Research field (4)：
Cell biology
, Molecular biology
, Tumor biology
, Pharmaceuticals - health and biochemistry
Research theme for competitive and other funds (13)：
2021 - 2024 膵管がんにおける一次繊毛消失の分子機構と影響の解明
2018 - 2021 Molecular mechanism and impact of loss of primary cilia in PDAC cells
2015 - 2018 Molecular mechanism of ciliary vesicle formation in mammalian cells
2015 - 2017 一次繊毛局在性GPCRのシグナル制御と輸送メカニズムの解明
2014 - 2016 膵管癌細胞における一次繊毛消失機構の解明と癌治療への応用
2013 - 2016 Analysis of the regulatory mechanisms of G protein-coupled receptor signaling
2013 - 2015 Regulation of primary cilia formation cycle by Kif24
2008 - 2010 Regulation of intracellular vesicle transport by small GTPase cycles
2008 - 2009 遺伝学的手法による上皮細胞の蛋白質選別輸送の解析
2005 - 2009 Functional analysis of atypical G proteins involved in cell signaling network
2007 - 2008 Comprehensive analysis of genes involved in the regulation of subcellular localization of drug transporters
2006 - 2007 Membrane-Transport Signaling Involving the GTPase Cycle of G proteins
2006 - 2007 細胞の増殖と分裂に介在する新奇低分子量G蛋白質群の機能解析
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Papers (28)：
Toshihiko Fushimi, Tetsuo Kobayashi, Hiroshi Itoh. CEP164-GLI2 association ensures the hedgehog signaling in pancreatic cancer cells. Biochemical and Biophysical Research Communications. 2023. 666. 179-185
Yu Mashima, Hayato Nohira, Hiroki Sugihara, Brian David Dynlacht, Tetsuo Kobayashi, Hiroshi Itoh. KIF24 depletion induces clustering of supernumerary centrosomes in PDAC cells. Life Science Alliance. 2022. 5. 11. e202201470-e202201470
Tetsuo Kobayashi, Tatsuya Ikeda, Reo Ota, Takafumi Yasukawa, Hiroshi Itoh. Atypical small GTPase RABL3 interacts with RAB11 to regulate early ciliogenesis in human cells. Journal of Cell Science. 2022
Pablo Barbeito, Yuki Tachibana, Raquel Martin-Morales, Paula Moreno, Kirk Mykytyn, Tetsuo Kobayashi, Francesc R Garcia-Gonzalo. HTR6 and SSTR3 ciliary targeting relies on both IC3 loops and C-terminal tails. Life Science Alliance. 2021. 4. 3. e202000746-e202000746
