Hirokawa Yoshimi

Affiliation and department：

Research field (1)： Pharmaceuticals - chemistry and drug development

Research theme for competitive and other funds (4)：

2014 - 2019 Synthesis and Antibacterial Activity of new compounds derived from natural antibiotics
2011 - 2015 Design, Synthesis and Antibacterial Activity of Novel Pleuromutilin Derivatives
2009 - 2011 Development of antioxidant with lignan skeleton
2006 - 2007 Synthetic Study of HIF-1α Inhibitor, Manassantin B

Papers (27)：

Kenji Arimitsu, Yoshimi Hirokawa, Yuriko Ikegawa, Akiko Tanba, Yuki Ueda, Taiga Kashihara, Naruhiro Atarashi, Ryoto Yoshida, Yosuke Matsuo, Naoyoshi Maezaki. Synthesis of 2’,4-Dibromo-2,4’-bithiazole Using Novel Long-range Halogen Dance Reaction. ChemistrySelect. 2023
Naoyoshi Maezaki, Takuji Magata, Yoshimi Hirokawa, Yuki Rokuhara, Ryota Nakayama, Rina Takahashi, Masashi Nogami, Yasuto Tai, Tomoki Imahori, Takanori Hashizume. Synthesis and Evaluation of Dendroamide A and Three Regioisomeric Analogs Having a Reversed Azole Ring as P-Glycoprotein Inhibitors. HETEROCYCLES. 2021. 102. 5. 900-900
Magata Takuji, Hirokawa Yoshimi, Moriguchi Yusuke, Yokoi Ryosuke, Nojiri Shotaro, Miyazaki Ryota, Akasako Sayuri, Takahashi Rina, Nishida Munetaka, Hakoda Junya, et al. Concise and stereoselective synthesis of 2,5-and 2,4-disubstituted thiazole amino acid subunits for synthesizing thiazole-containing peptides. TETRAHEDRON LETTERS. 2019. 60. 10. 718-720
Takuji Magata, Yoshimi Hirokawa, Aya Furokawa, Kazuhisa Takeuchi, Yoshiaki Ohtomo, Toshitaka Kino, Jun Kominami, Yuto Nakai, Maria Kitamura, Naoyoshi Maezaki. Highly diastereoselective synthesis of 2-(1-N-Boc-aminoalkyl)thiazole-5-carboxylates by reduction of tert-butylsulfinyl ketimines. Chemical and Pharmaceutical Bulletin. 2018. 66. 4. 416-422
Takuji Magata, Saeka Nagano, Takuya Endo, Jun Kawaida, Shiho Nagaoka, Yoshimi Hirokawa, Naoyoshi Maezaki. Enantioselective synthesis of methyl 2-[1-[(tert-butoxycarbonyl)amino]ethyl]-4-methyloxazole-5-carboxylate by a one-pot enamide cyclization. TETRAHEDRON LETTERS. 2017. 58. 37. 3628-3630

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MISC (48)：

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Patents (37)：

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