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J-GLOBAL ID:201901021307228389   Update date: Dec. 25, 2024

Hayashi Sachiko

ハヤシ サチコ | Hayashi Sachiko
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Affiliation and department:
Research field  (3): Genetics ,  Molecular biology ,  Cell biology
Research keywords  (5): tRNA ,  Translation ,  Ribosome ,  Yeast ,  mRNA localization
Research theme for competitive and other funds  (4):
  • 2024 - 2025 令和6年度熊本大学発生医学研究所 共同研究
  • 2024 - 2025 tRNAイントロンと多彩な細胞機能を繋ぐ因子の同定
  • 2020 - 2023 出芽酵母のイントロン含有tRNA(Ic-tRNA)が支えるリボソーム関連品質管理
  • 2008 - 2010 出芽酵母における新規細胞質局在化RNAの局在化機構と生理的意義の解明
Papers (14):
  • Sachiko Hayashi. Variation of tRNA modifications with and without intron dependency. Frontiers in Genetics. 2024. 15. 1460902
  • Sachiko Hayashi, Kazumi Iwamoto, Tohru Yoshihisa. A non-canonical Puf3p-binding sequence regulates CAT5/COQ7 mRNA under both fermentable and respiratory conditions in budding yeast. PLOS ONE. 2023. 18. 12. e0295659-e0295659
  • Sachiko Hayashi. Multiple layers of gene-expression regulatory mechanisms during fermentation and respiration. New Advances in Saccharomyces. 2023
  • Sachiko Hayashi, Masaya Matsui, Ayano Ikeda, Tohru Yoshihisa. Six identical tRNATrpCCA genes express a similar amount of mature tRNATrpCCA but unequally contribute to yeast cell growth. Bioscience, biotechnology, and biochemistry. 2022. 86. 10. 1398-1404
  • Sachiko Hayashi. Puf3p facilitates fermentative mitochondrial functions via monosome-enriched nuclear-encoded mitochondrial mRNAs in budding yeast. BioRxiv. 2022
more...
MISC (1):
  • Sachiko Hayashi. Ribosome quality control via intron-containing tRNA (ic-tRNA) in budding yeast. The CELL. 2022. 54. 12. 40-43
Books (1):
  • Multiple layers of gene-expression regulatory mechanisms during fermentation and respiration
    IntechOpen 2023 ISBN:9780854661282
Lectures and oral presentations  (28):
  • Cellular stress from tRNALeuCAA intron deletion in budding yeasts
    (MBSJ2024 2024)
  • tRNA intron in tRNALeuCAA genes is required for cellular proteostasis in budding yeasts
    (29th tRNA Conference 2024)
  • tRNAイントロンの多面的役割
    (オルガネラ研究会2024 2024)
  • Regulation of RPS7/eS7 mRNA paralogs via their 3'-UTR in budding yeast
    (The 4th Kansai RNA Club 2024)
  • tRNA intron and protein folding: how so close?
    (The 25th Annual Meeting of the RNA Society of Japan 2024)
more...
Education (3):
  • 2007 - 2011 Kumamoto University Graduate School of Science and Technology Division of Science (Doctoral Program)
  • 2006 - 2007 Kumamoto University Graduate School of Science and Technology Division of Science (Master's Programs)
  • 2002 - 2006 Kumamoto University Faculty of Science
Professional career (1):
  • Ph.D. (Kumamoto University)
Work history (5):
  • 2021 - 現在 University of Hyogo Graduate School of Science Junior Assistant Professor
  • 2017 - 現在 RIKEN Iwasaki RNA Systems Biochemistry Laboratory Visiting scientist
  • 2016 - 2021 University of Hyogo Graduate School of Life Science Junior Assistant Professor
  • 2011 - 2015 University of Freiburg Institute for Biochemistry and Molecular Biology Postdoctoral Researcher
  • 2008 - 2011 Kumamoto University Graduate School of Science and Technology JSPS Fellow
Association Membership(s) (5):
The RNA Society ,  YEAST GENETICS SOCIETY OF JAPAN ,  THE RNA SOCIETY OF JAPAN ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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