Research theme for competitive and other funds (3):
2023 - 2026 Osteoclast fusion and regulation by DC-STAMP and OC-STAMP
2020 - 2023 活性型ビタミンD3誘導体:エルデカルシトールの骨破壊性疾患の治療への応用
2019 - 2021 Elucidation of bone-destroying diseases by controlling inflammatory cytokine
Papers (30):
Mehmet Cekuc, Yasemin Ergul, Alexa Pius, Makarcyzk Meagan, Issei Shinohara, Masatoshi Murayama, Yosuke Susuki, Chao Ma, Mayu Morita, Simon Chow, et al. Metformin Modulates Cell Oxidative Stress to Mitigate Corticosteroid-Induced Suppression of Osteogenesis in a 3D Model. Journal of Inflammation Research. 2024. Volume 17. 10383-10396
Qi Gao, Mehmet Sertac Cekuc, Yasemin Sude Ergul, Alexa K. Pius, Issei Shinohara, Masatoshi Murayama, Yosuke Susuki, Chao Ma, Mayu Morita, Simon Kwoon-Ho Chow, et al. 3D Culture of MSCs for Clinical Application. Bioengineering. 2024. 11. 12. 1199-1199
Issei Shinohara, Atsuyuki Inui, Katherine Hwang, Masatoshi Murayama, Yosuke Susuki, Tomohiro Uno, Qi Gao, Mayu Morita, Simon Kwoon-Ho Chow, Masanori Tsubosaka, et al. Leveraging AI models for lesion detection in osteonecrosis of the femoral head and T1-weighted MRI generation from radiographs. Journal of Orthopaedic Research. 2024
Simon Kwoon-Ho Chow, Qi Gao, Alexa Pius, Mayu Morita, Yasemin Sude Ergul, Masatoshi Murayama, Issei Shinohara, Mehmet Sertac Cekuc, Chao Ma, Yosuke Susuki, et al. The advantages and shortcomings of stem cell therapy for enhanced bone healing. Tissue engineering. Part C, Methods. 2024
Tomoya Soma, Ryotaro Iwasaki, Yuiko Sato, Tami Kobayashi, Eri Ito, Tatsuaki Matsumoto, Atsushi Kimura, Kana Miyamoto, Morio Matsumoto, Masaya Nakamura, et al. Osteonecrosis development by tooth extraction in zoledronate treated mice is inhibited by active vitamin D analogues, anti-inflammatory agents or antibiotics. Scientific Reports. 2022. 12. 1
Osteonecrosis due to bacterial infection following bisphosphonate treatment is required an elevation of pro-inflammatory cytokine levels.
(The 38th The American Society for Bone and Mineral Research 2016)
Smad4 In Osteoclasts Reduce Bone Mass By Inhibiting Osteoclast Differentiation.
(International Association of Oral and Maxillofacial Surgeons. 2015)
Education (2):
2014 - 2017 慶応義塾大学医学部 医学研究科博士課程
2003 - 2009 Showa University School of Dentistry Division of Dentistry
Awards (2):
2017/10 - Outstanding Poster Presentation Award Osteonecrosis due to bacterial infection following bisphosphonate treatment is required an elevation of pro-inflammatory cytokine levels.