SHICHI YUUKI

シチユウキ | SHICHI YUUKI

Affiliation and department：
Job title： Researcher

Research field (3)： Veterinary medicine , Tumor biology , Experimental pathology

Research keywords (5)：癌幹細胞 , electronic microscope , veterinary pathology , EMT , pancreatic cancer

Research theme for competitive and other funds (4)：

2024 - 2027 3次元培養を用いた膵臓がん細胞のプロテオーム解析:個別化治療と早期診断法の探索
2022 - 2025 Molecular biological analysis of gastrointestinal neuroendocrine tumors and development of new therapeutic drugs
2023 - 2024 膵癌の老化誘導薬の探索と老化細胞死誘導の研究
2021 - 2024 膵癌細胞の可変性制御による新規治療法の研究

Papers (12)：

Yuuki Shichi, Fujiya Gomi, Yasuko Hasegawa, Keisuke Nonaka, Seiichi Shinji, Kimimasa Takahashi, Toshiyuki Ishiwata. Artificial intelligence-based analysis of time-lapse images of sphere formation and process of plate adhesion and spread of pancreatic cancer cells. Frontiers in Cell and Developmental Biology. 2023. 11
Keisuke Nonaka, Kaiyo Takubo, Junko Aida, Yoriko Watai, Akiko Komatsu, Fujiya Gomi, Yuuki Shichi, Yuto Yamazaki, Toshiyuki Ishiwata, Hironobu Sasano, et al. Accelerated telomere shortening in adrenal zona reticularis in patients with prolonged critical illness. Frontiers in Endocrinology. 2023. 14
Keisuke Nonaka, Morito Kurata, Moriaki Tachibana, Akiko Komatsu, Yuuki Shichi, Fujiya Gomi, Toshiyuki Ishiwata, Kou Miyamoto, Tomio Arai. Chromosomal analysis of clonally related B-cell lymphomas with discordant immunoglobulin light-chain restrictions at different anatomical sites. Pathology international. 2022
Norihiko Sasaki, Kazumi Hirano, Yuuki Shichi, Yoko Itakura, Toshiyuki Ishiwata, Masashi Toyoda. PRC2-dependent regulation of ganglioside expression during dedifferentiation contributes to the proliferation and migration of vascular smooth muscle cells. Frontiers in cell and developmental biology. 2022. 10. 1003349-1003349
Yuuki Shichi, Fujiya Gomi, Yoshibumi Ueda, Keisuke Nonaka, Fumio Hasegawa, Yasuko Hasegawa, Nae Hinata, Hisashi Yoshimura, Masami Yamamoto, Kimimasa Takahashi, et al. Multiple cystic sphere formation from PK-8 cells in three-dimensional culture. Biochemistry and Biophysics Reports. 2022. 32. 101339-101339

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MISC (20)：

五味不二也, 佐々木紀彦, 志智優樹, 野中敬介, 豊田雅士, 石渡俊行. FGFR4阻害剤BLU554の膵癌細胞株に対する効果(Effects of the FGFR4 inhibitor BLU554(Fisogatinib) on pancreatic ductal adenocarcinoma cell lines). 日本癌学会総会記事. 2022. 81回. P-2077
佐々木紀彦, 平野和己, 志智優樹, 五味不二也, 吉村久志, 松下晃, 板倉陽子, 豊田雅士, 石渡俊行. Gp130/STAT3シグナル伝達は、長鎖ノンコーディングRNAのH19の発現を含む膵臓癌幹細胞の機能を調節する(Gp130/STAT3 signaling modulate pancreatic cancer stem cell feature including long non-coding RNA H19 expression). 日本癌学会総会記事. 2022. 81回. P-2100
石渡俊行, 志智優樹, 五味不二也, 野中敬介, 佐々木紀彦, 豊田雅士, 高橋公正, 新井冨生. 3次元培養による膵癌細胞株の上皮間葉系形質の増強(Enhanced epithelial and mesenchymal features of pancreatic ductal adenocarcinoma cell lines in 3-dimensional cultures). 日本癌学会総会記事. 2022. 81回. P-3173
志智優樹, 長谷川康子, 佐々木紀彦, 五味不二也, 野中敬介, 吉村久志, 高橋公正, 豊田雅士, 新井冨生, 石渡俊行. 3次元培養による膵癌培養細胞の上皮間葉系形質と粘液産生能の比較検討. 日本病理学会会誌. 2022. 111. 1. 239-239
佐々木紀彦, 平野和巳, 志智優樹, 板倉陽子, 石渡俊行, 豊田雅士. ヒト血管平滑筋細胞の形質転換とガングリオシド. 日本内分泌学会雑誌. 2022. 97. 5. 1517-1517

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Lectures and oral presentations (33)：

Investigation of mucin-producing capacity of pancreatic cancer cells in three-dimensional cullture
(The 113th Annual Meeting of the Japanese Society of Pathology 2024)
Time-lapse analysis of sphere formation and adhesive migration in pancreatic ductal adenocarcinoma cell lines
(The 82nd Annual Meeting of the Japanese Cancer Association 2023)
FGFR4 inhibitor BLU554 suppresses growth and invasion of pancreatic cancer cells and induces senescence
(The 82nd Annual Meeting of the Japanese Cancer Association 2023)
Morphofunctional analysis of human colon cancer cell lines in 3D culture
(The 82nd Annual Meeting of the Japanese Cancer Association 2023)
膵臓がん細胞のFGFR4阻害剤による増殖抑制と老化誘導
(TOBIRA第11回研究交流フォーラム 2023)

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Education (3)：

2013 - 2019 Nippon Veterinary and Life Science University Faculty of Veterinary Science School of Veterinary Medicine
2005 - 2007 University of Miyazaki Graduate School of Medicine (Master Course)
2001 - 2005 University of Miyazaki Faculty of Agriculture Department of Plant and Animal Sciences

Professional career (2)：

獣医学士 (日本獣医生命科学大学)
医学修士 (宮崎大学)

Work history (3)：

2020/04 - 現在 Tokyo Metropolitan Institute for Geriatrics and Gerontology Research Team for Geriatric Pathology, Division of Aging and Carcinogenesis
2019/04 - 2020/06 有限会社大相模動物ケアセンター
2007/04 - 2009/03 KAC Co., Ltd.

Awards (2)：

2022/03 - Springer Nature Scientific Reports Top 100 in Cancer 2021
2006/07 - The 43th Annual Meeting of the Society for Cryobiology “CRYO 06” (Hamburg, Germany) The Best Student Poster Award

Association Membership(s) (5)：

Medical Association of Nippon Medical School , Japanese Society of Pathology , Japanese Cancer association , Society of Atopy, Allegy, and Immunology in Veterinary Medicine , Japanese Society of Exotic Animal Medicine

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