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Research theme for competitive and other funds (1)：
Papers (39)：
MISC (15)：
Work history (5)：
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- 2020 - 2023 KRASの超生理的活性化を標的としたKRAS増幅胃癌フェロトーシス誘導療法の開発
- Yu Hidaka, Norihide Jo, Osamu Kikuchi, Masaru Fukahori, Takeshi Sawada, Yutaka Shimazu, Masaki Yamamoto, Kohei Kometani, Miki Nagao, Takako E Nakajima, et al. Effect of pre-vaccination blood and T-cell phenotypes on antibody responses to COVID-19 mRNA vaccine. International Immunology. 2025
- Yuki Kondo, Shinya Ohashi, Chikatoshi Katada, Yukie Nakai, Yoshihiro Yamamoto, Masashi Tamaoki, Osamu Kikuchi, Atsushi Yamada, Kenshiro Hirohashi, Yosuke Mitani, et al. Aldh2 and the tumor suppressor Trp53 play important roles in alcohol-induced squamous field cancerization. Journal of Gastroenterology. 2025
- Tomohiro Kondo, Osamu Kikuchi, Yoshihiro Yamamoto, Tomohiko Sunami, Yafeng Wang, Keita Fukuyama, Tomoki Saito, Hideto Nakahara, Sachiko Minamiguchi, Masashi Kanai, et al. Colorectal cancer harboring EGFR kinase domain duplication response to EGFR tyrosine kinase inhibitors. The oncologist. 2024
- Kohei Kometani, Takaaki Yorimitsu, Norihide Jo, Erina Yamaguchi, Osamu Kikuchi, Masaru Fukahori, Takeshi Sawada, Yoshitaka Tsujimoto, Ayana Sunami, Mengqian Li, et al. Booster COVID-19 mRNA vaccination ameliorates impaired B-cell but not T-cell responses in older adults. Frontiers in immunology. 2024. 15. 1455334-1455334
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Trang H. Nguyen Vu, Osamu Kikuchi, Shinya Ohashi, Tomoki Saito, Tomomi Ida, Yukie Nakai, Yang Cao, Yoshihiro Yamamoto, Yuki Kondo, Yosuke Mitani, et al. Combination therapy with
WEE1 inhibition and trifluridine/tipiracil against esophageal squamous cell carcinoma. Cancer Science. 2023. 114. 12. 4664-4676
- Masahiro Yoshioka, Shinya Ohashi, Tomomi Ida, Yukie Nakai, Osamu Kikuchi, Yusuke Amanuma, Jun'ichi Matsubara, Atsushi Yamada, Shin'ichi Miyamoto, Manabu Muto. EGFR inhibitors exert different effects on epithelial-like and mesenchymal-like esophageal squamous carcinoma cells. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2016. 31. 31-32
- 吉岡 正博, 大橋 真也, 菊池 理, 玉置 将司, 松原 淳一, 森 由希子, 宮本 心一, 武藤 学. 上皮様、間葉様の食道扁平上皮がんに対するEGFR阻害剤による分化誘導効果. 日本癌学会総会記事. 2016. 75回. P-1248
- Osamu Kikuchi, Kiichiro Baba, Shinya Ohashi, Manabu Muto. Establishment of a 5-fluorouracil-resistant esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase gene amplification. CANCER RESEARCH. 2016. 76
- Osamu Kikuchi, Shinya Ohashi, Yukie Nakai, Yusuke Amanuma, Masahiro Yoshioka, Shin'ichi Miyamoto, Mitsuteru Natsuizaka, Hiroshi Nakagawa, Tsutomu Chiba, Manabu Muto. Notch3-mediated squamous cell differentiation shows anti-tumor effect on esophageal squamous cell carcinoma as well as reduces its resistance to 5-Fluorouracil. CANCER RESEARCH. 2015. 75
- 菊池 理, 大橋 真也, 天沼 裕介, 横山 顕礼, 宮本 心一, 松本 繁巳, 武藤 学. Notch3過剰発現による食道扁平上皮分化誘導は腫瘍造成能及び5FU抵抗性を抑制する. 日本食道学会学術集会プログラム・抄録集. 2015. 69回. 179-179
- 2023/06 - 現在 Kyoto University Center for Cancer Immunotherapy and Immunobiology Associate Professor
- 2020/07 - 2023/06 Kyoto University Hospital Clinical Oncology Assistant Professor
- 2020/01 - 2020/07 Kyoto University Hospital Clinical Bio-Resource Center Assistant Professor
- 2019/10 - 2020/01 Kyoto University Hospital Clinical Oncology Attending physician
- 2016/10 - 2019/09 Dana-Farber Cancer Institute Medical Oncology Postdoctral Fellow
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