Sakai-Takemura Fusako

Research theme for competitive and other funds (4)：

2024 - 2027 ヒト人工多能性幹細胞から遅筋・速筋の細胞を作り分ける誘導法の開発
2023 - 2026 老化による筋小胞体カルシウム枯渇に対する応答性変化と骨格筋機能への影響の解析
2019 - 2022 Molecular mechanisms by which Notch regulates proliferation and differentiation of human muscle progenitors
2016 - 2019 application of induced mesenchymal stem cells from human iPS cells to cell therapy in muscular dystrophy

Papers (6)：

Fusako Sakai-Takemura, Fumiaki Saito, Ken'ichiro Nogami, Yusuke Maruyama, Ahmed Elhussieny, Kiichiro Matsumura, Shin'ichi Takeda, Yoshitsugu Aoki, Yuko Miyagoe-Suzuki. Antioxidants restore store-operated Ca2+ entry in patient-iPSC-derived myotubes with tubular aggregate myopathy-associated Ile484ArgfsX21 STIM1 mutation via upregulation of binding immunoglobulin protein. FASEB bioAdvances. 2023. 5. 11. 453-469
Ahmed Elhussieny, Ken'ichiro Nogami, Fusako Sakai-Takemura, Yusuke Maruyama, Natsumi Takemura, Wael Talaat Soliman, Shin'ichi Takeda, Yuko Miyagoe-Suzuki. Mesenchymal stem cells derived from human induced pluripotent stem cells improve the engraftment of myogenic cells by secreting urokinase-type plasminogen activator receptor (uPAR). Stem cell research & therapy. 2021. 12. 1. 532-532
Ken'ichiro Nogami, Yusuke Maruyama, Fusako Sakai-Takemura, Norio Motohashi, Ahmed Elhussieny, Michihiro Imamura, Satoshi Miyashita, Megumu Ogawa, Satoru Noguchi, Yuki Tamura, et al. Pharmacological activation of SERCA ameliorates dystrophic phenotypes in dystrophin-deficient mdx mice. Human molecular genetics. 2021. 30. 11. 1006-1019
Ken'ichiro Nogami, Yusuke Maruyama, Ahmed Elhussieny, Fusako Sakai-Takemura, Jun Tanihata, Jun-Ichi Kira, Yuko Miyagoe-Suzuki, Shin'ichi Takeda. iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin. BMC musculoskeletal disorders. 2020. 21. 1. 479-479
Fusako Sakai-Takemura, Ken'ichiro Nogami, Ahmed Elhussieny, Kota Kawabata, Yusuke Maruyama, Naohiro Hashimoto, Shin'ichi Takeda, Yuko Miyagoe-Suzuki. Prostaglandin EP2 receptor downstream of Notch signaling inhibits differentiation of human skeletal muscle progenitors in differentiation conditions. Communications biology. 2020. 3. 1. 182-182

ｍore...

Lectures and oral presentations (6)：

ヒトiPS細胞を用いた難治性筋疾患に対する細胞移植治療法の開発.
(第39回国立精神・神経医療研究センター神経研究所研究所発表会)
患者血液からのiPS細胞の樹立と骨格筋分化細胞の実際 ~難治性筋疾患に対する創薬と再生医療への応用を目指して~
(世界脳週間2017レクチャー&ラボツアー「脳の科学の最前線」)
Robust derivation of transplantable skeletal muscle progenitor cells from human induced pluripotent stem (iPS) cells using a stirring bioreactor.
(International Society for Stem Cell Research Annual meeting (ISSCR2017))
ヒトiPS細胞を用いた難治性筋疾患に対する細胞移植治療法の開発.
(第38回国立精神・神経医療研究センター神経研究所研究所発表会)
RNA結合タンパク質Sfpqは骨格筋成長に必須である超長鎖遺伝子の発現を制御する.
(第39回日本分子生物学会年会)

ｍore...

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page