno, Isao Tawara. P40-3 Retrospective analysis of amrubicin therapy for advanced or recurrent neuroendocrine carcinoma in our facility. Annals of Oncology. 2023. 34. S1456-S1456
  • Yasutaka Tono, Koushi Sukeno, Akira Tsunoda, Hiroki Oka, Mikiya Ishihara, Kanako Saito, Satoshi Tamaru, Yoshiki Yamashita, Takumi Fujiwara, Takahito Kitajima, et al. MO36-3 Clinical management of cancer of unknown primary with unfavorable subset: A retrospective analysis. Annals of Oncology. 2023. 34. S1419-S1419
  • Mitsuo Terada, Aki Ito, Yuichiro Kikawa, Kei Koizumi, Yoichi Naito, Tatsunori Shimoi, Mikiya Ishihara, Takashi Yamanaka, Yukinori Ozaki, Fumikata Hara, et al. The Japanese Breast Cancer Society Clinical Practice Guidelines for systemic treatment of breast cancer, 2022 edition. Breast cancer (Tokyo, Japan). 2023. 30. 6. 872-884
  • Manabu Futamura, Takahiro Nakayama, Tetsuhiro Yoshinami, Chiya Oshiro, Mikiya Ishihara, Midori Morita, Akira Watanabe, Azusa Tanigichi, Masami Tsukabe, Masafumi Shimoda, et al. Detection of high-risk patients resistant to CDK4/6 inhibitors with hormone receptor-positive HER2-negative advanced and metastatic breast cancer in Japan (KBCSG-TR-1316). Breast cancer (Tokyo, Japan). 2023. 30. 6. 943-951
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MISC (32)：
  • 角田瑛, 祐野航志, 岡弘毅, 北嶋貴仁, 戸野泰孝, 石原幹也, 横江毅, 斎藤佳菜子, 田丸智巳, 山下芳樹, et al. A Retrospective Analysis of the Treatment of Esophagogastric Junction Adenocarcinoma in Our Facility. 日本臨床腫瘍学会学術集会(CD-ROM). 2022. 19th
  • Toshiaki Kobayashi, Hiroyasu Oda, Koushi Sukeno, Akira Tsunoda, Yasutaka Tono, Mikiya Ishihara, Kanako Saito, Yoshiki Yamashita, Toshiro Mizuno. Retrospective analysis of the efficacy and safety of nivolumab in patients with treatment-refractory esophageal cancer. ANNALS OF ONCOLOGY. 2021. 32. S328-S328
  • Koshi Sukeno, Akira Tsunoda, Yasutaka Tono, Hiroyasu Oda, Mikiya Ishihara, Kanako Saito, Satoshi Tamaru, Yoshiki Yamashita, Toshiro Mizuno. Retrospective analysis of the efficacy and safety of FOLFOX in patients with esophageal cancer. ANNALS OF ONCOLOGY. 2021. 32. S329-S329
  • 影山 愼一, 宮原 慶裕, 石原 幹也, 北野 滋久, 山本 昇, 加藤 栄史, 三嶋 秀行, 服部 浩佳, 舩越 建, 小島 隆嗣, et al. NY-ESO-1/TCR-T細胞輸注後のサイトカイン放出症候群と輸注細胞の特性解析. 日本がん免疫学会総会プログラム・抄録集. 2020. 24回. 159-159
  • 戸野泰孝, 斎藤佳菜子, 角田瑛, 小田裕靖, 石原幹也, 山下芳樹, 水野聡朗. 低血糖発作の制御に難渋した孤立性線維性腫瘍の一例. 日本臨床腫瘍学会学術集会(CD-ROM). 2019. 17th
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Books (1)：
  • EBM がん化学療法・分子標的治療 2011-2012
    中外医学社 2010
Lectures and oral presentations  (32)：
  • Energy metabolism spread to non-glycolysis in -TCR transduced -T cells
    (2022)
  • NY-ESO-1特異的αβTCR遺伝子導入γδT細胞のエネルギー代謝
    (第26回 日本がん免疫学会総会 2022)
  • Function and metabolism of NY-ESO-1-specific  TCR transduced Vδ2+ cells.
    (2021)
  • A novel affinity-enhanced NY-ESO-1-targeting TCR-redirected T cell transfer exhibited early-onset cytokine release syndrome and subsequent tumor responses in synovial sarcoma patients
    (ESMO 2019 2019)
  • PCR法によるMAGE-A4、NY-ESO-1およびSAGE抗原の腫瘍組織における発現(MAGE-A4, NY-ESO-1 and SAGE expression in tumor samples assessed by RT-PCR)
    (日本癌学会総会記事 2019)
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Professional career (1)：
  • 医学博士 (三重大学)
Awards (1)：
  • 2009/12 - The 32nd Annual San Antonio Breast Cancer Symposium The Avon Foundation-AACR International Scholar
Association Membership(s) (9)：
欧州臨床腫瘍学会 ,  日本輸血・細胞治療学会 ,  日本がん免疫学会 ,  日本サルコーマ治療研究学会 ,  American Society of Clinical Oncology ,  THE JAPANESE CANCER ASSOCIATION ,  日本乳癌学会 ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE ,  日本臨床腫瘍学会
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