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J-GLOBAL ID:202001002103065533   Update date: Apr. 11, 2025

Onodera Shoko

Onodera Shoko
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Affiliation and department:
Job title: associate professor
Research keywords  (4): Hh singling ,  基底細胞母斑症候群 ,  Gorlin症候群 ,  疾患iPS細胞
Research theme for competitive and other funds  (11):
  • 2024 - 2027 骨芽細胞核におけるRunx2-Lamin Aの遺伝子発現制御機構の解明
  • 2021 - 2024 Multi-layered mutations in patient with Gorlin syndrome may affect the phenotype
  • 2019 - 2022 新概念に基づく骨芽細胞分化制御機構の解明と鎖骨頭蓋骨異形成症に対する治療薬の開発
  • 2018 - 2021 Elucidation of osteoblast mineralization mechanism using McCunealbright syndrome iPS cells
  • 2018 - 2021 Organization of nuclear architecture and gene expression during osteoblast differentiation
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Papers (43):
  • Akiko Saito, Kazuaki Nagayama, Hiroyuki Okada, Shoko Onodera, Natsuko Aida, Takashi Nakamura, Takashi Sawada, Hironori Hojo, Shigeaki Kato, Toshifumi Azuma. Downregulation of Nesprin1 by Runx2 deficiency is critical for the development of skeletal laminopathy-like pathology. Proceedings of the National Academy of Sciences. 2025. 122. 15
  • Itsuki Hideshima, Yuriko Nakamura, Shoko Onodera, Yoshihiko Akashi, Kenichi Matsuzaka, Masayuki Takano, Takeshi Nomura, Akira Katakura, Toshifumi Azuma. Analysis of Germline and Somatic Mutation in Patients With Developmental Odontogenic Cysts Using Targeted Gene Panel. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 2025. 54. 1. 12-21
  • Fernanda Aragão Felix, Jing Zhou, Dongfang Li, Shoko Onodera, Qing Yu. Endogenous IL-22 contributes to the pathogenesis of salivary gland dysfunction in the non-obese diabetic model of Sjögren's syndrome. Molecular immunology. 2024. 173. 20-29
  • Haruka Nakazato, Shoko Onodera, Natsuko Aida, Masahiro Furusawa, Toshifumi Azuma. Comprehensive analysis of transcription factors involved in odontoblast differentiation mechanism. Medical molecular morphology. 2024
  • Hiroyuki Ogura, Takashi Nakamura, Takenobu Ishii, Akiko Saito, Shoko Onodera, Akira Yamaguchi, Yasushi Nishii, Toshifumi Azuma. Mechanical stress-induced FGF-2 promotes proliferation and consequently induces osteoblast differentiation in mesenchymal stem cells. Biochemical and biophysical research communications. 2023. 684. 149145-149145
more...
MISC (62):
  • 小野寺晶子, 中村ゆり子, 秀島樹, 野村武史, 片倉朗, 東俊文. Gorlin症候群遺伝子パネルを用いた未診断患者への応用. 日本臨床分子形態学会総会・学術集会講演プログラム・要旨集. 2023. 55th
  • 岡田寛之, 岡田寛之, 岡田寛之, 照井悠太, 小俣康徳, 小俣康徳, 関真秀, 谷彰一郎, 谷彰一郎, 谷彰一郎, et al. 運動器発のサブセルラーシーケンスで,細胞生物学の常識に挑む. 日本骨代謝学会学術集会プログラム抄録集(CD-ROM). 2023. 41st
  • 秀島樹, 中村ゆり子, 小野寺晶子, 森田奈那, 森田奈那, 野村武史, 高野正行, 東俊文, 片倉朗. Gorlin症候群診断遺伝子パネルを用いた顎骨嚢胞の遺伝子変異解析. 日本口腔科学会学術集会プログラム・抄録集. 2023. 77th
  • 中村 ゆり子, 小野寺 晶子, 秀島 樹, 高野 正行, 片倉 朗, 野村 武史, 東 俊文. Gorlin症候群の遺伝子変異におけるHedgehogシグナル活性の解明. 歯科学報. 2022. 122. 2. 232-232
  • 秀島 樹, 中村 ゆり子, 小野寺 晶子, 野村 武史, 東 俊文, 片倉 朗. 歯原性角化嚢胞における分子遺伝学的検討. 歯科学報. 2022. 122. 2. 239-239
more...
Professional career (1):
  • Doctor of Dentistry (Tokyo Dental College)
Work history (6):
  • 2024/04 - 現在 東京大学医学部臨床医工学 客員研究員
  • 2023/04 - 現在 Tokyo Dental College Dept. of biochemstry associate professor
  • 2017/11 - 2023/03 Tokyo Dental College Department of Biochemistry Senior Assistant Professor
  • 2016/04 - 2023/03 東京大学医学部臨床医工学 客員研究員
  • 2021/07 - 2023/01 The Forsyth institute visiting investigator
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Awards (3):
  • 2023/09 - 日本臨床分子形態学会 第55回日本臨床分子形態学会最優秀演題賞 Gorlin症候群遺伝子パネルを用いた未診断患者への応用
  • 2023/09 - 55th Japanese Society of Clinical Molecular Morphology Best Paper Award The concurrent stimulation of Wnt and FGF8 signaling induce differentiation of dental mesenchymal cells into odontoblast-like cells
  • 2018/09 - 日本臨床分子形態学会 第50回日本臨床分子形態学会優秀演題賞 Gorlin症候群患者由来iPS細胞の骨芽細胞分化能の異常
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