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J-GLOBAL ID：202001014098544051 Update date: Apr. 01, 2025

Shibata Shun

シバタシュン | Shibata Shun

Affiliation and department：
Job title：助教

Research field (1)： Developmental biology

Research theme for competitive and other funds (9)：

2024 - 2028 Implantation organoid model using human multilevel stem cells and elucidation of immune tolerance mechanism
2024 - 2027 三次元多階層細胞モデルを駆使した着床免疫パラダイムの深層解明
2024 - 2026 ヒト胚着床オルガノイドモデルを活用した母子間競合的細胞コミュニケーションの解析
2023 - 2026 ヒト胎盤の発生・分化を調節する分子メカニズムと疾患の病態解明
2021 - 2025 ヒト胎盤形成のエピゲノム制御と母体-胎盤間分子シグナルコミュニケーションの理解

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Papers (21)：

Shun Shibata, Takahiro Arima. Recapitulating human embryo implantation using stem cells and organoids. Translational and Regulatory Sciences. 2024. 6. 3. 68-71
Hiroaki Okae, Shun Shibata, Takahiro Arima. Common and uncommon findings in marmoset and human trophoblast stem cells. Cell Stem Cell. 2024. 31. 10. 1387-1388
Shun Shibata, Shun Endo, Luis A. E. Nagai, Eri H. Kobayashi, Akira Oike, Norio Kobayashi, Akane Kitamura, Takeshi Hori, Yuji Nashimoto, Ryuichiro Nakato, et al. Modeling embryo-endometrial interface recapitulating human embryo implantation. Science Advances. 2024. 10. 8
Takeshi Hori, Hiroaki Okae, Shun Shibata, Norio Kobayashi, Eri H Kobayashi, Akira Oike, Asato Sekiya, Takahiro Arima, Hirokazu Kaji. Trophoblast stem cell-based organoid models of the human placental barrier. Nature Communications. 2024. 15. 1. 962-962
Takanori Shimizu, Akira Oike, Eri H Kobayashi, Asato Sekiya, Norio Kobayashi, Shun Shibata, Hirotaka Hamada, Masatoshi Saito, Nobuo Yaegashi, Mikita Suyama, et al. CRISPR screening in human trophoblast stem cells reveals both shared and distinct aspects of human and mouse placental development. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 51. e2311372120

MISC (30)：

柴田峻, 有馬隆博. 【胎盤形成と母児連関発達を運命づけるメカニズム】ヒト胚着床の試験管内再構築と分子機序. 実験医学. 2025. 43. 4. 486-491
柴田峻, 濱田裕貴, 有馬隆博. 【遺伝診療・ゲノム医療の最新動向-産婦人科医のためのナビゲーション-】総論ゲノムインプリンティングとヒト疾患. 産科と婦人科. 2025. 92. 2. 152-158
柴田峻, 有馬隆博. ヒト生殖メカニズム解明のための研究フロントラインヒト胚着床モデルの作製. 日本生殖医学会雑誌. 2024. 69. 4. 304-304
柴田峻, 有馬隆博. ヒト子宮内膜オルガノイドモデルを用いたヒト着床現象の模倣. 日本生殖内分泌学会雑誌. 2024. 29. 23-26
柴田峻, 小林枝里, 有馬隆博. 新たな子宮内膜オルガノイドの確立とヒト胚着床現象のin vitroでの再現. オルガノイド研究 ~培養・作製、活用、臨床応用~. 2024

Patents (7)：

Lectures and oral presentations (10)：

Recapitulating human embryo implantation using stem cells and organoids
(Virtual Gastrulation Zoom Talks 2025)
Modeling the interphase between embryo and endometirum to understand embryo implantation in humans
(Foundation for Reproductive Medicine Conference 2024 2024)
ヒト胚着床モデルの作製
(第69回日本生殖医学会学術講演会・総会シンポジウム 2024)
幹細胞・オルガノイドを用いたヒト胚着床現象の試験管内での再現
(第20回 Top Runners in TRS 2024)
Modeling Embryo-Endometrial Interface Recapitulating Human Embryo Implantation
(ISSCR 2024 2024)

Education (2)：

Professional career (1)：

Work history (3)：

2020/04 - 現在 Tohoku University Graduate School of Medicine Assistant Professor
2014/06 - 2020/03 Osaka University Graduate School of Medicine Research Scientist
2012/04 - 2014/05 ROHTO Pharmaceutical Co., Ltd. R&D division Scientist

Awards (4)：

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