Research field (4):
General surgery, pediatric surgery
, Immunology
, Developmental biology
, Immunology
Research theme for competitive and other funds (1):
2021 - 2023 初期T前駆細胞に由来する胸腺内樹状細胞が果たす役割の解明
Papers (35):
Haruka Wada, Ryo Otsuka, Wilfred T V Germeraad, Tomoki Murata, Toru Kondo, Ken-Ichiro Seino. Tumor cell-induced macrophage senescence plays a pivotal role in tumor initiation followed by stable growth in immunocompetent condition. Journal for immunotherapy of cancer. 2023. 11. 11
Anand RP, Layer JV, Heja D, Takayuki Hirose, Grace Lassiter, Daniel Firl, Paragas VB, Akkad A, Sagar Chhangawala, Robert Colvin, et al. Design and testing of a humanized porcine donor for xenotransplantation. Nature. 2023
Tomoki Murata, Naoki Hama, Tomoki Kamatani, Akihiro Mori, Ryo Otsuka, Haruka Wada, Ken-Ichiro Seino. Induced pluripotent stem cell-derived hematopoietic stem and progenitor cells induce mixed chimerism and donor-specific allograft tolerance. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2023. 23. 9. 1331-1344
Grace Lassiter, Ryo Otsuka, Takayuki Hirose, Ivy Rosales, Ahmad Karadagi, Toshihide Tomosugi, Abbas Dehnadi, Hang Lee, Robert B. Colvin, Jason Baardsnes, et al. TNX-1500, a crystallizable fragment-modified anti-CD154 antibody, prolongs nonhuman primate renal allograft survival. American Journal of Transplantation. 2023
Han N, Wada H, Kobayashi T, Otsuka R, Ken-ichiro Seino. A mechanism of IL-34-induced resistance against cytotoxic anti-cancer therapies such as radiation by X-ray and chemotherapy by Oxaliplatin. Oncoimmunology. 2023
Ryo Otsuka, Haruka Wada, Ken-ichiro Seino. IL-34, the rationale for its expression in physiological and pathological conditions. SEMINARS IN IMMUNOLOGY. 2021. 54