Rchr
J-GLOBAL ID:201901007485494529
Update date: Mar. 07, 2024 Niwa Fumihiro
ニワ フミヒロ | Niwa Fumihiro
Affiliation and department: Job title:
Assistant Professor
Research field (4):
Pharmacology
, Neuroscience - general
, Biophysics
, Cell biology
Research keywords (9):
Neuroscience
, Cell Biology
, Neuropharmacology
, Super resolution imaging (PALM/STORM)
, single molecule imaging
, Biochemistry
, Biophysics
, genome editing (CRISPR/Cas)
, in utero electroporation
Research theme for competitive and other funds (9): - 2023 - 2025 Molecular basis of morphine analgesic tolerance by GPCR hetero-dimerisation
- 2018 - 2021 Inhibitory neurotransmitter release and receptor dynamics during synaptic transmission: real-time imaging at single molecule level - SynTrack (Project-ANR-17-CE13-0030)
- 2016 - 2017 The role of excitatory activity for the plasticity of inhibitory synapse
- 2016 - 2017 Regulatory mechanism of inhibitory synaptic plasticity by excitatory synaptic activity
- 2016 - 2017 The role of excitatory activity for the plasticity of inhibitory synapses
- 2013 - 2016 Regulatory mechanism of lateral diffusion of neurotrasmitter receptors by Ca2+
- 2012 - 2015 Regulatory mechanisms of inhibitory synapse
- 2013 - 2015 GABAergic synaptic regulation mechanism
- 2014 - Homeostatic regulation of GABA synapses through the control of receptor diffusion by IP3/Ca2+ signaling
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Papers (13): -
Hiroko Bannai, Fumihiro Niwa, Shigeo Sakuragi, Katsuhiko Mikoshiba. Inhibitory synaptic transmission tuned by Ca2+ and glutamate through the control of GABAAR lateral diffusion dynamics. Development, Growth & Differentiation. 2020
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Hiroko Bannai, Takafumi Inoue, Matsumi Hirose, Fumihiro Niwa, Katsuhiko Mikoshiba. Synaptic Function and Neuropathological Disease Revealed by Quantum Dot-Single-Particle Tracking. Neuromethods. 2020. 131-155
- Fumihiro Niwa. cAMP-EPAC-dependent regulation of gephyrin phosphorylation and GABAAR trapping at inhibitory synapses. iScience. 2019. 22. 453-465
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Bannai H, Hirose M, Niwa F, Mikoshiba K. Dissection of Local Ca2+ Signals in Cultured Cells by Membrane-targeted Ca2+ Indicators. Journal of visualized experiments : JoVE. 2019. 145
- Shigeo Sakuragi, Fumihiro Niwa, Yoichi Oda, Katsuhiko Mikoshiba, Hiroko Bannai. Astroglial Ca2+ signaling is generated by the coordination of IP3R and store-operated Ca2+- channels. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2017. 486. 4. 879-885
more... MISC (3): -
Hiroko Bannai, Fumihiro Niwa, Misa Arizono, Antoine Triller. Molecular mechanism underlying the inhibitory synaptic plasticity revealed by single molecule imaging. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S33-S33
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M. Arizono, H. Bannai, K. Nakamura, F. Niwa, M. Enomoto, T. Matsu-ura, A. Miyamoto, M. W. Sherwood, T. Nakamura, K. Mikoshiba. Receptor-selective diffusion barrier enhances sensitivity of astrocytic processes to metabotropic glutamate receptor stimulation. JOURNAL OF NEUROCHEMISTRY. 2012. 123. 116-116
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F. Niwa, H. Bannai, M. Arizono, K. Fukatsu, A. Triller, K. Mikoshiba. Gephyrin-independent GABAAR mobility and clustering during plasticity. JOURNAL OF NEUROCHEMISTRY. 2012. 123. 59-60
Lectures and oral presentations (7): -
Single molecular localization microscopy of GABAAR
(HKUST-ENS Joint Workshop on Inhibitory Synaptic Transmission 2021)
-
Molecular mechanisms of the regulation of inhibitory neurotransmitter receptors
(The 43rd Annual Meeting of the Molecular Biology Society of Japan 2020)
-
Regulation of Inhibitory synapse by cAMP-dependent pathway in Spinal cord neurons
(Symposium tribute to Maxime DAHAN 2019)
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Single particle tracking of GABAA receptor with super-resolution microscopy
(Life science seminar for student, HKUST 2018)
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Homeostatic regulation of GABA synapses through the control of receptor diffusion by IP3/Ca2+ signaling
(Jacques Monod Conference - Optical imaging of brain structure and function on multiple special scales)
more... Education (2): - 2007 - 2012 The University of Tokyo Graduate school of frontier sciences Department of medical sciences
- 2003 - 2007 The University of Tokyo Faculty of Science Department of Biology
Professional career (1): - Ph.D (The University of Tokyo)
Work history (7): Association Membership(s) (4):
The Japanese Pharmacological Society
, THE JAPAN NEUROSCIENCE SOCIETY
, The Japanese Society for Neurochemistry
, THE BIOPHYSICAL SOCIETY OF JAPAN
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