Rchr
J-GLOBAL ID:201901008256943251   Update date: Jul. 28, 2023

Ueda Atsushi

ウエダ アツシ | Ueda Atsushi
Affiliation and department:
Research field  (1): Pharmaceuticals - chemistry and drug development
Research keywords  (2): ペプチド ,  Organic Chemistry
Research theme for competitive and other funds  (4):
  • 2023 - 2026 EおよびZ選択的ペプチドステープリング法の開発と応用
  • 2020 - 2023 ペプチド側鎖環化による新規二次構造の創出と制御法の開発
  • 2018 - 2020 ジ置換アミノ酸を利用した新規ペプチドフォールドマーの設計と合成
  • 2016 - 2018 コンフォメーション制御と分子認識を基盤とした架橋ペプチド触媒の創製
Papers (30):
  • Makoto Oba, Mika Shibuya, Yuto Yamaberi, Hidetomo Yokoo, Satoshi Uchida, Atsushi Ueda, Masakazu Tanaka. An Amphipathic Structure of a Dipropylglycine-Containing Helical Peptide with Sufficient Length Enables Safe and Effective Intracellular siRNA Delivery. Chemical & Pharmaceutical Bulletin. 2023. 71. 3. 250-256
  • Atsushi Ueda, Yui Makura, Sana Kakazu, Takuma Kato, Tomohiro Umeno, Kazuhiro Hirayama, Mitsunobu Doi, Makoto Oba, Masakazu Tanaka. E-Selective Ring-Closing Metathesis in α-Helical Stapled Peptides Using Carbocyclic α,α-Disubstituted α-Amino Acids. Organic Letters. 2022. 24. 4. 1049-1054
  • Kazuki Sato, Tomohiro Umeno, Atsushi Ueda, Takuma Kato, Mitsunobu Doi, Masakazu Tanaka. Asymmetric 1,4-Addition Reactions Catalyzed by N-Terminal Thiourea-Modified Helical l -Leu Peptide with Cyclic Amino Acids. Chemistry - A European Journal. 2021. 27. 43. 11216-11220
  • Yui Makura, Atsushi Ueda, Takuma Kato, Akihiro Iyoshi, Mei Higuchi, Mitsunobu Doi, Masakazu Tanaka. X-ray Crystallographic Structure of α-Helical Peptide Stabilized by Hydrocarbon Stapling at i,i + 1 Positions. International Journal of Molecular Sciences. 2021. 22. 10. 5364-5364
  • Atsushi Ueda, Mei Higuchi, Kazuki Sato, Tomohiro Umeno, Masakazu Tanaka. Design and Synthesis of Helical N-Terminal l-Prolyl Oligopeptides Possessing Hydrocarbon Stapling. Molecules. 2020. 25. 20. 4667-4667
more...
MISC (74):
  • 佐藤和樹, 梅野智大, 上田篤志, 土井光暢, 加藤巧馬, 田中正一. N末をチオウレアで修飾したヘリカルペプチド触媒による不斉マイケル付加反応. 創薬懇話会講演要旨集. 2021. 2021
  • 上田篤志, 上田篤志, 真倉唯, PI Jinhong, 田中正一, 上西潤一, 上西潤一. Stereoselective synthesis of (+)-5-thiosucrose via β-selective glycosidation of D-psicofuranose. 日本薬学会年会要旨集(Web). 2021. 141st
  • 真倉唯, 上田篤志, 梅野智大, 加藤巧馬, 平山和浩, 土井光暢, 大庭誠, 田中正一. E-selective ring-closing metathesis for i, i+4 stapled peptides. 日本薬学会年会要旨集(Web). 2021. 141st
  • 佐藤和樹, 梅野智大, 上田篤志, 土井光暢, 加藤巧馬, 田中正一. Asymmetric 1,4-addition reactions using N-terminal thiourea-modified helical peptide-catalysts. 日本薬学会年会要旨集(Web). 2021. 141st
  • 上田篤志, 上田篤志, 真倉唯, 山下隆則, 西村優里, 田中正一, 上西潤一, 上西潤一. β-Stereoselective glycosidation of D-psicofuranose. 日本糖質学会年会要旨集. 2020. 39th
more...
Patents (1):
Lectures and oral presentations  (109):
  • キラルな三員環状ジ置換アミノ酸を含むAibペプチドのコンフォメーション解析
    (第60回化学関連支部合同九州大会 2023)
  • 架橋部位を持つ五員環状アミノ酸によるAib配列ペプチドの二次構造変化
    (日本ケミカルバイオロジー学会第17回年会 2023)
  • Stereocontrolled synthesis of 5-thiosucrose with regioselective protection of D-allulofuranose
    (The 7th Gratama Workshop 2023)
  • Stereoselective glycosidation of D-fructofuranose and its synthetic application
    (The 7th Gratama Workshop 2023)
  • Synthesis of 5-thiosucrose from D-allulose and investigation of protecting groups
    (Rare Sugar Congress 2023 2023)
more...
Education (3):
  • 2007 - 2010 Kyoto Pharmaceutical University
  • 2005 - 2007 Kyoto Pharmaceutical University
  • 2001 - 2005 Kyoto Pharmaceutical University Pharmaceutical Sciences Pharmaceutical Biology
Professional career (1):
  • 博士(薬学) (京都薬科大学)
Work history (7):
  • 2020/06 - 現在 Nagasaki University
  • 2019/02 - 2020/05 Nagasaki University
  • 2017/04 - 2019/02 Nagasaki University
  • 2014/02 - 2017/03 Nagasaki University Graduate School of Biomedical Sciences
  • 2013/11 - 2014/02 Harvard University
Show all
Awards (3):
  • 2023/03 - 令和4年度長崎県科学技術奨励賞
  • 2019/12 - 公益社団法人 有機合成化学協会 塩野義製薬 研究企画賞
  • 2018/06 - 公益財団法人 宇部興産学術振興財団 第58回学術奨励賞
Association Membership(s) (3):
American Chemical Society ,  THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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