Rchr
J-GLOBAL ID:201901006102204186
Update date: Oct. 20, 2024 Urushiyama Hirokazu
Urushiyama Hirokazu
Affiliation and department: Research field (4):
Respiratory medicine
, Human pathology
, Healthcare management, medical sociology
, Molecular biology
Research keywords (6):
interstitial lung diseases
, lung pathology
, clinical epidemiology
, macrophage physiology
, fibroblast physiology
, extracellular matrix remodeling
Research theme for competitive and other funds (9): - 2024 - 2027 肺移植後慢性拒絶における線維化スイッチを標的とした新規治療戦略
- 2022 - 2025 線維芽細胞・マクロファージの相互作用に着目した肺線維化の病態解明
- 2021 - 2024 重症COVID-19合併ARDS・マクロファージ活性化症候群の新規治療戦略の確立
- 2021 - 2024 The role of macrophages in chronic rejection after lung transplantation and regulatioon of macrophage activities by FROUNT inhibition
- 2018 - 2021 Development of new treatment strategy for intractable severe respiratory disease focusing on the macrophage-FROUNT
- 2018 - 2021 Developments of effective diagnosis and therapeutic methods for pleuroparenchymal fibroelastosis using lung transplantation model
- 2016 - 2020 A role of Hippo pathway in pulmonary diseases
- 2015 - 2018 Analysis of predisposing factors on early fibrotic focus in interstitial pneumonia using microdissection
- 2014 - 2017 Elucidation of molecular mechanism of survivin in inflammatory lung disease and development of new gene therapy method
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Papers (72): -
Yugo Okabe, Etsuko Toda, Hirokazu Urushiyama, Yuya Terashima, Shinobu Kunugi, Yusuke Kajimoto, Mika Terasaki, Kouji Matsushima, Akira Saito, Yasuhiro Yamauchi, et al. Antifibrotic effect of disulfiram on bleomycin-induced lung fibrosis in mice and its impact on macrophage infiltration. Scientific reports. 2024. 14. 1. 23653-23653
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Aya Saihara-Yamaguchi, Hirokazu Urushiyama, Kosuke Makita, Shotaro Aso, Hideaki Watanabe, Akira Yokoyama, Takahiro Ando, Taisuke Jo, Nobuyasu Awano, Matsui Hiroki, et al. The association between the use of Shoseiryuto and reduction in intravenous steroid dose among adult inpatients with asthma exacerbation: A national database study in Japan. Respiratory investigation. 2024. 62. 6. 1053-1057
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Nobuyasu Awano, Taisuke Jo, Takehiro Izumo, Hirokazu Urushiyama, Hiroki Matsui, Kiyohide Fushimi, Hideaki Watanabe, Hideo Yasunaga. Safety of transbronchial lung cryobiopsy compared to transbronchial forceps biopsy in patients with diffuse lung disease: An observational study using a national database in Japan. Respiratory investigation. 2024. 62. 5. 844-849
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Takayoshi Enokido, Yoshihisa Hiraishi, Taisuke Jo, Hirokazu Urushiyama, Akira Saito, Satoshi Noguchi, Keisuke Hosoki, Takashi Ishii, Naoya Miyashita, Kensuke Fukuda, et al. Endoscopic reflux esophagitis and decline in pulmonary function in nonsmokers: A retrospective cohort study. Respiratory Investigation. 2024. 62. 4. 599-605
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Nobuyuki Yoshiyasu, Rei Matsuki, Masaaki Sato, Hirokazu Urushiyama, Etsuko Toda, Yasuhiro Terasaki, Masaki Suzuki, Aya Shinozaki-Ushiku, Yuya Terashima, Jun Nakajima. Disulfiram, an Anti-alcoholic Drug, Targets Macrophages and Attenuates Acute Rejection in Rat Lung Allografts. Transplant international : official journal of the European Society for Organ Transplantation. 2024. 37. 12556-12556
more... MISC (42): - 平石 尚久, 城 大祐, 長谷川 若恵, 坂本 幸世, 竹島 英之, 漆山 博和, 三谷 明久, 山内 康宏, 長瀬 隆英, 康永 秀生. DPCデータを用いた肺癌に対しての診断的気管支鏡の周術期死亡率の検討. 気管支学. 2017. 39. Suppl. S222-S222
- 國保 成暁, 寺崎 泰弘, 功刀 しのぶ, 漆山 博和, 寺崎 美佳, 清水 章. mTOR阻害薬肺障害における脂質代謝ストレスを介した肺胞上皮傷害の解明. 日本病理学会会誌. 2017. 106. 1. 294-294
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国土典弘, 本間之夫, 長瀬隆英, 杉原亨, 漆山博和, 石丸美穂, 宇田和晃. 大規模データを用いた運動器疾患・呼吸器疾患・がん・脳卒中等の臨床疫学・経済分析 がん治療のプロセス・アウトカム評価. 大規模データを用いた運動器疾患・呼吸器疾患・がん・脳卒中等の臨床疫学・経済分析 平成28年度 総括・分担研究報告書(Web). 2017
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Y. Terasaki, N. Kokuho, S. Kunugi, Y. Saito, M. Terasa, H. Urushiyama, A. Gemma. The Analyses Of Alveolar Epithelial Injury Through The Lipid Metabolic Stress In The Mammalian Target Of Rapamycin Inhibitor Induced Lung Disease. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2017. 195
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H. Takeshima, M. Horie, N. Miyashita, K. Makita, H. Matsuzaki, S. Noguchi, Y. Mikami, H. Urushiyama, A. Mitani, T. Nagase, et al. Transcriptome Analysis Revealed Interleukine-13 Signaling Pathway In Human Lung Fibroblasts. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2017. 195
more... Lectures and oral presentations (4): -
EFFECT OF DAI-KENCHU-TO ON COPD EXACERBATIONS IN ELDERLY PATIENTS: A RETROSPECTIVE STUDY USING A NATIONWIDE DATABASE IN JAPAN
(RESPIROLOGY 2018)
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Risk factors for acute exacerbation of interstitial pneumonia after surgery with general anesthesia
(EUROPEAN RESPIRATORY JOURNAL 2018)
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HIPPO PATHWAY EFFECTORS TAZ AND YAP FUNCTIONING AT DIFFERENT STAGES OF LUNG DEVELOPMENT
(RESPIROLOGY 2017)
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Clinico-pathological analysis of acute respiratory distress syndrome (ARDS)
(EUROPEAN RESPIRATORY JOURNAL 2012)
Work history (5): - 2024/03 - 現在 東京大学医学部附属病院 呼吸器内科 特任講師
- 2015/07 - 2024/03 The University of Tokyo Respiratory Medicine, Faculty of Medicine University Hospital
- 2015/04 - 2015/06 The University of Tokyo Respiratory Medicine, Faculty of Medicine University Hospital
- 2013/04 - 2015/03 Nippon Medical School
- 2009/04 - 2013/03 The University of Tokyo Graduate School of Medicine
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