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J-GLOBAL ID:201901019063129060   Update date: Feb. 14, 2025

Seki Akihiro

セキ アキヒロ | Seki Akihiro
Affiliation and department:
Research field  (1): Gastroenterology
Research theme for competitive and other funds  (6):
  • 2022 - 2025 非アルコール性脂肪肝炎における局所環境動態に基づく間葉系幹細胞治療の機序解明
  • 2020 - 2023 Study of liver restorative therapy for a murine nonalcoholic steatohepatitis model by the administration of immune-suppressive fractions of autologous adipose tissue-derived stromal cells
  • 2020 - 2022 非アルコール性脂肪肝炎による腸管免疫・癌微小環境動態と大腸癌への影響の解明
  • 2019 - 2021 Therapeutic effects and mechanisms of inflammatory bowel disease using immunomodulatory effects of iPS cell-derived mesenchymal stem cells
  • 2014 - 2017 Analysis of characteristics of cellular subfractions in adipose tissue-derived stromal cells for development of liver repair/regenerative therapy
Show all
Papers (84):
  • Takeshi Terashima, Hidenori Kido, Noboru Takata, Tomoyuki Hayashi, Akihiro Seki, Hidetoshi Nakagawa, Kouki Nio, Tadashi Toyama, Noriho Iida, Shinya Yamada, et al. Phase II Study of Atezolizumab and Bevacizumab Combination Therapy for Patients with Advanced Hepatocellular Carcinoma Previously Treated with Lenvatinib. Cancers. 2025. 17. 2
  • Masaki Miyazawa, Masahiro Yanagi, Tomoyoshi Chiba, Kazuki Nagai, Hidenori Kido, Saiho Sugimoto, Masaki Nishitani, Noriaki Orita, Noboru Takata, Tomoyuki Hayashi, et al. Metachronous Pancreatic Cancer with Pancreaticobiliary Maljunction Diagnosed Five Years after Cholecystectomy for Gallbladder Cancer, in Which Follow-up Imaging was Possible Until the Onset of Cancer: A Case Report and Review of the Literature. Internal medicine (Tokyo, Japan). 2025
  • Takeshi Terashima, Kouki Nio, Naohiko Koshikawa, Makoto Ueno, Tadashi Toyama, Masaki Miyazawa, Tomoyuki Hayashi, Akihiro Seki, Hidetoshi Nakagawa, Noriho Iida, et al. Serum laminin γ2 monomer as a novel diagnostic and prognostic marker for pancreatic ductal adenocarcinoma. BJC reports. 2025. 3. 1. 2-2
  • Alessandro Nasti, Shingo Inagaki, Tuyen Thuy Bich Ho, Akihiro Seki, Keiko Yoshida, Kosuke Satomura, Yoshio Sakai, Shuichi Kaneko, Taro Yamashita. Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer. Molecular oncology. 2025
  • Takeshi Terashima, Tatsuya Yamashita, Kuniaki Arai, Noboru Takata, Tomoyuki Hayashi, Akihiro Seki, Hidetoshi Nakagawa, Kouki Nio, Noriho Iida, Shinya Yamada, et al. Comprehensive genomic profiling for advanced hepatocellular carcinoma in clinical practice. Hepatology international. 2024
more...
MISC (39):
  • 関 晃裕, 中沼 伸一, 岡崎 充善, 山下 太郎, 八木 真太郎. 肝移植における免疫抑制療法のベストプラクティスは? 肝移植後の免疫抑制剤使用に伴う腎機能障害の検討. 移植. 2024. 59. 総会臨時. 207-207
  • 小川 憲彦, 関 晃裕, 山下 太郎. 肝疾患に対する再生医療:現状と課題 脂肪組織由来間葉系幹細胞によるMASHの肝局所環境におけるIL17および肝星細胞を介した肝細胞死の軽減機序についての検討. 肝臓. 2024. 65. Suppl.2. A589-A589
  • 関 晃裕, 山下 竜也, 中沼 伸一, 寺島 健志, 荒井 邦明, 八木 真太郎, 山下 太郎. 消化器移植医療の現状と今後の展開 脳死肝移植待機登録の適応拡大に照らした肝細胞癌患者の検討. 日本消化器病学会雑誌. 2024. 121. 臨増総会. A195-A195
  • 林智之, 西谷雅樹, 織田典明, 宮澤正樹, 高田昇, 岡藤啓史, 玉井利克, 中河秀俊, 関晃裕, 丹尾幸樹, et al. 潰瘍性大腸炎の内視鏡的寛解予測におけるLRGの検討~活動性評価目的の内視鏡検査は不要となるか~. 日本消化器病学会雑誌(Web). 2023. 120
  • 山本信, 林智之, 鷹取元, 山下竜也, 井城敬一郎, 竹内勇太, 千葉智義, 木戸秀典, 松尾俊紀, 三浦雅, et al. 難治性胃食道逆流症に対して内視鏡的噴門部粘膜焼灼術を施行した一例. Endoscopic Forum for Digestive Disease. 2023. 39. 1
more...
Lectures and oral presentations  (22):
  • Current status and treatment with artificial liver support system for ALF and ACLF in our hospital
    (APASL2024 Kyoto 2024)
  • The evaluation for causes and status of fatty liver after liver transplantation.
    (APASL2024 Kyoto 2024)
  • Mesenchymal stromal cells improves liver function in MASH by reducing the ER stress induced by hepatic stellate cells in hepatocytes.
    (APASL2024. Kyoto 2024)
  • The current situation of hilar cholangiocarcinoma and the possibility of liver transplantation
    (2023)
  • 脂肪組織由来間葉系幹細胞によるNASHの肝局所環境における小胞体ストレス軽減を介した治療効果の検討
    (日本消化器関連学会週間 (JDDW) 2023)
more...
Education (2):
  • 2007 - 2014 Kanazawa University
  • 1998 - 2005 Toyama Medical and Pharmaceutical University
Work history (4):
  • 2022/04 - 現在 金沢大学附属病院 消化器内科 助教
  • 2019/11 - 2022/03 Kanazawa University
  • 2016/04 - 2019/03 Icahn School of Medicine at Mount Sinai gastroenterology post doctoral fellow
  • 2014/04 - 2016/03 金沢大学
Awards (2):
  • 2016/02 - Rotary International 2610 district Global grant Scholarship
  • 2013/10 - The Japan Society of Hepatology 12th Otsuka award
Association Membership(s) (6):
日本移植学会 ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  The Japan Society of Hepatology ,  JAPAN GASTROENTEROLOGICAL ENDOSCOPY SOCIETY ,  JAPANESE SOCIETY OF GASTROENTEROLOGY ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE
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