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J-GLOBAL ID：201901006293830049   Update date: Feb. 25, 2025

Suzuki Hidefumi

スズキ ヒデフミ | Suzuki Hidefumi
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Affiliation and department：
Yokohama City University School of Medicine Medical Course , Molecular Biology

About Yokohama City University School of Medicine Medical Course , Molecular Biology


Job title： Lecturer
Homepage URL  (1)： https://ycu-molecularbiology.jp
Research field  (1)： Molecular biology
Research keywords  (6)： 液相分離 ,  Mediator複合体 ,  遺伝子発現制御 ,  核内構造体 ,  RNAポリメラーゼII ,  ヒストン修飾
Research theme for competitive and other funds  (4)：
  • 2022 - 2024 新生RNA鎖によるMED26液滴形成を介した転写制御機構の解明
  • 2020 - 2022 Elucidation of spatiotemporal regulatory mechanism of histone gene transcription through interaction of MED26 and nuclear bodies
  • 2016 - 2018 有糸分裂を乗り越えて遺伝子発現パターンを復元する転写制御機構の解明
  • 2013 - 2016 細胞傷害応答におけるTLPのp53活性化機構と応答配列認識機構の解明
Papers (25)：
  • Sanami Takada, Silvanna Gallo, Sebastian Silva, Hiroki Tanaka, Oscar Pincheira, Juan Zúñiga, Marcela Villarroel, Ximena Hidalgo, Joel Melo-Tanner, Hidefumi Suzuki, et al. A Novel AGR2 Variant Causing Aberrant Monomer-Dimer Equilibrium Leading to Severe Respiratory and Digestive Symptoms. Journal of clinical immunology. 2024. 45. 1. 55-55
  • Keisuke Noguchi†, Hidefumi Suzuki†, Ryota Abe†, Keiko Horiuchi, Rena Onoguchi-Mizutani, Nobuyoshi Akimitsu, Shintaro Ogawa, Tomohiko Akiyama, Yoko Ike, Yoko Ino, et al. Multi-omics analysis using antibody-based in situ biotinylation technique suggests the mechanism of Cajal body formation. Cell Reports. 2024
  • Kazuki Furugori, Hidefumi Suzuki, Ryota Abe, Keiko Horiuchi, Tomohiko Akiyama, Tomonori Hirose, Atsushi Toyoda, Hidehisa Takahashi. Chimera RNA transcribed from integrated HPV18 genome with adjacent host genomic region promotes oncogenic gene expression through condensate formation. Genes to cells : devoted to molecular & cellular mechanisms. 2024
  • Taishi Wada, Hiroshi Doi, Masaki Okubo, Mikiko Tada, Naohisa Ueda, Hidefumi Suzuki, Wakana Tominaga, Haruki Koike, Hiroyasu Komiya, Shun Kubota, et al. RNA foci in two bi-allelic RFC1 expansion carriers. Annals of neurology. 2023
  • Hidefumi Suzuki, Kazuki Furugori, Ryota Abe, Shintaro Ogawa, Sayaka Ito, Tomohiko Akiyama, Keiko Horiuchi, Hidehisa Takahashi. MED26-containing Mediator may orchestrate multiple transcription processes through organization of nuclear bodies. BioEssays : news and reviews in molecular, cellular and developmental biology. 2023. e2200178
ｍore...
MISC (13)：
  • 野口慶介, 鬼澤理紗, 阿部竜太, 池陽子, 仙石徹, 緒方一博, 井野洋子, 木村弥生, 鈴木秀文, 高橋秀尚. Elucidation of regulatory mechanism of the snRNA gene expression at Cajal body by LEC component ZC3H8. 日本薬学会年会要旨集(Web). 2024. 144th
  • 野口慶介, 鈴木秀文, 阿部竜太, 堀内恵子, 秋山智彦, 池陽子, 井野洋子, 木村弥生, 梁明秀, 梁明秀, et al. The multi-omics analysis of the components of nuclear bodies using antibody-based in situ biotinylation technique. 日本電気泳動学会シンポジウム講演要旨集. 2023. 73rd (CD-ROM)
  • 鈴木秀文, 阿部竜太, 池陽子, 古郡華月, 小川真太郎, 豊田敦, 鈴木穣, 井野洋子, 木村弥生, 秋山智彦, et al. メディエーター複合体の液滴による転写ユニティー制御機構の解明. 日本生化学会大会(Web). 2023. 96th
  • 野口慶介, 鈴木秀文, 阿部竜太, 池陽子, 井野洋子, 木村弥生, 梁明秀, 土井宏, 田中章景, 山口雄輝, et al. Identification of the component of Cajal body by multi-omics analysis using antibody-based in situ biotinylation technique, and elucidation of mechanism of Cajal body formation. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
  • 中居 佑介, 宮川 敬, 山岡 悠太郎, 鈴木 秀文, 高橋 秀尚, 木村 弥生, 梁 明秀. In situビオチン化法を用いたB型肝炎ウイルスのコアタンパク質と相互作用する宿主因子群の探索. 電気泳動. 2021. 65. Supple. s49-s49
ｍore...
Books (2)：
  • 分子生物学-ゲノミクスとプロテオミクス (田村隆明 監訳)
    東京化学同人 2018
  • 遺伝子発現制御機構 (田村隆明, 浦聖恵 編著)
    東京化学同人 2017
Lectures and oral presentations  (15)：
  • メディエーター複合体の液滴による転写ユニティー制御機構の解明
    (第96回日本生化学会大会 2023)
  • メディエーター複合体による新規の転写スピード調節機構の解明
    (第45回日本分子生物学会年会 2022)
  • A novel 3 Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies’ association with Histone locus bodies
    (2021)
  • メディエーターは2つの異なる核内凝集体を結びつけることによって転写終結を制御する
    (第42回日本分子生物学会年会 2019)
  • The role of Mediator and Little Elongation Complex in transcription termination
    (Cold Spring Harbor Laboratory Meeting 2019)
ｍore...
Education (1)：
  • 2013 - 2015 Chiba University Graduate School of Science
Professional career (1)：
  • 博士(理学) (千葉大学)
Work history (5)：
  • 2024/04 - 現在 Yokohama City University
  • 2019/04 - 現在 Yokohama City University
  • 2018/04 - 2019/03 国立がん研究センター研究所 腫瘍生物学分野 研究員
  • 2016/04 - 2018/03 Tokyo Institute of Technology School of Life Science and Technology
  • 2015/10 - 2016/03 Chiba University Graduate School of Science
Awards (2)：
  • 2016/03 - 千葉大学 千葉大学理学研究科長表彰 成績優秀者
  • 2013/03 - 千葉大学 千葉大学学長表彰 成績優秀者
Association Membership(s) (1)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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