2020 - 2023 Controls of inflammation and intestinal environment by intestinal bacterial metabolites for extending healthy life expectancy
2018 - 2021 Controls of intestinal lipid metabolism by fish oil
2015 - 2018 Analysis of mechanisms in postprandial lipidemia and identification of food-derived factors improving the postprandial lipidemia.
2015 - 2018 Mechanisms of inflammation control in functional phytochemicals: Counterplans against lifestyle-related diseases based on chronic inflammation
2010 - 2015 Development Mechanism and Physiological Roles of Brown Fat Regulating Energy Expenditure
2011 - 2013 Elucidation of the contribution of lymphatic transport to the intestinal absorption of various food factors
2010 - 2012 Analysis of intestinal lipid metabolism involved in the regulation for dietary lipid uptake.
2009 - 2010 Estimation of the absorption and metabolic mechanism of monoacylglycerols in the small intestine
2006 - 2010 Volume-sensor anion channel and mechano-sensor cation channel: Their functional modal shifts and molecular interaction
2005 - 2009 Visualization and analysis of membrane fusion mechanism during vesicular transport of transportosome by using multi-photon excitation process
2007 - 2008 Molecular analysis of activation mechanism of volume-sensitive chloride channel
2005 - 2008 Channel-mediated mechanisms of induction of and protection against cell death
Hisako Takahashi, Hiromu Morimoto, Miori Tanaka, Hirofumi Inoue, Tsuyoshi Goto, Teruo Kawada, Mariko Uehara, Nobuyuki Takahashi. Myricetin and myricitrin indirectly and directly increases uncoupling protein-1 mRNA expression in C3H10T1/2 beige adipocytes. Biochemical and biophysical research communications. 2024. 734. 150771-150771
Hisako Takahashi, Miori Morikawa, Emi Ozaki, Minami Numasaki, Hiromu Morimoto, Miori Tanaka, Hirofumi Inoue, Tsuyoshi Goto, Teruo Kawada, Fumio Eguchi, et al. A modified system using macrophage-conditioned medium revealed that the indirect effects of anti-inflammatory food-derived compounds improve inflammation-induced suppression of UCP-1 mRNA expression in 10T1/2 adipocytes. Bioscience, biotechnology, and biochemistry. 2024. 88. 6. 679-688
Hirofumi Inoue, Yusaku Shimizu, Hiroto Yoshikawa, Kohta Arakawa, Miori Tanaka, Hiromu Morimoto, Ayami Sato, Yuka Takino, Akihito Ishigami, Nobuyuki Takahashi, et al. Resveratrol Upregulates Senescence Marker Protein 30 by Activating AMPK/Sirt1-Foxo1 Signals and Attenuating H2O2-Induced Damage in FAO Rat Liver Cells. Journal of nutritional science and vitaminology. 2023. 69. 5. 388-393
Kohta Arakawa, Hirofumi Inoue, Akihito Ishigami, Ayami Sato, Yuka Takino, Miori Tanaka, Hiromu Morimoto, Nobuyuki Takahashi, Mariko Uehara. Release of SMP30 in Extracellular Vesicles under Conditions of Ascorbic Acid Deficiency Is Involved with Acute Phase Response in ODS Rat. Journal of nutritional science and vitaminology. 2023. 69. 6. 420-427
高橋尚子, 後藤剛, 河田照雄, 上原万里子, 高橋信之. A Novel System to Evaluate Anti-Inflammatory Effects of Food-Derived Compounds on Inflammation-Induced Inhibition of Heat Production in Beige Adipocytes. Foods & Food Ingredients Journal of Japan. 2023. 228. 4