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J-GLOBAL ID：202001011346190440 Update date: Sep. 19, 2024

UEHARA YASUAKI

ウエハラヤスアキ | UEHARA YASUAKI

Affiliation and department：
Job title：助教

Research field (2)： Infectious disease , Respiratory medicine

Research keywords (1)： Osteoclast

Research theme for competitive and other funds (4)：

2021 - 2024 ErbB4の部位特異的糖鎖解析による糖鎖機能の解明
2021 - 2023 肺胞微石症における破骨細胞様多核巨細胞の機能解析と治療への応用
2013 - 2016 Studies of pulmonary surfactant proteins on new aspects of host defense functions: anti-tumor activity and defensive activity against disease development.
2012 - 2015 Studies on molecular basis of inhibitory effect of surfactant protein A against cytotoxicity of human b-defensin3.

Papers (27)：

Yoshihiro Hasegawa, Jennifer M Franks, Yusuke Tanaka, Yasuaki Uehara, David F Read, Claire Williams, Sanjay Srivatsan, Lori B Pitstick, Nikolaos M Nikolaidis, Ciara M Shaver, et al. Pulmonary osteoclast-like cells in silica induced pulmonary fibrosis. Science advances. 2024. 10. 28. eadl4913
Naoki Fujitani, Yasuaki Uehara, Shigeru Ariki, Ukichiro Hashimoto, Jo Mukai, Yoshihiro Hasegawa, Motoko Takahashi. Site-specific glycosylation analysis of epidermal growth factor receptor 2 (ErbB2): exploring structure and function toward therapeutic targeting. Glycobiology. 2024. 34. 3
Ukichiro Hashimoto, Naoki Fujitani, Yasuaki Uehara, Hiromi Okamoto, Atsushi Saitou, Fumie Ito, Shigeru Ariki, Akiko Shiratsuchi, Yoshihiro Hasegawa, Motoko Takahashi. N-glycan on N262 of FGFR3 regulates the intracellular localization and phosphorylation of the receptor. Biochimica et biophysica acta. General subjects. 2024. 1868. 4. 130565-130565
藤谷直樹, 上原康昭, 長谷川喜弘, 橋本宇吉郎, 有木茂, 高橋素子. ErbB2(HER2)の分子安定性に関与するN-glycansの機能の評価. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [1P-008]
橋本宇吉郎, 藤谷直樹, 上原康昭, 長谷川喜弘, 有木茂, 高橋素子. FGFR3のN型糖鎖は細胞膜への発現と活性を制御する. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [1P-009]

MISC (35)：

高橋素子, 藤谷直樹, 上原康昭, 長谷川喜弘. Site-specific Analysis of N-glycans of Receptor Tyrosine Kinases. Trends in Glycoscience and Glycotechnology (Web). 2023. 35. 206
高橋素子, 岡本弘美, 藤谷直樹, 上原康昭, 橋本宇吉郎, 長谷川喜弘. Structural and functional analysis of N-glycans of growth factor receptors. 日本糖質学会年会要旨集. 2023. 42nd
上原康昭, 長谷川喜弘, 高橋素子, McCormack Francis X. 呼吸器病学の若手研究最前線肺胞微石症における肺破骨細胞様細胞の機能解析. 日本呼吸器学会誌. 2022. 11. 増刊. 44-44
高橋素子, 齋藤淳, 長谷川喜弘, 藤谷直樹, 有木茂, 上原康昭, 松本邦夫. Structural and functional analysis of N-glycans of hepatocyte growth factor receptor MET. 日本糖質学会年会要旨集. 2022. 41st
齋藤淳, 長谷川喜弘, 藤谷直樹, 有木茂, 上原康昭, 松本邦夫, 高橋素子. METの糖鎖による機能制御メカニズムの解析. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [1T13m-014)]

Lectures and oral presentations (2)：

Work history (2)：

2020/04 - 現在 Sapporo Medical University Department of Biochemistry Assistant Professor
2015/06 - 2019/03 シンシナティ大学呼吸器内科ポスドク

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