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J-GLOBAL ID:202001013998075506   Update date: Feb. 20, 2025

Kanno Yosuke

Kanno Yosuke
Affiliation and department:
Job title: Assistant Professor
Research field  (4): Other ,  Other ,  Other ,  Cell biology
Research keywords  (9): 皮膚 ,  骨 ,  血管 ,  macrophage ,  Inflammation ,  Bone ,  Fibrinolysis ,  vascular dysfunction ,  Fibrosis
Research theme for competitive and other funds  (6):
  • 2017 - Alpha2-antiplasmin をターゲットとした強皮症治療法の開発
  • 2013 - 2016 The roles of uPA/uPAR on the inflammatory osteoclastogenesis
  • 2014 - α2APをターゲットとした強皮症治療法の開発
  • 2014 - Alpha2-antiplasmin をターゲットとした強皮症治療法の開発
  • 2011 - 2012 The role of uPAR in the inflammation-induced bone resorption
Show all
Papers (63):
  • Yosuke Kanno, Kinomi Toyama, Haruna Shibata, Osamu Matsuo, Kei-Ichi Ozaki. α2-antiplasmin is associated with macrophage activation and fibrin in a macrophage activation syndrome mouse model. Clinical and experimental immunology. 2024
  • Yosuke Kanno. The uPA/uPAR System Orchestrates the Inflammatory Response, Vascular Homeostasis, and Immune System in Fibrosis Progression. International journal of molecular sciences. 2023. 24. 2
  • Y Kanno, E Shu. α2-Antiplasmin as a Potential Therapeutic Target for Systemic Sclerosis. Life. 2022. 12. 3. 396
  • Yosuke Kanno, Momoko Hirota, Osamu Matsuo, Kei-Ichi Ozaki. α2-antiplasmin positively regulates endothelial-to-mesenchymal transition and fibrosis progression in diabetic nephropathy. Molecular biology reports. 2022. 49. 1. 205-215
  • Yosuke Kanno, Kaho Tsuchida, Chihiro Maruyama, Kyoko Hori, Hanako Teramura, Shiho Asahi, Osamu Matsuo, Kei-Ichi Ozaki. Alpha2-antiplasmin deficiency affects depression and anxiety-like behavior and apoptosis induced by stress in mice. Journal of basic and clinical physiology and pharmacology. 2021
more...
MISC (37):
  • Yosuke Kanno. The roles of α2AP in the pathogenesis of systemic sclerosis. Atlas of science. 2016
  • 河下映里, 辻大輔, 菅野陽介, 石原慶一, 秋葉聡, 伊藤孝司. Sandhoff病モデルマウス由来ミクログリアにおけるMIP-1α産生のUDP刺激による亢進. 日本薬学会年会要旨集(CD-ROM). 2016. 136th
  • Yosuke Kanno, Akira Ishisaki, Eri Kawashita, Naoyuki Chosa, Keiichi Nakajima, Tatsuji Nishihara, Kuniaki Toyoshima, Kiyotaka Okada, Shigeru Ueshima, Kenji Matsushita, et al. Plasminogen/plasmin modulates bone metabolism by regulating the osteoblast and osteoclast function (vol 286, pg 8952, 2011). JOURNAL OF BIOLOGICAL CHEMISTRY. 2014. 289. 22. 15154-15154
  • Y. Kanno, E. Kawashita, A. Kokado, K. Okada, S. Ueshima, H. Kaji, O. Matsuo, H. Matsuno. Alpha2-antiplasmin regulates the development of fibrosis by Pgf2 alpha synthesis through Atgl/Ipla2. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2013. 11. 34-34
  • Y. Kanno, A. Kokado, E. Kawashita, M. Tani, K. Okada, S. Ueshima, O. Matsuo, H. Matsuno. The role of a2AP in the development of renal interstitial fibrosis. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2013. 11. 438-438
more...
Books (4):
  • Effect of Alpha2-Antiplasmin on Tissue Remodeling.
    Nova Science Pub Inc 2012
  • Proteins Researcher Biographical Sketches and Research Summaries (Protein Science and Engineering: Protein Biochemistry, Synthesis, Structure and Cell (1ST)
    Nova Science Pub Inc; 1 edition 2012
  • Effect of Alpha2-Antiplasmin on Tissue Remodeling.
    Nova Science Pub Inc 2012
  • SERPINS AND PROTEIN KINASE INHIBITORS: NOVEL FUNCTIONS, STRUCTURAL FEATURES AND MOLECULAR MECHANISMS
    Nova Science Publishcrs, Inc. 2010
Lectures and oral presentations  (83):
  • 血管障害発症におけるuPARの役割
    (第95回日本生化学会大会 2022)
  • 糖尿病性腎症における内皮間葉転換及び線維化進行に対するα2-antiplasminの役割
    (日本薬学会第142年会 2022)
  • The effect of matrix metalloproteinases-3 on the deposition of α2AP in systemic sclerosis
    (Society for Investigative Dermatology (SID) 2019 Meeting Abstract Supplement 2019)
  • The roles of α2-antiplasmin in the pathogenesis of fibrotic diseases
    (第39回 日本血栓止血学会学術集会 学術推進委員会(SPC)シンポジウム 2017)
  • The antifibrotic effect of alpha2AP neutralization in systemic sclerosis dermal fibroblasts and mouse models of systemic sclerosis
    (40th Annual Meeting of the Japanese Society for Investigative Dermatology (JSID) 2015)
more...
Professional career (1):
  • 博士(理学) (筑波大学大学院)
Work history (3):
  • 2015/04 - 現在 Doshisha Women's College of Liberal Arts Assistant Professor
  • 2017/06 - 2023/03 岐阜大学大学院 医学系研究科 非常勤講師
  • 2008/04 - 2015/03 Doshisha Women's College of Liberal Arts Assistant Professor
Committee career (2):
  • 2017/06 - 現在 岐阜大学大学院医学系研究科 非常勤講師
  • 2015 - 現在 Scientific Reports (Nature Publishing Group) Editorial Board
Awards (5):
  • 2017/04 - 2017 Albert Nelson Marquis Lifetime Achievement Award
  • 2012/06 - 国際血栓止血学会 第58回国際血栓止血学会 ISTH Young Investigator Awards
  • 2009/05 - 日本糖尿病学会 第52回日本糖尿病学会年次学術集会プレジデントポスター受賞
  • 2008/11 - 日本血栓止血学会 第31回日本血栓止血学会学術集会 優秀賞
  • 2005/03 - 筑波大学大学院 筑波大学大学院 生命環境科学研究科長賞
Association Membership(s) (5):
日本血栓止血学会 ,  日本研究皮膚科学会 ,  日本リウマチ学会 ,  日本皮膚科学会 ,  日本生化学会
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