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J-GLOBAL ID:201901014136336343   Update date: Feb. 18, 2025

Hirata Hiroaki

ヒラタ ヒロアキ | Hirata Hiroaki
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Affiliation and department:
Job title: Professor
Homepage URL  (1): https://pressio-neurobrain.org
Research field  (2): Biophysics ,  Cell biology
Research keywords  (6): メカノバイオロジー ,  細胞増殖 ,  細胞運動 ,  細胞形態形成 ,  細胞接着 ,  細胞骨格
Research theme for competitive and other funds  (7):
  • 2024 - 2025 細胞間引張力の人為操作による表皮がん細胞の増殖抑制・分化誘導法の開拓と分子機序の解明
  • 2021 - 2024 プレッシオ脳神経科学の促進・発展
  • 2021 - 2024 Compressive stress against brain tumors: its effect on tumor cell growth and the underlying molecular mechanism
  • 2020 - 2023 Tissue deformation-dependent regulation of cell proliferation: distinct roles of cell-substrate and cell-cell adhesions
  • 2019 - 2021 細胞間接着構造に働く力の操作により表皮癌細胞の増殖を抑制する
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Papers (43):
  • Kishio Furuya, Hiroaki Hirata, Takeshi Kobayashi, Hiroshi Ishiguro, Masahiro Sokabe. Volume-regulated anion channels conduct ATP in undifferentiated mammary cells and promote tumorigenesis in xenograft nude mouse. Frontiers in Cell and Developmental Biology. 2025. 12. 1519642-1519642
  • Shinya Taniguchi, Takeru Torii, Toshiyuki Goto, Kohei Takeuchi, Rine Katsumi, Mako Sumida, Sunmin Lee, Sugimoto Wataru, Masaya Gessho, Katsuhiko Itoh, et al. Bioinformatic Analysis of Actin-Binding Proteins in the Nucleolus During Heat Shock. Genes. 2024. 15. 12. 1580-1580
  • Hiroki Katsuta, Masahiro Sokabe, Hiroaki Hirata. From stress fiber to focal adhesion: a role of actin crosslinkers in force transmission. Frontiers in Cell and Developmental Biology. 2024. 12. 1444827-1444827
  • Takeru Torii, Wataru Sugimoto, Katsuhiko Itoh, Natsuki Kinoshita, Masaya Gessho, Toshiyuki Goto, Ikuno Uehara, Wataru Nakajima, Yemima Budirahardja, Daisuke Miyoshi, et al. Loss of p53 function promotes DNA damage-induced formation of nuclear actin filaments. Cell Death & Disease. 2023. 14. 11. 766-766
  • Hiroki Katsuta, Satoru Okuda, Kazuaki Nagayama, Hiroaki Machiyama, Satoru Kidoaki, Masashi Kato, Masahiro Sokabe, Takaki Miyata, Hiroaki Hirata. Actin crosslinking by α-actinin averts viscous dissipation of myosin force transmission in stress fibers. iScience. 2023. 26. 3. 106090-106090
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MISC (17):
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Books (2):
  • 細胞のマルチスケールメカノバイオロジー
    森北出版 2017 ISBN:9784627691414
  • メカノバイオロジー : 細胞が力を感じ応答する仕組み
    化学同人 2015 ISBN:9784759817218
Awards (1):
  • 2014/04 - American Physiological Society APSselect
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