2019 - 2024 Novel approach focusing on the tight junction-based paracellular barrier combined with the apical barrier toward understanding and manipulating epithelial barriers
2018 - 2020 The Elucidation of tumorigenesis mechanisms through signal transduction starting from tight junction.
2014 - 2016 AMP-activated protein kinase regulates the function of tight junction.
Papers (17)：
Gen Shiratsuchi, Satoshi Konishi, Tomoki Yano, Yuichi Yanagihashi, Shogo Nakayama, Tatsuya Katsuno, Hiroka Kashihara, Hiroo Tanaka, Kazuto Tsukita, Koya Suzuki, et al. Dual-color live imaging unveils stepwise organization of multiple basal body arrays by cytoskeletons. EMBO Reports. 2024
Kazuto Tsukita, Manabu Kitamata, Hiroka Kashihara, Tomoki Yano, Ikuko Fujiwara, Timothy F Day, Tatsuya Katsuno, Jaewon Kim, Fumiko Takenaga, Hiroo Tanaka, et al. Phase separation of an actin nucleator by junctional microtubules regulates epithelial function. Science advances. 2023. 9. 7. eadf6358
Shogo Nakayama, Tomoki Yano, Toshinori Namba, Satoshi Konishi, Maki Takagishi, Elisa Herawati, Tomoki Nishida, Yasuo Imoto, Shuji Ishihara, Masahide Takahashi, et al. Planar cell polarity induces local microtubule bundling for coordinated ciliary beating. The Journal of cell biology. 2021. 220. 7
Kazuto Tsukita, Tomoki Yano, Atsushi Tamura, Sachiko Tsukita. Reciprocal Association between the Apical Junctional Complex and AMPK: A Promising Therapeutic Target for Epithelial/Endothelial Barrier Function?. International journal of molecular sciences. 2019. 20. 23
H. Kanoh, T. Yano, M. Uji, A. Tamura, S. Tsukita. TJ-MAP4 up-regulate MLC-phosphorylation by binding to MLC, ZO1 and tubulin at tight junction. MOLECULAR BIOLOGY OF THE CELL. 2016. 27
