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J-GLOBAL ID：201901013068013968 Update date: Jan. 30, 2024

Kanako Miyazaki

ミヤザキカナコ | Kanako Miyazaki

Affiliation and department：

Research field (1)： Developmental dentistry

Research theme for competitive and other funds (5)：

2021 - 2025 上皮-間葉ネットワークにおける器官運命決定機構の解明とその応用
2020 - 2022 The mechanism of ameloblast differentiation associated with apicobasal polarity induced by topological conversion.
2018 - 2020 The analysis of PKP1 as a novel transcriptional factor via Wnt signal pathway
2016 - 2018 A novel Wnt signaling pathway in ameloblast differentiation during tooth development
2015 - 2018 The mechanism of cell fate determination in epithelial-mesenchymal interaction during tooth development

Papers (11)：

Yao Fu, Kanako Miyazaki, Yuta Chiba, Keita Funada, Tomomi Yuta, Tian Tian, Kanji Mizuta, Jumpei Kawahara, Ling Zhang, Daniel Martin, et al. Identification of GPI-anchored protein LYPD1 as an essential factor for odontoblast differentiation in tooth development. The Journal of biological chemistry. 2023. 104638-104638
Tomomi Yuta, Tian Tian, Yuta Chiba, Kanako Miyazaki, Keita Funada, Kanji Mizuta, Yao Fu, Jumpei Kawahara, Tsutomu Iwamoto, Ichiro Takahashi, et al. Development of a novel ex vivo organ culture system to improve preservation methods of regenerative tissues. Scientific reports. 2023. 13. 1. 3354-3354
Tian Tian, Kanako Miyazaki, Yuta Chiba, Keita Funada, Tomomi Yuta, Kanji Mizuta, Yao Fu, Jumpei Kawahara, Xue Han, Yuna Ando, et al. An ex vivo organ culture screening model revealed that low temperature conditions prevent side effects of anticancer drugs. Scientific reports. 2022. 12. 1. 3093-3093
Keita Funada, Keigo Yoshizaki, Kanako MIyazaki, Xue Han, Tomomi Yuta, Tian Tian, Kanji Mizuta, Yao Fu, Tsutomu Iwamoto, Aya Yamada, et al. microRNA-875-5p plays critical role for mesenchymal condensation in epithelial-mesenchymal interaction during tooth development. Scientific Reports. 2020. 10. 1
Xue Han, Keigo Yoshizaki, Tian Tian, Kanako Miyazaki, Ichiro Takahashi, Satoshi Fukumoto. Mouse Embryonic Tooth Germ Dissection and Ex vivo Culture Protocol. BIO-PROTOCOL. 2020. 10. 3

MISC (1)：

FU Yao, 宮崎佳奈子, 千葉雄太, 吉崎恵悟, 鮒田啓太, 湯田智美, TIAN Tian, 水田敢士, 川原純平, 福本敏, et al. Identification of pre-odontoblast specific GPI-anchored protein Lypd1 and it regulates cell differentiation in developing tooth. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th

Lectures and oral presentations (4)：

着接合因子ZO-1による歯原性上皮細胞の増殖および分化に与える影響
(第76回日本矯正歯科学会学術大会 2018)
歯に特異的に発現するmiR875-5pの同定と発現パターン解析
(第76回日本矯正歯科学会学術大会 2017)
基底膜分子NephronectinはRGD領域を介してエナメル芽細胞の分化制御に関与する
(第76回日本矯正歯科学会学術大会 2017)
PKP1 regulates ameloblast differentiation via the cell adhesion
(International Association for Dental Research 2017)

Professional career (1)：

Work history (4)：

Awards (4)：

2022/10 - 歯科基礎医学会モリタ賞 GPI アンカー型タンパク質 Lypd1 は,前象牙芽細胞特異的に発現し象牙芽細胞分化を制御する
2021/11 - 第80回日本矯正歯科学会学術大会&第5回国際会議学術大会優秀発表賞抗がん剤シクロホスファミドの歯胚に与える影響と副作用回避法の検索
2019/11 - 公益社団法人日本矯正歯科学会第78回日本矯正歯科学会学術大会優秀演題発表賞 PKP1の歯原性上皮細胞における密着結合因子ZO-1の局在制御機構
2017/10 - 公益社団法人日本矯正歯科学会第76回日本矯正歯科学会学術大会優秀発表賞アレンドロネートの周期的静脈投与を受けている成長期骨形成不全症患者3症例の顎顔面形態の特徴

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