Research theme for competitive and other funds (27)：
2024 - 2027 Early Diagnosis of Pancreatic Cancer Based on the Mechanism of Development of Precancerous Lesions and the Emergence of Invasive Buds during Carcinogenesis
2024 - 2027 膵癌分子サブタイプに関わるncRNAの探索と分子診断および創薬への応用
2024 - 2026 m3C修飾によるRNA分解と癌維持機構への関与
2022 - 2026 Strategy for an early diagnosis by modeling the developmental and evolutionary paths of human pancreatic cancer
2021 - 2025 Study of novel stress response mechanism in human cells
2023 - 2025 膵癌オルガノイドを用いた構造異常RNAの探索と機能解析
2023 - 2024 メチル化酵素による脂肪滴形成と膵癌維持機構の解明
2021 - 2024 The clinical applications of long non-coding RNA and extracellular vesicles to diagnosis and therapy for pancreatic cancer
2021 - 2024 x
2022 - 2023 癌転移に関わるチオールメチル化酵素標的因子の網羅的同定
2021 - 2023 x
2020 - 2023 Early diagnosis of pancreatic cancer based on diversity of field defect and molecular genetic approach
2021 - 2023 RNA品質管理機構による構造異常RNAの産生制御と癌増殖機構との関連
2021 - 2022 RNA品質管理機構と異常RNAによる癌発生機構の理解
2022 - 膵癌初期発生におけるクローン進化多様性の解明
2022 - DNA変異とRNA 発現解析を統合した新規膵癌体液診断法の開発
2021 - DNA変異とRNA発現解析を統合したマルチレイヤー膵癌体液診断法の開発
2021 - RNAから視たp53制御機構の解明
2020 - 長鎖ncRNAによるプロテアソーム制御を介したp53依存的な腫瘍形成能維持機構
2017 - 2019 x
2015 - 2018 Mechanism of colorectal tumorigenesis caused by lncRNA-Transcription factor complex
2018 - 膵がん早期診断・先制医療の実現に向けたサーベイランスシステム
2015 - 2017 x
2016 - lncRNA-転写因子複合体が制御する大腸癌の腫瘍形成能維持機構の解明
2013 - 2015 Molecular mechanisms for p53 inactivation by EHF in colorectal cancer.
2008 - 2009 x
がん幹細胞を標的とした分子標的薬の創製
Show all
Papers (37)：
Taniue K, C, Sugawara A, Zeng C, Han H, Gao X, Shimoura Y, Ozeki N A, Onoguchi-Mizutani R, Seki M, et al. The MTR4/hnRNPK complex surveils aberrant polyadenylated RNAs with multiple exons. Nature Communications. 2024
Kenji Takahashi, Tatsutoshi Inuzuka, Yuta Shimizu, Kazuki Sawamoto, Kenzui Taniue, Yusuke Ono, Fumi Asai, Kazuya Koyama, Hiroki Sato, Hidemasa Kawabata, et al. Liquid Biopsy for Pancreatic Cancer by Serum Extracellular Vesicle-Encapsulated Long Noncoding RNA HEVEPA. Pancreas. 2024
Kenzui Taniue, Takeaki Oda, Tomoatsu Hayashi, Yuki Kamoshida, Yasuko Takeda, Anzu Sugawara, Yuki Shimoura, Lumi Negishi, Takeshi Nagashima, Mariko Okada-Hatakeyama, et al. LncRNA ZNNT1 induces p53 degradation by interfering with the interaction between p53 and the SART3-USP15 complex. PNAS Nexus. 2023
Maeda Chiho, Yusuke Ono, Akihiro Hayashi, Kenji Takahashi, Kenzui Taniue, Rika Kakisaka, Miyuki Mori, Takahiro Ishii, Hiroki Sato, Tetsuhiro Okada, et al. Multiplex digital PCR assay to detect multiple KRAS and GNAS mutations associated with pancreatic carcinogenesis from minimal specimen amounts. The Journal of Molecular Diagnostics. 2023. 25. 6. 367-377
Taniue K, Akimitsu N. The hidden layer of RNA variants. RNA Structure and Function - Springer book 2023. 2023
Circulating extracellular vesicle-encapsulated long non-coding RNAs obtained via liquid biopsy are potential biomarkers for pancreatic ductal adenocarcinoma
(31st United European Gastroenterology Week (UEG Week 2023) 2023)
2022 - International Journal of Molecular Sciences Top View Papers of IJMS in 2022 RNA Exosome Component EXOSC4 Amplified in Multiple Cancer Types Is Required for the Cancer Cell Survival
2021 - The FEBS Journal The Top Downloaded Article 2021 Aberrant Phase Separation in Cancer.
2021 - International Journal of Molecular Sciences Highly Cited Papers of IJMS The Functions and Unique Features of LncRNAs in Cancer Development and Tumorigenesis.
