Rchr
J-GLOBAL ID:201901007187306760   Update date: Feb. 01, 2024

Nishikai Tsubame (SHEN Yan)

Nishikai Tsubame (SHEN Yan)
Affiliation and department:
Research field  (1): Human pathology
Research keywords  (5): 生活習慣病 ,  糖尿病性潰瘍 ,  表皮幹細胞 ,  栄養生理 ,  糖尿病
Research theme for competitive and other funds  (5):
  • 2020 - 2023 effect of MNC-QQc on diabetic wound repair and its underlying mechanism
  • 2019 - 2021 糖尿病皮膚幹細胞による皮膚再生・破綻機構の解明
  • 2019 - 2021 新規血管再生マクロファージのメカニズム解析を通じた新規血管再生治療の開発
  • 2013 - 2016 Elucidation of the anti-thrombotic property of food component and its application for the development of functional food.
  • 2013 - 2014 シナモンの2型糖尿病ならびにエネルギー代謝改善効果とその作用メカニズムに関する研究
Papers (14):
  • Sen Jiang, Rie Ito-Hirano, Tsubame Nishikai-Yan Shen, Satoshi Fujimura, Hiroshi Mizuno, Rica Tanaka. Effect of MNCQQ Cells on Migration of Human Dermal Fibroblast in Diabetic Condition. Biomedicines. 2022. 10. 10
  • Tsubame (Y, Nishikai-Shen, Tomomi Hosono-Fukao, Toyohiko Ariga, Takashi Hosono, Taiichiro Seki. Cinnamon extract improves abnormalities in glucose tolerance by decreasing Acyl-CoA synthetase long-chain family 1 expression in adipocytes. Scientific Reports. 2022
  • Nishikai-Shen T, Tanaka R. Relationship between skin keloid pathogenesis and Endothelial Progenitor Cells: A review. Journal of Skin and Stem Cell. 2022. 8. 3. e117822
  • Tsubame Nishikai-Yan Shen, Makiko Kado, Hiroko Hagiwara, Satoshi Fujimura, Hiroshi Mizuno, Rica Tanaka. MMP9 secreted from mononuclear cell quality and quantity culture mediates STAT3 phosphorylation and fibroblast migration in wounds. Regenerative therapy. 2021. 18. 464-471
  • Nishikai-Shen T, Tanaka R. Effect of Quality and Quantity Cultured Peripheral Blood Mononuclear Cell (MNC-QQc) on Human Dermal Fibroblast Migration and its Underlying Mechanism in vitro. Wound repair and Regeneration. 2020. 28. 5. 6-6
more...
Lectures and oral presentations  (23):
  • 末梢血単核球由来細胞(MNC-QQ細胞)が皮膚線維芽細胞遊走に及ぼす影響の解明.
    (第30回日本形成外科学会基礎学術集会 2021)
  • 生体外増幅末梢血単核球(MNC-QQ細胞)が皮膚由来線維芽細胞遊走能に及ぼす分子メカニズムの解明
    (第29回日本形成外科学会基礎学術集会 2020)
  • 生体外増幅末梢血単核球(MNC-QQ細胞)の共培養による皮膚線維芽細胞遊走促進メカニズムの解明
    (第19回日本再生医療学会 2020)
  • 生体外増幅末梢血単核球(MNC-QQ細胞)の繊維芽細胞遊走促進効果及びそのメカニズム
    (第49回日本創傷治癒学会 2019)
  • 糖尿病性潰瘍においてM1/M2マクロファージ活性化による皮膚の再生機構の解明
    (日本再生医療学会 2015)
more...
Education (3):
  • 2008 - 2011 Nihon University
  • 2006 - 2008 Josai University Faculty of Pharmaceutical Sciences
  • 1999 - 2004 黒竜江中医薬大学 医学部 医学科
Work history (6):
  • 2018/04 - 現在 Juntendo University Faculty of Medicine
  • 2015/04 - 2018/03 Tokyo Medical and Dental University
  • 2014/04 - 2018/03 Nihon University
  • 2014/04 - 2015/03 Juntendo University Faculty of Medicine
  • 2011/04 - 2014/03 Nihon University College of Bioresource Sciences
Show all
Awards (2):
  • 2011/03 - Bioscience, Biotechnology, and Biochemistry 論文賞
  • 2009/10 - 日本栄養・食糧学会 優秀ポスター賞
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