Seki Minoru

セキミノル | Seki Minoru

Affiliation and department：
Job title： Professor
Research theme for competitive and other funds (31)：

2020 - 2023 Demonstration of an integrated cell processing device that revolutionizes minimally invasive prenatal diagnosis
2020 - 2023 Precise reconstruction of complex biological tissue by flexible processing of "porous" matrix
2019 - 2022 Demonstration of a multiscale fluid separator that revolutionizes next-generation liquid biopsy
2017 - 2020 Demonstration of integrated microfluidic system that realizes selection / placement / 3-dimensional complex of cells
2016 - 2019 Reproduction processes of three-dimensional tissues based on particulate matrices

2015 - 2019 Formation of functional 3D tissues suitable for transplantation by liver and pancreatic cells

2016 - 2018 Development of Assay Systems for Cancer Cell Invasion Using Microfabricated Hierarchical Hydrogels

2015 - 2018 A Proposal on the Microfabrication Method of Fluorine Polymer and Its Application to Microfluidic Devices

2014 - 2017 Development and Application of Integrated Micro Cell-Sorting System Enabling High-Throughput Treatment

2011 - 2016 High speed cell assembly using microfluidics

2011 - 2016 Research Management

2011 - 2013 Development of continuous separation systems using monodisperse microbubbles

2010 - 2012 Polymer surface morphology control by reactive ion etching and its application

2008 - 2011 Investigation of Rapid and Continuous Separation Principle for Micro/Nano Structures Using Hydrodynamic Methods

2004 - 2006 Construction of Micro/Nano-Reactor Array Using Low-Volume Liquid Dispenser

2001 - 2003 診断用集積チップ開発のための基礎的研究

1999 - 2001 Reaction, Separation and Dtection of Biomacromolecules using Disposable Microchips

1998 - 2001 Construction of double targeting system

1998 - 2000 Development of Surfactant Modified Enzymes That Show High Activity in Organic Media.

1997 - 1999 Development of Continuous Production Process for Anti-Cancer Drug by Plant Cell Culture with Medium Recycling

1997 - 1998 Enhancement of Somatic Embryogenesis by a Novel Control Method of Phytohormone

1996 - 1997 Modeling of Pigment Glycoside Production and Its Regulation by Genetic Transformation in Plant Cell Culture.

1996 - 1996 圧力センサーによる細胞増殖圧の測定と固定化細胞の漏出機構のモデル化

1995 - 1996 Evaluation of Effect of Hydrodynamic Shear Stress on Cultured Plant Cells

1995 - 1995 植物培養細胞のコンディショニング効果の解明と有用物質生産への応用

1994 - 1995 Development of Production Process for Anti-Cancer Drug Taxol with Immobilized Plant Cell Culture.

1994 - 1994 多孔質粒子の共固定による固定化生細胞の活性向上

1993 - 1994 不定胚の高密度培養法の開発

1992 - 1993 Research on Plant Cell Culture with Ultrasonic Permeabilization for the Release of Intracellular Product

1990 - 1991 Research on the Effect of Light Irradiation on Metabolite Production using Cultured Plant Cell

1988 - 1989 Study on Production of Useful Chemicals using Immobilized Plant Cells

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Papers (281)：

Yuken Hasebe, Masumi Yamada, Rie Utoh, Minoru Seki. Expansion of Chinese hamster ovary cells via a loose cluster-assisted suspension culture using cell-sized gelatin microcarriers. Journal of Bioscience and Bioengineering. 2023. 135. 5. 417-422
Mai Takagi, Masumi Yamada, Rie Utoh, Minoru Seki. A multiscale, vertical-flow perfusion system with integrated porous microchambers for upgrading multicellular spheroid culture. LAB ON A CHIP. 2023. 23. 9. 2257-2267
Akihiro Morita, Masumi Yamada, Rie Utoh, Kanta Momiyama, Hideki Iwadate, Minoru Seki. Formation of 3D tissues of primary hepatocytes using fibrillized collagen microparticles as intercellular binders. Journal of Bioscience and Bioengineering. 2022. 133. 3. 265-272
Natsumi Shimmyo, Makoto Furuhata, Masumi Yamada, Rie Utoh, Minoru Seki. Process simplification and structure design of parallelized microslit isolator for physical property-based capture of tumor cells. The Analyst. 2022. 147. 8. 1622-1630
Rie Utoh, Sakiko Enomoto, Masumi Yamada, Keigo Yamanaka, Yuya Yajima, Kazuya Furusawa, Minoru Seki. Polyanion-induced, microfluidic engineering of fragmented collagen microfibers for reconstituting extracellular environments of 3D hepatocyte culture. Materials Science and Engineering: C. 2021. 129. 112417-112417

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MISC (52)：

Separation and sorting of cells using magnetophoresis and laminar flows in microchannels. 2017. 214. 7-11
Preparation of Functional Microparticles using Droplets in a Non-Equilibrium State. 2017. 81. 6. 294-297
山田真澄, 関実. マイクロ流体デバイスによる微粒子の湿式分級 (特集新素材開発と最新製造技術). 化学装置. 2017. 59. 3. 33-38
Three-dimensional tissue engineering using collagen microparticles. 2017. 75. 5. 424-426
矢嶋祐也, 山田真澄, 堀綾香, 菅谷紗里, 鵜頭理恵, 関実. コラーゲン微粒子を導入した複合型3次元肝組織の作製と機能評価. 再生医療. 2016. 15

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Professional career (2)：

Work history (13)：

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Awards (6)：

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