Nakama Takahiro

ナカマタカヒロ | Nakama Takahiro

Affiliation and department：
Job title：特任助教

Research field (2)： Molecular biochemistry , Inorganic and coordination chemistry

Research theme for competitive and other funds (3)：

2024 - 2025 膜タンパク質を担持する超分子ナノディスクの創製
2024 - 2025 かご型錯体の孤立空間を活用したタンパク質多量体界面に結合する新薬候補化合物探索法の開発
2021 - 2024 Structural analysis of protein–ligand weak interactions through co-encapsulation into a self-assembled spherical cage

Papers (11)：

Hiroyuki Tamura, Takahiro Nakama, Anouk Rossen, Hiroshi Ishikita, Makoto Fujita. Organic Solvent-Induced Structural Changes in a Protein Confined in a Giant Coordination Cage. Chemistry Letters. 2024
Yusuke Takezawa, Lingyun Hu, Takahiro Nakama, Mitsuhiko Shionoya. Metal-dependent activity control of a compact-sized 8-17 DNAzyme based on metal-mediated unnatural base pairing. Chemical Communications. 2024
Yusuke Takezawa, Keita Mori, Wei-En Huang, Kotaro Nishiyama, Tong Xing, Takahiro Nakama, Mitsuhiko Shionoya. Metal-mediated DNA strand displacement and molecular device operations based on base-pair switching of 5-hydroxyuracil nucleobases. Nature Communications. 2023. 14. 1
Takahiro Nakama, Anouk Rossen, Risa Ebihara, Maho Yagi-Utsumi, Daishi Fujita, Koichi Kato, Sota Sato, Makoto Fujita. Hysteresis behavior in the unfolding/refolding processes of a protein trapped in metallo-cages. Chemical science. 2023. 14. 11. 2910-2914
Daishi Fujita, Ryoto Suzuki, Yuya Fujii, Mayu Yamada, Takahiro Nakama, Akimasa Matsugami, Fumiaki Hayashi, Jing-Ke Weng, Maho Yagi-Utsumi, Makoto Fujita. Protein stabilization and refolding in a gigantic self-assembled cage. Chem. 2021. 7. 10. 2672-2683

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MISC (3)：

Takahiro Nakama. 注目の論文: マイクロ ED でゲスト分子を捉えた. 2023. 78. 2. 60-61
Takahiro Nakama. Bismuth-catalyzed redox reactions. Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 2021. 79. 8. 788-789
Yusuke Takezawa, Takahiro Nakama, Mitsuhiko Shionoya. "核酸無機材料". 2020. 98-106

Lectures and oral presentations (52)：

Elucidating Protein-Ligand Weak Interactions by Spatial Confinement in Spherical Coordination Cages
(45th International Conference on Coordination Chemistry (ICCC2024) 2024)
Protein Encapsulation in Spherical Coordination Cages for Structural Analysis of Fleeting Intermediates
(45th International Conference on Coordination Chemistry (ICCC2024) 2024)
NMR Analysis of Protein-Lipid Weak Interactions by Confinement in Self-Assembled Metal Coordination Cages
(2024)
Analysis of protein-lipid weak interactions by encapsulation in M12L24 spherical coordination cages
(2024)
巨大かご型錯体への空間捕捉を活用したタンパク質構造解析
(日本薬学会第144年会 2024)

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Education (2)：

2015 - 2020 The University of Tokyo Graduate School of Science Department of Chemistry
2011 - 2015 The University of Tokyo Faculty of Science Department of Chemistry

Work history (1)：

2020/04 - The University of Tokyo, Graduate School of Engineering Applied Chemistry Project Assistant Professor

Awards (6)：

2019/04 - The University of Tokyo 19th BioUT Poster Award
2018/08 - Japan Society of Coordination Chemistry 68th JSCC Conference Student Presentation Award
2018/06 - 16th Symposium on Host-Guest and Supramolecular Chemistry Poser Award
2018/03 - The Chemical Society of Japan Student Presentation Award, 98th CSJ meeting
2017/10 - International Symposium on Center of Excellence for Innovative Material Sciences Based on Supramolecules Best Poster Award

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