Rchr
J-GLOBAL ID：202001009458723714
Update date: Apr. 19, 2024
Narita Shin-ichiro
ナリタ シンイチロウ | Narita Shin-ichiro
Affiliation and department：
Job title：
教授
Research keywords (7)：
ABC transporter
, bacterial lipoproteins
, outer membrane protein
, protease
, bacterial cell surface
, envelope stress response
, 細胞内タンパク質分解
Research theme for competitive and other funds (13)：
- 2022 - 2025 Exploring the periplasmic chaperone network underlying outer membrane protein folding
- 2018 - 2021 Structural and Functional analysis on tripartite ABC transporters.
- 2018 - 2021 Molecular mechanisms underlying the selective membrane localization of bacterial lipoproteins
- 2018 - 2021 Analysis of the operating mechanism of BepA involved in the biosynthesis of bacterial outer membrane LPS translocon
- 2015 - 2018 Molecular mechanism for quality control of bacterial outer membrane by the periplasmic protease BepA
- 2012 - 2015 Analysis of a chaperone/protease involved in quality control of bacterial cell surface
- 2010 - 2011 Mechanism of substrate recognition by bacterial lipoprotein transport equipment
- 2007 - 2011 Biogenesis of Escherichia coli cell envlope.
- 2008 - 2009 Molecular mechanisms of lipoprotein-sorting in Pseudomonas aeruginosa
- 2005 - 2007 緑膿菌におけるリポタンパク質の局在化機構
- 2001 - 2005 Structure and function of the xenobiotic-antibiotic extrusion transporters
- 2003 - 2003 緑膿菌RND型多剤排出ポンプの新規活性評価法の開発
- 2000 - 2002 Structure and function of the xenobiotic-multidrug efflux pump
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Papers (40)：
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Kazuyuki Tao, Shin-ichiro Narita, Ui Okada, Satoshi Murakami, Hajime Tokuda. Dissection of an ABC transporter LolCDE function analyzed by photo-crosslinking. The Journal of Biochemistry. 2024. 175. 4. 427-437
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Yasushi Daimon, Shin-ichiro Narita, Ryoji Miyazaki, Yohei Hizukuri, Hiroyuki Mori, Yoshiki Tanaka, Tomoya Tsukazaki, Yoshinori Akiyama. Reversible autoinhibitory regulation of Escherichia coli metallopeptidase BepA for selective β-barrel protein degradation. Proceedings of the National Academy of Sciences. 2020. 117. 45. 27989-27996
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Mohammad Shahrizal, Yasushi Daimon, Yoshiki Tanaka, Yugo Hayashi, Shintaro Nakayama, Shigehiro Iwaki, Shin-ichiro Narita, Hironari Kamikubo, Yoshinori Akiyama, Tomoya Tsukazaki. Structural Basis for the Function of the β-Barrel Assembly-Enhancing Protease BepA. Journal of Molecular Biology. 2019. 431. 3. 625-635
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Shin-ichiro Narita, Hajime Tokuda. Bacterial lipoproteins; biogenesis, sorting and quality control. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2017. 1862. 11. 1414-1423
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Yasushi Daimon, Chigusa Iwama-Masui, Yoshiki Tanaka, Takuya Shiota, Takehiro Suzuki, Ryoji Miyazaki, Hiroto Sakurada, Trevor Lithgow, Naoshi Dohmae, Hiroyuki Mori, et al. The TPR domain of BepA is required for productive interaction with substrate proteins and the β-barrel assembly machinery complex. Molecular Microbiology. 2017. 106. 5. 760-776
ｍore...
MISC (5)：
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秋山芳展, 秋山光市郎, 岩間(舛井)千草, 大門康志, 檜作洋平, 水野慎也, 宮崎亮次, 森博幸, 禾晃和, 塩田拓也, et al. 大腸菌表層ストレス応答:インプットとアウトプットに働くプロテアーゼの機能. Institute for Fermentation, Osaka. Research Communications. 2019. 33
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大門康志, 舛井千草, 宮崎亮次, 櫻田洋人, 田中良樹, 鈴木健裕, 堂前直, 森博幸, 塚崎智也, 成田新一郎, et al. 大腸菌のペリプラズムプロテアーゼBepAは,TPR domainを介したタンパク質間相互作用により外膜機能を維持する. 日本農芸化学会大会講演要旨集(Web). 2017. 2017
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森博幸, 宮崎亮次, 町田裕紀子, 三登一八, 何あゆみ, 秋山光市郎, 大門康志, 舛井千草, 塚崎智也, 堂前直, et al. 部位特異的in vivo光架橋法を用いた生細胞内の動的タンパク質間相互作用解析. 日本蛋白質科学会年会プログラム・要旨集. 2016. 16th
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Narita, S, Tokuda, H. Sorting of bacterial lipoproteins to the outer membrane by the Lol system. In “Methods in Molecular Biology; Protein secretion”, A. Economou (ed), Humana press, in press. 2010
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Narita, S, Tokuda, H. The function of the ABC transporter LolCDE in protein transport to the outer membrane of E. coli. in The Enzymes. 2007. 25. 149-172
Education (2)：
- 1994 - 1999 Kyoto University Graduate School of Science
- 1990 - 1994 Kyoto University Faculty of Science
Work history (9)：
- 2020/04 - 現在 Yamagata Prefectural Yonezawa University of Nutrition Sciences Faculty of Nutritional Sciences professor
- 2016/04 - 2020/03 University of Morioka Faculty of Nutritional Sciences professor
- 2013/07 - 2016/03 University of Morioka Faculty of Nutritional Sciences Associate Professor
- 2013/04 - 2013/06 University of Morioka Faculty of Nutritional Sciences Assistant Professor
- 2010/07 - 2013/03 Kyoto University Institute for Virus Research Assistant Professor
- 2007/04 - 2010/06 The University of Tokyo Institute of Molecular and Cellular Biosciences Assistant Professor
- 2003/07 - 2007/03 The University of Tokyo Institute of Molecular and Cellular Biosciences Assistant Professor
- 2001/01 - 2003/06 Tokai University School of Medicine Assistant Professor
- 1999/04 - 2000/12 Japan Science and Technology Corporation Postdoctoral Fellow
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Awards (1)：
- 2010/03 - Japan Society for Bioscience, Biotechnology, and Agrochemistry JSBBA Award for Young Scientists ABC Transporters Involved in the Biogenesis of the Outer Membrane in Gram-Negative Bacteria
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