Rchr
J-GLOBAL ID:201901017020016928   Update date: Jul. 03, 2024

Akimoto Miho

Akimoto Miho
Affiliation and department:
Research field  (2): Cell biology ,  Tumor biology
Research keywords  (2): 腫瘍生物学 ,  細胞生物学
Research theme for competitive and other funds  (5):
  • 2022 - 2025 肥満および老化の脂肪幹細胞由来のIL-33が膵がんの悪性進展に及ぼす影響の解析
  • 2019 - 2023 低酸素による可溶性IL-33受容体の発現低下が大腸がん悪性進展に及ぼす影響の解析
  • 2017 - 2023 Expression of Parathyroid-specific Novel lncRNA and Paucity of CaSR Characterize an Ectopic PTH-producing Tumor.
  • 2016 - 2020 Analysis of antitumor effects of adiponectin receptor agonists on pancreatic cancer
  • 2012 - 2015 Antimetastatic effects of a soluble IL-33 receptor and its utility as a prognostic biomarker in colorectal cancer.
Papers (26):
  • Noriyuki Okudaira, Mi-Ho Akimoto, Takao Susa, Miho Akimoto, Harumi Hisaki, Masayoshi Iizuka, Hiroko Okinaga, Julio A Almunia, Noboru Ogiso, Tomoki Okazaki, et al. Accumulation of senescent cells in the adrenal gland induces hypersecretion of corticosterone via IL1β secretion. Aging cell. 2024. e14206
  • Miho Akimoto, Takao Susa, Noriyuki Okudaira, Nobuko Koshikawa, Harumi Hisaki, Masayoshi Iizuka, Hiroko Okinaga, Keizo Takenaga, Tomoki Okazaki, Mimi Tamamori-Adachi. Hypoxia induces downregulation of the tumor-suppressive sST2 in colorectal cancer cells via the HIF-nuclear IL-33-GATA3 pathway. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 18. e2218033120
  • Miho Akimoto, Takao Susa, Noriyuki Okudaira, Harumi Hisaki, Masayoshi Iizuka, Hiroko Okinaga, Tomoki Okazaki, Mimi Tamamori-Adachi. A Novel LncRNA PTH-AS Upregulates Interferon-Related DNA damage resistance Signature genes and Promotes Metastasis in Human Breast Cancer Xenografts. Journal of Biological Chemistry. 2022. 102065-102065
  • Keizo Takenaga, Nobuko Koshikawa, Miho Akimoto, Yasutoshi Tatsumi, Jason Lin, Makiko Itami, Hiroki Nagase. MCT4 is induced by metastasis-enhancing pathogenic mitochondrial NADH dehydrogenase gene mutations and can be a therapeutic target. Scientific reports. 2021. 11. 1. 13302-13302
  • Keizo Takenaga, Miho Akimoto, Nobuko Koshikawa, Hiroki Nagase. Obesity reduces the anticancer effect of AdipoRon against orthotopic pancreatic cancer in diet-induced obese mice. Scientific reports. 2021. 11. 1. 2923-2923
more...
MISC (7):
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Work history (2):
  • 2017/07 - 現在 Teikyo University School of Medicine
  • 2006/05 - 2017/06 Shimane University Faculty of Medicine
Association Membership(s) (2):
日本分子生物学会 ,  THE JAPANESE CANCER ASSOCIATION
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