Tonoki Ayako

トノキアヤコ | Tonoki Ayako

Affiliation and department：

Research field (3)： Pharmaceuticals - health and biochemistry , Neuroscience - general , Genetics

Research keywords (7)：ショウジョウバエ , インスリン , 遺伝学 , 代謝 , 認知症 , 記憶 , 老化

Research theme for competitive and other funds (10)：

2022 - 2025 Elucidation of the molecular and neural basis that controls the environmental factor-dependent forgetting mechanism
2021 - 2025 加齢と病的背景による神経異常機構の統合的解析
2018 - 2021 Molecular basis for the regulation of energy metabolism by the Notch-Mib1 pathway
2018 - 2020 Comprehensive screening for factors that regulate age-related memory decline
2017 - 2019 老化に伴う神経回路のスクラップ&ビルド

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Papers (21)：

Tohgo Kanoh, Takamasa Mizoguchi, Ayako Tonoki, Motoyuki Itoh. Modeling of age-related neurological disease: utility of zebrafish. Frontiers in Aging Neuroscience. 2024. 16
Sizhe Lyu, Noritaka Terao, Hirofumi Nakashima, Motoyuki Itoh, Ayako Tonoki. Neuropeptide diuretic hormone 31 mediates memory and sleep via distinct neural pathways in Drosophila. Neuroscience research. 2023. 192. 11-25
Xue Hou, Reina Hayashi, Motoyuki Itoh, Ayako Tonoki. Small-molecule screening in aged Drosophila identifies mGluR as a regulator of age-related sleep impairment. Sleep. 2023. 46. 5
Ayako Tonoki, Saki Nagai, Zhihua Yu, Tong Yue, Sizhe Lyu, Xue Hou, Kotomi Onuki, Kaho Yabana, Hiroki Takahashi, Motoyuki Itoh. Nitric oxide-soluble guanylyl cyclase pathway as a contributor to age-related memory impairment in Drosophila. Aging cell. 2022. e13691
Moeno Imai, Takamasa Mizoguchi, Meng Wang, Yingyi Li, Yoshinori Hasegawa, Ayako Tonoki, Motoyuki Itoh. The guppy (Poecilia reticulata) is a useful model for analyzing age-dependent changes in metabolism, motor function, and gene expression. Experimental Gerontology. 2022. 160. 111708-111708

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MISC (1)：

殿城亜矢子, 倉永英里奈, 富岡武泰, 濱崎純, 村田茂穂, 田中啓二, 三浦正幸. 神経変性疾患関連遺伝子探索と機能解析晩発性神経変性疾患における26Sプロテアソームの関与. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2008. 81回・31回. 3S25-6

Education (3)：

2006 - 2009 The University of Tokyo Graduate School of Pharmaceutical Sciences
2004 - 2006 The University of Tokyo Graduate School of Pharmaceutical Sciences
2000 - 2004 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy

Professional career (1)：

Work history (7)：

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