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J-GLOBAL ID：201901016748549446   Update date: Sep. 05, 2024

Ashino Shigeru

アシノ シゲル | Ashino Shigeru
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Affiliation and department：
Kyoto University Graduate School of Medicine

About Kyoto University Graduate School of Medicine


Research field  (2)： Immunology ,  Respiratory medicine
Research keywords  (7)： 気管支喘息 ,  ヘルパーT細胞 ,  自然リンパ球 ,  難治性喘息 ,  RSウイルス ,  ライノウイルス ,  インフルエンザウイルス
Research theme for competitive and other funds  (4)：
  • 2021 - 2024 Viral nucleic acid components-based mechanisms of RSV-induced asthma exacerbation and the strategy for controlling the pathogensis
  • 2017 - 2023 免疫系と神経系のクロストークに着目した気管支喘息重篤化機構の解明と制御法開発
  • 2016 - 2019 The mechanisms of asthma exacerbation induced by viral infection and the development of strategy for controlling the pathogenesis(Fostering Joint International Research)
  • 2015 - 2017 Elucidation of mechanisms for developing new strategies on a viral infection-induced steroid-resistant asthma
Papers (18)：
  • Atsushi Kurokawa, Mitsuko Kondo, Ken Arimura, Shigeru Ashino, Etsuko Tagaya. Less airway inflammation and goblet cell metaplasia in an IL-33-induced asthma model of leptin-deficient obese mice. Respiratory research. 2021. 22. 1. 166-166
  • Meiqin Wang, Matthew J Strand, Bruce J Lanser, Carah Santos, Kreso Bendelja, Jennifer Fish, Elizabeth A Esterl, Shigeru Ashino, Jordan K Abbott, Vijaya Knight, et al. Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children. PloS one. 2020. 15. 6. e0233563
  • Zaim E, Ashino S, Osaka T, Yanagisawa N, Yagi J. Effect of Cholecalciferol in Food Allergy Mouse Model Is Associated with Decrease of CD69+ CD4+ T Cells. Journal of nutritional science and vitaminology. 2019. 65. 2. 113-122
  • Katsuyuki Takeda, Fangkun Ning, Joanne Domenico, Masakazu Okamoto, Shigeru Ashino, Sang-Ha Kim, Yi Yeong Jeong, Yoshiki Shiraishi, Naohiro Terada, Everett Rand Sutherland, et al. Activation of p70S6 Kinase-1 in Mesenchymal Stem Cells Is Essential to Lung Tissue Repair. Stem cells translational medicine. 2018. 7. 7. 551-558
  • Katsuyuki Takeda, Tracy L Webb, Fangkun Ning, Yoshiki Shiraishi, Daniel P Regan, Lyndah Chow, Mia J Smith, Shigeru Ashino, Amanda M Guth, Sophie Hopkins, et al. Mesenchymal Stem Cells Recruit CCR2+ Monocytes To Suppress Allergic Airway Inflammation. Journal of immunology (Baltimore, Md. : 1950). 2018. 200. 4. 1261-1269
ｍore...
MISC (26)：
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Lectures and oral presentations  (13)：
  • Double But Not Single-Stranded RNA derived from Respiratory Syncytial Virus Exacerbates Allergen-Induced Airway Inflammation
    (American Thoracic Society International Conference 2020 2020)
  • Double But Not Single-Stranded RNA Exacerbates Allergen-Induced Airway Hyperresponsiveness and Airway Inflammation
    (2020)
  • レプチン欠損肥満マウス(ob/ob mice)における気道過敏性の検討
    (日本呼吸器学会誌(Web) 2019)
  • The Crucial Roles of Neurokinin A and Neurokinin Receptor 2 Signaling in Asthma Exacerbation Induced by a Viral Component, Double-Stranded RNA
    (The 67th Annual Meeting of Japanese Society of Allergology 2018)
  • The Effects of Viral Components, Single-Stranded RNA and Double-Stranded RNA, on Allergen-Induced Airway Hyperresponsiveness and Airway Inflammation.
    (American Thoracic Society International Conference 2018 2018)
ｍore...
Professional career (1)：
  • 博士 (医学) (北海道大学)
Work history (6)：
  • 2021/02 - 現在 Kyoto University
  • 2019/07 - 2021/01 東京女子医科大学
  • 2013/11 - 2019/06 東京女子医科大学
  • 2018/01 - 2019/03 National Jewish Health,
  • 2010/04 - 2013/10 National Jewish Health, Division of Cell Biology, Department of Pediatrics, Postdoctoral fellow (PI: Erwin W. Gelfand)
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Association Membership(s) (5)：
American Thoracic Society ,  American Academy of Allergy Asthma and Immunology ,  European Respiratory Society ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  JAPANESE SOCIETY OF ALLERGOLOGY
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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