Rchr
J-GLOBAL ID：202001007993075028
Update date: May. 30, 2024
Sakama Akihiro
サカマ アキヒロ | Sakama Akihiro
Affiliation and department：
Job title：
Research Associate
Research field (2)：
Synthetic organic chemistry
, Analytical chemistry
Research keywords (6)：
Synthetic Organic Chemistry
, Stereoselective Synthesis
, Multistep Synthesis
, Natural Product Chemistry
, terpenoid
, Fluorescent Probe
Research theme for competitive and other funds (2)：
- 2023 - 2029 Creation of an assay platform for the determination of health risks and hormonal activities of man-made chemicals based on bioluminescent cell arrays
- 2020 - 2023 マグネシウムイオン動態のオルガネラ選択的可視化を可能にする新規蛍光プローブの開発
Papers (7)：
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Akihiro Sakama, Hyemin Seo, Joji Hara, Yutaka Shindo, Yuma Ikeda, Kotaro Oka, Daniel Citterio, Yuki Hiruta. Rational design of pH-responsive near-infrared spirocyclic cyanines: the effects of substituents and the external environment. Chemical Communications. 2024
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Rei Kumada, Akihiro Sakama, Yutaka Shindo, Yuzuka Kuronuma, Naoko Iwasawa, Daniel Citterio, Kotaro Oka, Yuki Hiruta. Development of Phosphinate Ligand-Based Low-Affinity Ca2+ Fluorescent Probes and Application to Intracellular Ca2+ Imaging. Analytical Chemistry. 2023
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Tomoka Yoshii, Akihiro Sakama, Kazuyoshi Kanamori, Kazuki Nakanishi, Hiroaki Imai, Daniel Citterio, Yuki Hiruta. Fabrication process development and basic evaluation of eggshell-based column packing material for reversed-phase preparative separation. Journal of Chromatography A. 2023
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Mariko Orioka, Masatoshi Eguchi, Yuki Mizui, Yuma Ikeda, Akihiro Sakama, Qiaojing Li, Hideaki Yoshimura, Takeaki Ozawa, Daniel Citterio, Yuki Hiruta. A Series of Furimazine Derivatives for Sustained Live-Cell Bioluminescence Imaging and Application to the Monitoring of Myogenesis at the Single-Cell Level. Bioconjugate Chemistry. 2022. 33. 3. 496-504
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Akihiro Sakama, Rika Kameshima, Yuko Motohashi, Wataru Sumida, Yuta Unno, Keisuke Yoshida, Akihiro Ogura, Ken-ichi Takao. Stereoselective Synthesis of the Tricyclic Core of (-)-Callophycoic Acid A. The Journal of Organic Chemistry. 2020. 85. 5. 3245-3264
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MISC (2)：
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Akihiro Sakama, Mariko Orioka, Yuki Hiruta. Current advances in the development of bioluminescent probes toward spatiotemporal trans-scale imaging. Biophysics and Physicobiology. 2024. 21. Supplemental. e211004
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Akihiro Sakama, Akihiro Ogura, Keisuke Yoshida, Ken-ichi Takao. The Stereoselective Construction of All-Carbon Quaternary Stereocenters by Allylations and Its Application to Synthetic Studies of Natural Products. Journal of Synthetic Organic Chemistry, Japan. 2020. 78. 11. 1039-1047
Lectures and oral presentations (14)：
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ホスフィン酸リガンドに基づく低親和性Ca2+蛍光プローブの開発と細胞内Ca2+イメージングへの応用
(日本化学会第104春季年会(2024) 2024)
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Development of Phosphinate Ligand-based Low-Affinity Calcium Ion Fluorescent Probe for Ratiometric Measurement and Application to Intracellular Imaging
(RSC Tokyo International Conference 2023 2023)
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ホスフィン酸リガンドを有する蛍光プローブの開発と細胞イメージングへの応用
(第2回生命金属科学シンポジウム 2023)
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細胞内遊離マグネシウムイオン動態の選択的可視化を可能にする新規蛍光プローブの開発
(日本化学会第103春季年会(2023) 2023)
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Development of near-infrared fluorescent probe for organelle-specific detection of magnesium ion
(The 2021 International Chemical Congress of Pacific Basin Societies 2021)
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Education (3)：
- 2015 - 2020 Keio University Graduate School of Science and Technology Doctoral Program in Fundamental Science and Technology
- 2013 - 2015 Keio University Graduate School of Science and Technology Master's Program in Fundamental Science and Technology
- 2009 - 2013 Keio University Faculty of Science and Technology Department of Applied Chemistry
Professional career (1)：
- Ph.D in Engineering (Keio University)
Work history (3)：
- 2024/04 - 現在 The University of Tokyo Institute of Industrial Science (Department of Materials and Environmental Science) Research Associate
- 2020/05 - 2024/03 Keio University Department of Applied Chemistry, Faculty of Science and Technology Researcher
- 2020/04 - 2020/04 Keio University Department of Applied Chemistry, Faculty of Science and Technology Associated Visiting Researcher
Association Membership(s) (2)：
The Chemical Society of Japan
, The Society of Synthetic Organic Chemistry, Japan
